Labo abanenkinga yobuchopho kusuka e-chemo noma ekukhunjweni kwememori kusuka ekuguga , i-Alzheimer's noma i- dementia yanoma yiluphi uhlobo ngokuvamile bafuna izimpendulo.
Njengoba ucwaningo mayelana ne-jellyfish amaprotheni luyisandulela, kubonakala sengathi kunesidingo sokungavumi kakhulu, ukugwema ukwehlisa ithemba ngaphandle kwesizathu, kodwa kunamathuba amaningi okungabaza kwesayensi enempilo.
Kungenzeka yini ukuthi amaprotheni angeke asebenze?
Impendulo lapha ibukeka ibe yebo ekhanyayo, ilandelwa yi-HOWEVER enkulu.
Yebo, ososayensi bayazi ukuthi amaprotheni okudla angakwazi ukwenza imisebenzi ye-biologic-amaprotheni okudla asebenze nje njengemithombo yamamino acid kodwa futhi njengabadlali abasebenza ngandlela-thile: Ngaphakathi kwepheshana le-GI, amaprotheni nemikhiqizo yabo yokudiliza, ama-peptide, angaxhumana nama-receptors akhipha ama-hormone, asithinta izinto ezifana nokukhulelwa kwesisu nokumuncwa, ukudlulisela izimpande ze-neural ebuchosheni nokuguqula amabhaktheriya ahlala emanzini, i-microflora.
Ngakho-ke, ingabe amaprotheni we-jellyfish ayenomthelela omuhle endaweni ethile kude nomgudu wamathumbu? Yebo, kungenzeka. Kodwa hhayi ngendlela ongacabanga ngayo. Amaprotheni okudliwa awaziwa ukuthi ahamba kusukela emathanjeni emathunjini kuya ku-neurons ebuchosheni.
Kubamakholwa, kungase kududuza ukwazi ukuthi ukwesekwa kwenziwa e-United States, enezimiso eziningi zokuthenga umthengi kunamaphilisi okwenziwe, okushoyo, e-China. Kodwa uma ukhuluma ngezinzuzo, zihlale zikhona izinkinga nezinselelo ezihlobene nokuhamba ngokweqile okusemandleni ukuze kuqinisekiswe emitholampilo.
I-Jellyfish Brain Protein?
Iprotheni ye-jellyfish ebuzwayo i-apoaequorin, i-protein e-calcium ebopha kuqala etholakala i-jellyfish Aequorea Victoria ngo-1962. I-jellyfish namaprotheni ayo anezo zonke izinto ezenziwa i-Hollywood e-effects-studio studio: i-jellyfish ingaveza ukukhanya okuluhlaza okwesibhakabhaka ukukhululwa okusheshayo kwe-calcium (i-Ca 2+), okusebenzisana ne-photoprotein aequorin.
I-calcium, empeleni, yingxenye yokusekelwa kwesayense kwiwebsite yomkhiqizo, mhlawumbe njengesizathu sokukholelwa. Kodwa kunenkinga. Kungenzeka ukuthi i-Apoaequorin yayiyogaya esiswini kanye ne-GI ipheshana ukuze ingabe isakwazi ukusebenza njengoba iyenzayo ku-jellyfish, abaphikisayo abambe.
Ingabe i-Apoaequorin isekela umsebenzi wobungqabavu obunempilo?
Ngokusho kwewebhusayithi yomkhiqizo, apoaequorin isekela umsebenzi wezobuchopho obunempilo. * Kukhona i-asterisk ngemuva kokumangalelwa, okubhekisela kumsebenzi wokuzihlangula: * Lezi zitatimende azizange zihlolwe yi-Food and Drug Administration. Lo mkhiqizo awuhloselwe ukuxilonga, ukwelapha, ukwelapha noma ukuvimbela noma yisiphi isifo.
Ngakolunye uhlangothi, isithasiselo iprotheni kanye namaprotheni ukudla, okuyinto lapho igayiwe futhi ifakwe, ijwayele ukusekela impilo yeseli kanye nomsebenzi, kuhlanganise ne-neurons. Ngakho isimangalo somkhiqizo cishe siyiqiniso. Iwebhusayithi yomkhiqizo iphinde ibhekisele ekutholeni okutholayo, kuhlanganise nokuhlola okulawulwa kwe-placebo okuyi-doublebo blind (I-Madison Memory Study) ukusekela izimangalo zokucutshungulwa okuthuthukisiwe. Abanye abagxeki baye baphikisana nokubaluleka kwalezi zifundo, kodwa lokho akusho ukunganaki ukutholakala kwabo. Lokhu kuyisezela, ngakho ubufakazi obudingekayo ngaphambi kokumaketha akufani nalokho okwenziwe ngomuthi omusha.
Lokho kusho ukuthi kunombiko ovela ku-NBC izindaba zikaMaggie Fox ezibonisa ukuthi iMfundo yeMadison ihlulekile ukukhombisa ukuthuthukiswa okuphawulekayo eqenjini lezokwelapha phezu kweqembu le-placebo kunoma yimiphi imisebenzi engama-9 engqondweni.
Amaphuzu ambalwa atholakala kuwebhusayithi mayelana nokuthi umkhiqizo usebenza kanjani ubonakala ubeseka ngokuzihlukanisa, kodwa awunamatheli ndawonye ngokuchaza incazelo yesayensi. Isibonelo, cabanga ngesitatimende esithi "Apoaequorin yiprotheni izidingo zethu zempilo kodwa ziyancipha ekugugeni." Nakuba lokhu kungase kube yiqiniso, akukho isimangalo esenziwe ukuthi izithako zokudla eziqukethe i-apoaequorin zilungisa le nkinga.
Uthola umqondo.
Ngaphansi
Akukho bufakazi obucacile bokuthi abusebenzi , kodwa okufanayo kungashiwo ngezinto eziningi, njengokugeza okubumba noma ukusebenzisa i-enema ikhofi.
> Imithombo:
UJahan-Mihan A, uLuvyvy BL, u-El Khoury D, no-Anderson GH. Amaprotheni Okudliwa Njengokunqunywa Kwemisebenzi Yametaboliki Ne-Physiologic Ye-Tract Gestrointest Tract. Amakhemikhali. May 2011; 3 (5): 574-603.
Ukuhlola, Ukuthobela, Ukuphoqelela, Nokuphenywa Kwamacala Obugebengu. I-Quincy Bioscience Manufacturing Inc 10/16/12.
I-Moran DL, Tetteh AO, Goodman RE, Underwood MY. Ukuvikelwa kokuphepha kweprotheyini yokukhiphela i-calcium, i-Apoaequorin, echazwe ngu-Escherichia Coli. I-toxicology yokulawulwa kanye ne-pharmacy. 2014; 69 (2): 243-249.
> Maggie Fox, i-NBC News. I-Jellyfish Memory Supplement I-Prevagen I-Hoax, i-FTC ithi.