Lezi zinkinga ezimbili ezizimele zivame ukuhlangana ndawonye
Uma unesifo se-celiac , nawe unengozi ephakeme yesifo se-autoimmune. Eqinisweni, amaphesenti angama-10 abantu abanesifo se-celiac empeleni banesimiso se-autoimmune, isilinganiso esiphezulu kunabantu abaningi, izifundo zibonisa. Phakathi naleso sikhathi, phakathi kwamaphesenti angu-1.5 namaphesenti angu-6.7 abantu abanesifo sengqondo se-autoimmune futhi banesifo se-celiac.
Kungenzeka ukuthi lezi zimo ezimbili ziba nemvelaphi ejwayelekile yezakhi zofuzo kanye nezinqubo ezingaphansi. I-Celiac ivame ukuvela nezinye izifo ezizimele, ikakhulukazi uhlobo lwesifo sikashukela, i-rheumatoid arthritis, kanye nesifo se-autoimmune . Ucwaningo lwango-2016 lubonise ukuthi isifo se-celiac sandisa ingozi yesifo segciwane kubantu abane-type 1 yesifo sikashukela, isibonelo.
Isayensi asikaze ichaze imbangela yezifo ezizimele , kodwa abanye abacwaningi bathi inqubo yokulimaza ingase ingenele inqubo yesifo kubantu abaphila ngokwezakhi zofuzo.
Nakuba kungakabonakali, okungenani ucwaningo olulodwa lwezokwelapha lubonisa ukuthi isifo se-thyroid esiyingozi singase sibe gluten, okungenani kwabanye abantu. Iziguli zesifo se-Celiac ezithatha ukudla okungenayo i-gluten zinganciphisa amathuba abo okuthuthukisa ukukhubazeka kwesifo se-thyroid, ngokusho kwalolu cwaningo, okubonisa ukuthi ukudla kwe-gluten kubantu abanobucayi kungase kubangele isifo se-thyroid.
Izinhlobo Zokukhubazeka Kwe-Thyroid Autoimmune
Kubantu abanesifo sokuzimela, amangqamuzana egazi amhlophe omzimba ahlasela ngokungalungile izitho noma ezinye izinhlobo zamathambo. Esifweni se-celiac ngokukhethekile, amangqamuzana egazi amhlophe ahlasele emgodini omathumbu omncane. Futhi, nge-auto-immune disorder yegazi, amangqamuzana egazi elimhlophe ahlasela isifo se-thyroid-okuyinto encane efana ne-butterfly enemibala emqaleni wakho olawula umzimba wakho.
Ukuzilimaza ngokuzenzakalelayo kwesifo se-thyroid kungabangela ukuba igciwane lakho le-thyroid lingabi nakakhulu, okuthiwa yi-Graves, noma lingasebenzi, okuthiwa yi-Hashimoto's disease.
Izifo zamathuna
E-Graves isifo, amaphampu wegciwane aphuma amaningi amahomoni thyroxine, eyaziwa njenge-T4, ne-triiodothyronine, noma i-T3. Abesifazane abaneminyaka engaphezu kwengu-20 banengozi enkulu kakhulu yalesi simo, kodwa amadoda nawo aseyingozi.
Izimpawu ze -roid ezingaphezu kokusebenza zihlanganisa ukungalali , ukucasula, ukulahlekelwa isisindo, ukuzwela ukushisa, nokubuthakathaka kwemisipha. Iziguli zesifo se-Graves nazo zingase zihlakulele amehlo anonya futhi i-goiter ephawulekayo.
Isifo sikaHashimoto
Ngesikhathi esifanayo, esesifo sikaHashimoto, i-thyroid ikhiqiza kakhulu i-T3 ne-T4. Izimpawu ezincane ze-thyroid zifaka ukukhathala, ukuzuza isisindo, ubuthakathaka, ukuzwela emakhazeni, imisipha ekhukhulayo, amalunga anamandla, ukuqothulwa nokuvuvukala ubuso. Nalapha, abesifazane banengozi enkulu yalesi sifo kunamadoda.
Ukuxhumeka kwe-Gluten ku-Autoimmune Diseases
Esikhathini sokucwaninga okuphakamisa ukuthi ukwelashwa kwesifo se-celiac ngokudla okungenalutho kwe-gluten kunganciphisa ingozi yokuhlaziya isifo se-thyroid esizimele, iqembu labacwaningi base-Italy liqhathanisa nesifo sesifo se-celiac kubantu abanobuciko, ezigulini ze-thyroid ezizimele, nakwiqembu "iziguli ezigulayo" ezinezifo ezingezona ezenzakalelayo ze-thyroid, umdlavuza, nesifo senhliziyo.
