Ama-benzodiazepines, ama-opiates, nama-barbiturates angakwazi ukuphefumula konke
Uma usebenzisa imithi ethile kadokotela-njenge-benzodiazepines, ama-opiate noma ama-opioid, nama-barbiturates-ungase uzibuze ukuthi lezi zingathinta kanjani ingozi yokuphefumula ukuphefumula . Njengoba le mithi ingaba nomthelela kuzo zonke izakhiwo zokulala , ithoni yomzimba, nokuphefumula, imiphumela ingabalulekile.
Benzodiazepines
Iklasi lemithi ebizwa ngokuthi i- benzodiazepines ihlanganisa imithi eminingi ehlose ukuqeda ukukhathazeka.
Abanye babo basebenza njengama-relaxant muscle noma asetshenziswa njengama-anticonvulsants ukuphatha izifo. Njengoba le mithi ingabangela nokulala, ngezinye izikhathi isetshenziselwa ukudlula isikhathi esifushane ukusiza ubuthongo (nakuba ukusetshenziswa okungavamile kule njongo kudikibala). Eminye imithi ye-benzodiazepine ihlanganisa:
- I-Alprazolam (i-Xanax)
- I-chlordiazepoxide
- I-Clonazepam (I-Ionopin)
- I-Clorazepate
- I-Diazepam (i-Valium)
- I-Lorazepam (i-Ativan)
- Quazepam
- I-Midazolam
- I-Estazolam
- Flurazepam
- I-Temazepam (Ukubuyisela)
- I-Triazolam
I-benzodiazepines yenza eduze kwe-GABA receptor ebusweni bamangqamuzana, okwenza ukuba i-chloride ihambe ngokukhululekile kuzo zonke iziteshi zabo. Ukuze ukwelashwa kokulala , ziye zanqotshwa imithi evikelekile engabinaki ingozi yokuphefumula ukuphefumula noma ukuphefumula ukuphefumula.
Ama-opiates
Ama-opiates (ngezinye izikhathi abizwa ngokuthi i-opioids noma ama-narcotics) ayingxenye yemithi ejwayele ukusetshenziselwa ukuphumula ubuhlungu. Amanye asetshenziselwa ukuphatha isifo sohudo noma ukukhwehlela.
Njengoba zingabangela ubuthongo njengomthelela ohlangothini, bangaba nemiphumela ebalulekile ekuphefumuleni ngesikhathi sokulala kwakho. Amanye ama-opiate ajwayelekile ahlanganisa:
- I-Hydrocodone
- I-oxycodone
- Fentanyl
- Mepridine
- I-Methadone
- Morphine
- I-Sufentanil
- I-Codeine
- I-propoxyphene
- Buprenorphine
- I-Pentazocine
Lawa ma-opiates abophezela kumamukeli we-opioid ahlukahlukene ngaphakathi kwesistimu yezinzwa nakwezinye izindawo emzimbeni.
I-opioids ibangela ukwanda kokuphefumula, ukuphefumula okungavamile, nokuphefumula okungajulile. Kungabangela i- apnea yokulala ephakathi .
I-Barbiturates
I-barbiturates yilasilasi lemithi eyake isetshenziselwa ukudluliswa, kodwa ngenxa yemiphumela emibi kakhulu, kuhlanganise nengozi yokuxhomeka nokuxoshwa, baye baqedwa njengama-sleep aid. Bangabangela i-coma ezinkambisweni ezinobuthi. Ezinye ze-barbiturates zifaka:
- Amobarbital
- Phenobarbital
- I-Pentobarbital
- I-Secobarbital
- Thiopental
I-barbiturates yenza isithuthi se-sodium ne-potassium emasethini, okungavimbela uhlelo olusebenzayo olusebenzayo ku-brainstem. Lokhu kungabangela ukuguqulwa ngisho ne-coma futhi kunemiphumela ebalulekile ngokuphefumula. Le mithi akumele isetshenziswe njengezinsiza zokulala zokuphatha ukuleleka.
Indlela Le Mithi Eyenza Ngayo Ukuphuza Ekulele
Ngamunye walawa mithi angakunqanda ukuphefumula kwakho futhi wenze ukuthi umoya wakho ongaphezulu uphumeke kakhulu. Lokhu kungase kubize ukuphefumula okuphazamisekile kokulala, okufana nokuphefumula kokuphefumula. Njengoba le mithi iphinde icindezele izinga lakho lokuqaphela, ungase ukwazi ukuvikela indlela yakho yokuhamba emoyeni ngokwanele. Lokhu kungaholela ekuphazanyeni ukuphefumula, ukuphelelwa amandla noma ukuphefumula, ngisho nokufa. Lezi mithi zivame ukubandakanyeka ekufeni kwabantu abangaphezu kokudlula, okubandakanya phakathi kwabantu abadumile.
Okokugcina, le mithi ingaba nomthelela ohlukile emakhakheni akho okulala, okuholela ekuphazamiseni ubuthongo ngisho nalapho uhlala ungazi lutho.
Uma une-apnea yokulala, kufanele ube ne-polysomnogram (i-PSG) eyenziwa uma usebenzisa noma iyiphi yale mithi ukuqapha imiphumela emibi. Kubalulekile ukuxoxa ngalezi zingozi ngudokotela wakho ukuze anqume ukuthi izinzuzo zomuthi zingaphezu kwamandla okulimaza esimweni sakho.
Imithombo:
I-Dolly, i-F kanye ne-Block, A. "Imiphumela ye-flurazepam kokuphefumula okuphazamisekile kokulala nokuphazamiseka kokuhlwa ebusuku ngezihloko ezingenakuqhathaniswa." Am J Med 1982; 73: 239.
I-Harvey, i-RA ne-Champe, i-PC. "Pharmacology." ULippencott , uhlelo lwesibili, 2000.
I-Katzung, i-BG. "I-Basic & Clinical Pharmacology." Lange , edition 9, 2004.