Funda kabanzi mayelana ne-Keratin Skin Cells
I-Keratinocytes yilona uhlobo olujwayelekile kakhulu lwamaseli esikhumba. Benza i-keratin, iphrotheni enikeza amandla isikhumba, izinwele, nezipikili. I-Keratinocytes ifomu engxenyeni ejulile, ephansi ye-basal yesikhumba futhi kancane kancane ihambela phezulu, iba ngamaseli angama-squamous ngaphambi kokufinyelela phezulu kwesikhumba ngaphezu kwenyanga. Ngenxa yalesi sizathu, ngezinye izikhathi amagciwane e-non-melanoma esikhumba njenge- basal cell carcinoma kanye ne- squamous cell carcinoma ngezinye izikhathi abizwa ngokuthi i-keratinocyte cancers.
Uhlobo oluvame kakhulu lomdlavuza we-keratinocyte yi-basal cell carcinoma.
Iyini i-Basal Cell Carcinoma?
I-basal cell carcinoma uhlobo lomdlavuza wesikhumba. I-basal cell carcinoma iqala kumaseli ase-basal - uhlobo lweseli ngaphakathi kwesikhumba okhiqiza amangqamuzana omzimba wesikhumba njengoba abantu abadala befa.
I-basal cell carcinoma ivame ukubonakala njenge-waxy bump, nakuba ingathatha ezinye izinhlobo. I-Basal cell carcinoma ivele kaningi ezindaweni ezikhungweni ezivame ukuvezwa elangeni, njengobuso bakho nentamo.
Iningi le-basal cell carcinomas kucatshangwa ukuthi libangelwa ukutshala isikhathi eside emisebeni ye-ultraviolet (UV) kusuka elangeni. Ukugwema ilanga nokusebenzisa i-sunscreen kungasiza ukuvikela ngokumelene ne-basal cell carcinoma.
Izimpawu ze-Basal Cell Carcinoma
Ama-basal cell carcinomas ngokuvamile ahlakulela ezingxenyeni ezikhanyisiwe zelanga zomzimba wakho, ikakhulukazi ikhanda nentamo yakho. Inombolo encane kakhulu eyenzeka esihlalweni nasemilenzeni. Kodwa i-basal cell carcinomas ingenzeka nakwezinye izingxenye zomzimba wakho ezingavamile ukuba zivezwe ekukhanyeni kwelanga.
Nakuba isibonakaliso esijwayelekile sesifo somdlavuza wesikhumba siyisifo esibuhlungu esingeke siphulukise noma ukuthi siphume futhi sihlabe ngokuphindaphindiwe, umdlavuza we-basal we-basal ungase ubonakale njengo:
- I-white white noma i-waxy bump, evame ukuba nemithambo yegazi ebonakalayo, ebusweni bakho, ezindlebeni noma entanyeni. I-bump ingase igeze futhi ithuthukise i-crust. Kubantu abanobumnyama abanobumnyama, lolu hlobo lomdlavuza lungaba nsundu noma lube mnyama.
- I-patch, i-scaly, e-brown noma inyama enemibala emhlane noma esifubeni sakho. Ngokuhamba kwesikhathi, lezi zikhonkwane zingakhula kakhulu.
- Ngokungajwayelekile, umbala omhlophe, we-waxy. Lolu hlobo lwe-basal cell carcinoma kulula ukuwabheka, kodwa lungase lube uphawu lwe-cancer ebizwa ngokuthi i-morpheaform basal cell carcinoma.
Izimbangela ze-Basal Cell Carcinoma
I-Basal cell carcinoma iyenzeka uma elinye lamaseli ase-skin basal edala ukuguquguquka kwi-DNA yayo. Amaseli ase-basal atholakala phansi kwe-epidermis - ungqimba lwangaphandle lwesikhumba. Amaseli ase Basal akhiqiza amangqamuzana omzimba wesikhumba Njengoba amangqamuzana omzimba wesikhumba akhiqizwa, atshayela amangqamuzana asebekhulile angene esikhumbeni, lapho amangqamuzana amdala efa khona.
Inqubo yokudala amangqamuzana omzimba wesikhumba ilawulwa yi-DNA ye-basal cell. Ukuguquguquka kwe-DNA kwenza ukuba isisal basal yande ngokushesha futhi iqhubeke ikhula lapho ingase ife. Ekugcineni, amangqamuzana angajwayelekile angakha isisu esinomdlavuza.
Ukukhanya kwe-ultraviolet nezinye izimbangela
Umonakalo omkhulu ku-DNA kumaseli ase-basal kucatshangwa ukuthi uvela emisebeni ye-ultraviolet (UV) etholakala elangeni nasemakhanini okuthunga okuhweba kanye nemibhede yokuqothula. Kodwa ukuchayeka kwelanga akuchazi ukwelashwa kwesikhumba okuthuthuka esikhumbeni esingajwayelekile ekukhanyeni kwelanga.
Lokhu kubonisa ukuthi ezinye izici zingase zibe nomthelela engozini yomdlavuza wesikhumba, njengokungathi ubhekene nezinto ezinobuthi noma unesimo esinciphisa isimiso sakho somzimba.
Nini Ukubona Udokotela
Yenza i-aphoyintimenti nodokotela wakho uma unezibonakaliso noma izimpawu ezikukhathazayo.
Inkomba:
I-Mayo Clinic. I-Basal Cell Carcinoma. http://www.mayoclinic.org/diseases-conditions/basal-cell-carcinoma/basics/definition/con-20028996