Abacwaningi babhala ukuthi ukusabalala kwesifo se-celiac eqenjini lesifo segciwane "kwakukhulu kakhulu kunazo zonke izinhlangano zokulawula ezempilo nezigulayo." Bathi, "Kungenzeka ukuthi ubudlelwane phakathi kwezifo ze-celiac nokuzimela ezigulini ezingenalutho ezingelashwa kubangelwa ukudla kwe-gluten."
Olunye ucwaningo luye lwabonisa ukuthi amasosha omzimba aqondene nomzimba-lawo okubonisa ukuthi amangqamuzana egazi amhlophe omzimba ahlaselwa izitho ezithile, njengegciwane le-thyroid-liyanyamalala ngemva kwezinyanga ezintathu kuya kweziyisithupha ekudleni okungenayo i-gluten.
Kungenzeka ukuthi abacwaningi babhala ukuthi "isifo se-celiac esingatholakali singabangela ezinye izifo ngokushintsha ezinye izindlela ezingaziwa ezingaziwa." Uma kuyiqiniso, ukuhambisana ngokuqinile nokudla okungenalutho kwe-gluten kunganciphisa ingozi yeziguli zesifo se-celiac ezenza izifo ezizenzekelayo ezizimele, kuhlanganise nesifo se-autoimmune.
Ucwaningo lwanyatheliswa ku- Digestive Diseases and Sciences ngoFebruwari 2000.
Isikrini Sezokwelapha Zama-Universal Celiac Akukhuthazwa
Ithimba lokucwaninga lase-Italy laphakamisa ukuthi zonke iziguli zesifo se-autoimmune zingase zizuze ekuhlolweni kwesifo se-celiac. Kodwa-ke, kukhona ukungavumelani emphakathini wezokwelapha mayelana nokuthi ngabe ukuhlolwa okunjalo kuyadingeka yini.
I-American Gastroenterological Association Institute, esitatimendeni sika-2006 mayelana nokuxilongwa nokuphathwa kwezifo ze-celiac, yaphawula ukuthi iziguli ezine-autoimmune isifo se -roid zisengozini enkulu ye-celiac, kodwa zanezela ukuthi "akukho mqondo ophoqelela ukuhlolwa kwesiguli kweziguli ezinezifo ze-thyroid ngenxa yesifo se-celiac lapho kungekho khona izimpawu ezibonisa noma ezihambisana nesifo se-celiac. "
Esikhundleni salokho, lesi sikhungo siphakamise ukuthi abahlengikazi bahlolele iziguli zesifo se-thyroid eziphethe izibonakaliso ezibonisa isifo se-celiac . Odokotela abaningi balandela le mihlahlandlela.
Imithombo:
I-American Gastroenterological Association (AGA) Institute. "Isitatimende se-AGA Institute for Medical Position Statement on the Diagnosis and Management of Celiac Disease." I-Gastroenterology 2006; 131: 1977-1980
Ch eng CY et al. Izifo ze-Celiac kanye nezifo ze-Thyroid Autoimmune. Imithi Yezokwelapha kanye nocwaningo 2007 Okthoba; 5 (3): 184-192.
Elfström P et al. "Ingozi yezifo ze-Thyroid kubantu ngabanye abanezifo ze-Celiac." Journal of Endocrinology Clinic & Metabolism. i-doi: 10.1210 / jc.2008-0798
Izifo zamathuna. Ishidi Lolwazi Lomthengi. Insizakalo Yokwazisa Ngezifo Zomzimba We-Endocrine kanye ne-Metabolic Diseases.
Izifo zikaHashimoto. Ishidi Lolwazi Lomthengi. Insizakalo Yokwazisa Ngezifo Zomzimba We-Endocrine kanye ne-Metabolic Diseases.
Kurien M et al. Izifo Zama-Celiac Ukwandisa Ingozi Yezifo Ze-Thyroid Ezigulini Ezinesifo Sikashukela Sesi-1: Isifundo Seqembu Likazwelonke. Ukunakekelwa yisifo sikashukela . 2016 Mar; 39 (3): 371-5.