Izimpawu Ezivamile Wonke Owesifazane Kufanele Azi
I-Polycystic ovarian syndrome (i-PCOS) iyisifo se-endocrine kanye nesizathu esivamile sokungabikho kwabesifazane. Ku-PCOS, ukungahleleki kwe-hormonal kungathinta ngqo uhlelo lokuzala, okuholele ekuvuthweni okungavamile noma okungekho. Nakuba imbangela ye-PCOS ingaziwa, ingathinta amaphesenti ayisishiyagalombili wabesifazane.
I-PCOS ibonakala ngokubunjwa kwama-cysts amancane, agcwele amanzi ovunguvungu.
Ngesikhathi sokuhlolwa kwe-ultrasound, i-cysts benign iyofana ne-string ye amapharele.
I-PCOS yinkinga eyinkimbinkimbi engabonakalisa ngenqwaba yezibonakaliso ezikhungathekisayo futhi ezivame ukwenzeka. Ukuvuvukala, ukumelana ne-insulini, nokwanda kwama-hormone wesilisa ( androgens ) konke kunomthelela kwizici zesifo.
Izimpawu ezinhlanu ezivame kakhulu ze-PCOS yizi:
Ukungenzi lutho
I-PCOS yiyona imbangela eyinhloko yokwelashwa okungenayo i-ovulatory . Ngenxa yalokho, abesifazane abane-PCOS bazobhekana nobunzima obuningi lapho bezama ukukhulelwa. Kuvamile ukuthi abesifazane abane-PCOS babe nezinkathi ezingekho noma ezingavamile. Ezinyangeni ezithile, i-ovulation kungenzeka ingenzeki nakanjani.
Ukukhula ngokweqile Kwesobuso Nokunyuka Kwezinwele
I-Hirsutism yigama lezokwelapha elisetshenziselwa ukuchaza ukukhula kwezinwele ngokweqile. Kubangelwa ukukhiqizwa ngokweqile kwe-androgen (ikakhulukazi i-testosterone, i-hormone ehlobene nezici zesintu). Abesifazane abane-PCOS bangase babone ukukhula kwezinwele ngokweqile esifubeni, ubuso, emuva, isisu esincane, iminwe, nezinzwane.
Ukulahlekelwa izinwele
Abesifazane abane-PCOS bangase baphinde balahlekelwe izinwele , futhi ngenxa yokukhiqizwa ngokweqile kwe-androgen. Kungase kuthuthuke ngokwakho noma kuhambisane ne-hirsutism. Ukulahlekelwa izinwele kuvame ukufana nalokho okubonwe ekugqeni kwendoda yesilisa nge-thinning eceleni kwezinwele kanye / noma umqhele wekhanda. Ezimweni ezimbi kakhulu, abesifazane abano-PCOS bangathola i- alopecia , ukuthuthukiswa kwekhasi elilodwa noma ngaphezulu le-circular bald engakwazi ukuhlanganisa eyodwa kokulandelayo.
Ukuphikiswa kwe-Insulin nohlobo lwesifo sikashukela
Ukuphikiswa kwe-insulin kuvamile ku-PCOS, okuphazamisa abaningi abangamaphesenti angu-70 abesifazane abanesifo. Ukuphikiswa kwe-insulin kubangela ukwanda kwamazinga kashukela egazini. Nakuba lesi simo singase sibe nezimpawu ezimbalwa ezibonakalayo, kubhekwe njengengozi enkulu engozini yokuthuthukiswa kwesifo sikashukela sohlobo lwe-2 .
Uhlobo lwe-2 lwesifo sikashukela lungabonakala ngenqwaba yezibonakaliso ezikhungathekisayo nakwezinye izikhathi ezinzima. Lokhu kufaka ukukhathala, umbono obonakalayo, ukutheleleka okuvamile, izilonda zokuphulukisa kancane, ukuvuthwa okuvamile, nokwanda kwendlala nokoma. Isifo sesikhathi eside singabangela izinkinga ezithinta inhliziyo, izinso, amehlo, izinzwa, nokuzwa.
Izinkinga Zesikhumba
Akuyona into engajwayelekile ukuthi ukungalingani kwe-hormone kuhlale kuthinta isikhumba. Nge-PCOS, abesifazane bazovame ukuzwa ama-acne noma ukuthuthukisa amathegi esikhumba. Ezimweni ezimbi kakhulu, bangase babe nesimo esibizwa ngokuthi i- hidradenitis suppurativa (HS) ekhonjiswe ngamabhomu noma amathumba angaqondakaliyo futhi ngezinye izikhathi aphefumulayo endaweni yesifuba, isifuba noma i-groin.
Esinye isimo esaziwa njenge- acanthosis nigricans ingabonakalisa ngezikhwama zesikhumba esimnyama, esikhuni entanyeni, emathangeni, noma emanzini. Lokhu ngokuvamile kuyisibonakaliso sokuphikiswa kwe-insulin.
I-apnea yokulala
I-apnea yokulala , ebonakala ngokugwinya nokuphefumula okungavamile ebusuku, ibonakala nakwabesifazane abane-PCOS.
I-apnea yokulala ibonakala ixhunyaniswa nenhlanganisela yesisindo esandayo namazinga aphezulu we-testosterone (okugcina okuthinta ngokuqondile ukulala kwe-receptors ebuchosheni). I-apnea yokulala nayo iyaziwa ngokufaka umfutho wegazi ophezulu futhi ingabangela ushintsho lwezinto eziguquguqukayo ezihambisana nokuphikiswa kwe-insulin.
> Umthombo:
> McCartney, C. noMarshall, J. "Polycystic Ovary Syndrome." I-New England Journal of Medicine. 2016; 375: 54-64.