Ukuphikiswa kwe-insulin yikhono elinciphile lamanye amangqamuzana omzimba ukuphendula kwi-insulin. Kungukuqala komzimba okungahambisani kahle noshukela (futhi khumbula ukuthi wonke ama-carbohydrate awela phansi ushukela emizimbeni yethu). Omunye wemisebenzi esemqoka ye- insulin ukuthola amanye amangqamuzana omzimba ukuba 'avulwe' ukuze athathe i-glucose (noma, ngokunembile ukugcina i- glucose njengamafutha).
Ukuphikiswa kwe-insulin kwenzeka lapho amangqamuzana engavumeli ukuvula umnyango lapho i-insulin ifika ingqongqoza. Uma lokhu kwenzeka, umzimba ubeka insulin engaphezulu ukuze iqinise iglucose yegazi (ngakho-ke amangqamuzana angasebenzisa i-glucose). Ngokuhamba kwesikhathi, lokhu kuholela esimweni esibizwa ngokuthi "hyperinsulinemia" noma "insulin eningi egazini." I-Hyperinsulinemia ibangela ezinye izinkinga, kubandakanya ukwenza kube nzima ngomzimba ukusebenzisa amafutha agcinwe amandla.
Yini Ebangelwa Ukuphikiswa Kwe-Insulin?
Asazi lonke indaba, kodwa ngokuqinisekile, izakhi zofuzo zidlala ingxenye enkulu. Abanye abantu empeleni bazalwa ngokumelene ne-insulin. Ukuntuleka komsebenzi okwenza ukuthi amangqamuzana angabe esabela kancane kwi-insulin. Iningi labachwepheshe liyavuma ukuthi ukukhuluphala kuholela ekuncintiseni okukhulu kwe-insulin. Kodwa-ke, cishe ngokuqinisekile futhi isebenza ngenye indlela: Ukuphikiswa kwe-insulin kukhuthaza ukuzuza isisindo. Ngakho-ke umjikelezo onamandla ungasungulwa nge-insulin ukumelana nokunyusa isisindo, okukhuthaza ukuphikiswa kwe-insulin.
Yiziphi Izinkinga Ezenza Ukuphikiswa Kwe-Insulin?
Ngaphandle kokuthola isisindo esiningi, ukumelana ne-insulin kuhlobene nokukhuluphala kwesisu, umfutho wegazi ophezulu , i-triglycerides ephakeme, ne- HDL ephansi ("i-cholesterol enhle"). Lezi zimo ziyingxenye yenkinga yezinkinga ezibizwa ngokuthi i-metabolic syndrome (ebizwa ngokuthi i-insulin resistance syndrome).
Ngenxa yokuthi leli qembu lezimpawu livela ndawonye, kunzima ukwazi ukuthi yini ebangela lokho, kodwa isifo se-metabolic isisindo esiyingozi engozini yesifo sofuba nesifo sikashukela sohlobo lwe-2.
Yeka Ukuphi Ukuphikiswa Kwe-Insulin Okuvamile?
Ukuphikiswa kwe-insulin kuyaba okuvamile. Kubuye kwandiswe ngeminyaka yobudala, okungahle kuhlobene nokuthambekela kokuthola isisindo phakathi ne-midlife. Ucwaningo olulodwa lubonise ukuthi amaphesenti angu-10 asebekhulile abhekana nemigomo yesifo se-metabolic egcwele, kuyilapho lesi sibalo senyukela kuma-44 amaphesenti eqenjini lobudala elingaphezu kuka-60. Ngokusobala, ukusabalala kwe-insulin ukumelana yedwa (ngaphandle kwe-syndrome egcwele) kuphakeme kakhulu.
Ngingayitshela Kanjani Uma Nginamandla Okumelana Ne-Insulin?
Uma ukhuluphele ngokweqile, cishe usuke unamandla okuvimbela i-insulin, ikakhulukazi uma unesisindo esiningi esiswini sakho. Uma unesinye sezibonakaliso ze-syndrome ye-metabolic echazwe ngenhla, kungenzeka ukuthi ube nokungaxilisi i-insulin. Ukwengeza, abantu abaphendula kahle ekudleni kwe-carbohydrates bangase babe namathuba amaningi okuba bangakwazi ukumelana ne-insulin. Ngisekelwe kulesi sihloko esithi, "Ingabe I-Carb Ephansi Kuwe?", Ngokuyinhloko kunesiqiniseko sokuthi abantu abaphikisana ne-insulin bangase bazuze kakhulu ekunciphiseni ama-carbohydrates ezidlweni zabo.
Abanye ochwepheshe basebenzisa ukuhlolwa kwe-insulin yokuzila ukudla ukusiza ukunquma i-hyperinsulinemia ne-insulin ukumelana.
Uma Ukuphikiswa Kwe-Insulin Isinyathelo Sokuqala, Yini Eya Elandelayo?
Uma i-pancreas igcina ibeka amazinga aphezulu e-insulini, ekugcineni ayikwazi ukuqhubeka yenza. Incazelo ejwayelekile yukuthi i-beta-amangqamuzana ase-pancreas "aphelile," kodwa empeleni kungenzeka ukuthi i-insulini ephezulu kanye / noma ngisho negazi eliphakeme kakhulu liqala ukulimaza amaseli e-beta . Kunoma yikuphi, ngaleso sikhathi, i-glucose yegazi iqala ukunyuka nakakhulu, futhi indlela eya ku- Type 2 yesifo sikashukela iqala ngempela.
Uma ukudla i-glucose yegazi kufinyelela ku-100 mg / dl, kubizwa ngokuthi "ama-prediabetes," futhi uma ufinyelela ku-126, kubizwa ngokuthi "isifo sikashukela." Ungazibona ukuthi lezi zingxube ezingabonakali ngendlela eqhubekayo yokuntuleka komzimba ukubhekana noshukela: Okokuqala, i-insulin ayisebenzisi kangako, futhi-ke akukho-insulin eyanele yokuthola umsebenzi.
Ngokushesha esingangenelela kule nqubo, ngcono kuzoba khona.
Imithombo:
> Grundy, Scott, et al "Definition of Metabolic Syndrom e." Ukujikeleza 109 (2004): 433-438.
> Weir, Gordon noBonner-Weir, uSusan. "Izinyathelo Ezinhlanu Zokuguqula I-Beta-Dysfunction Cell Ngesikhathi Uqhubeka Nokuthi Sikashukela." Isifo sikashukela 53 (2004): S16-S21.