Iseli le-squamous luhlobo lwe-cell epithelial. Lawa maseli atholakala ezindaweni eziningi zomzimba. Abantu bavame ukucabanga ngamaseli e-epithelial njengamaseli "esikhumba". Nokho, lokho kudukisa. Amaseli e-Epithelial angatholakala athole izakhi eziningi zomzimba womuntu - hhayi nje ngaphandle.
Amangqamuzana ama-squamous amangqamuzana e-epithelial flat. Ngokuphambene, amangqamuzana e-cuboid epithelial asemaceleni futhi amangqamuzana e-columnar epithelial angama-rectangular.
Amaseli agqamile atholakala ezinhlokweni ezihlukahlukene zomzimba. Ungathola amangqamuzana omzimba omlomo emlonyeni, ezindebeni nasekilinikini. Ziyabonakala nasezingxenyeni eziphakathi kwesikhumba. Amangqamuzana ama-squamous amangqamuzana ama-epithelial amahle kakhulu. Bakha amaphepha amashadi amangqamuzana. Njengalokhu, ziyasiza njengezinto zokufaka izicubu cishe yonke indawo.
Iningi labantu lijwayele ukujwayela i-squamous cell lapho kuthiwa bane- squamous cell carcinoma . Lolu uhlobo lomdlavuza oluthinta izingqimba ze-epithelium. I-squamous cell carcinomas yiyona mdlavuza ovame kakhulu emlonyeni womlomo . Lezi zomshukela zivame ukutholakala esibelethweni nasesikhumba.
Amaseli Ayisigqila Nomdlavuza Wesibeletho
Kukhona esinye isizathu ukuthi abesifazane bangase bajwayele i-term squamous cell. Kungenzeka ukuthi kungakapheli umdlavuza, imiphumela engavamile yePap smear ngezinye izikhathi ibhekwa njengezilonda ezincane ze-intraepithelial.
Lokhu ukuxilongwa ngokuqondile kwePap smear engavamile. Uma uthola lokhu kuhlolisiswa, kusho ukuthi amangqamuzana ase-squamous atholakale emtholampilo athathe i-morphology engavamile, noma isimo. Noma kunjalo, lawa maseli ayenayo ngempela umdlavuza. Eqinisweni, izilonda ezingaphansi kwe-squamous intraepithelial (LSIL) zivame ukuziphulukisa ngaphandle kokungenelela.Lezi zilonda nazo ngezinye izikhathi zibizwa ngokuthi i- dysplasias yesibeletho ,
Iningi lamangqamuzana omlomo wesibeletho kanye ne-pre-cancers kubangelwa ukutheleleka nge- HPV . I-papillomavirus yabantu igciwane futhi iguqula amangqamuzana angama-squamous of the cervix. Kungabuye futhi iguqule futhi iguqule amaseli ezinye izicubu emzimbeni. Kuye ngezimo, ngokuhamba kwesikhathi, amangqamuzana aphilile angathatha lawa maseli aguqulwe noma angaqhubeka ekhula ngokungavamile futhi abe nomdlavuza. Lokho kusho ukuthi ukutheleleka kwe-HPV eminingi yomlomo wesibeletho akuholeli emdlalweni wesibeletho somlomo wesibeletho. Umzimba uvame ukukwazi ukuqeda lezi zifo kuphela.
Amanye ama-Cancers e-Squamous Cell & HPV
Ukutheleleka kwe-HPV kuhlotshaniswa ne-squamous khancer cells kwezinye izindawo. Lokhu kufaka phakathi umdlavuza wekhanda nentamo, i-vulva, i-penis, ne-anus. Eqinisweni, ososayensi abathile balinganisela ukuthi ezine ezinezifo zomdlavuza zibangelwa i-HPV! Ngenhlanhla, i-Cancers ehlobene ne-HPV itholakale iphathwa kangcono kunezinye ukwelashwa kwamangqamuzana ezincane - okungenani ekhanda nasentanyeni.
Abantu bathola kanjani ukwelapha okuhlobene ne-HPV? Kuzo zonke izindawo ezishiwo ngenhla, ukuhanjiswa kwe-HPV kucatshangwa ukuthi kuyisondo. Ubulili be-oral kanye nesandulela ngculazi kungadlulisela i-HPV, ngaphezu kokulala ngokobulili.
Izwi kusuka
Kuyaqondakala ukuthi imiphumela engavamile yePap smear ingase ibonakale icasula.
Noma kunjalo, khumbula ukuthi izinguquko eziningi zomlomo wesibeletho zihamba zodwa. Lokhu akulona iqiniso nje nge-ASCUS smears - amangqamuzana angama-atypical okubaluleka okungaqiniseki. Izilonda eziningi ezingaphambi komdlavuza nazo zihamba zodwa zingakapheli unyaka noma ezimbili.
Ngakho-ke, uma une-Pap smear engavamile, melana nesifiso sokwesaba! Kunalokho, khuluma nodokotela wakho mayelana nezinyathelo ofuna ukuzenza phambili. Udokotela wakho angase anikeze ukwelashwa. Noma kunjalo, bangase balinde futhi babone indlela. Ucwaningo olunzulu luye lwabonisa ukuthi abesifazane abanoPap olandelelayo bayaphonsa izinyanga eziyisithupha emva kokupheka okungejwayelekile kwezinga eliphansi benza kanye nalabo abathola ikholpocopy ne-biopsy.
Lezi zinhlobo eziningi zokuhlasela nokuphathwa.
Ingozi yokutheleleka kwe-HPV inganciphisa nokugoma. I-Cervarix ne-Gardasil imithi emibili ekhonjisiwe ukunciphisa ingozi yokutheleleka kwe-HPV. Kodwa-ke, ziphumelela kakhulu uma zinikezwa ngaphambi kokuba abantu abasha bahlanganyele ngokocansi. Uma ungumuntu osemusha noma umzali womuntu omdala osetsheni, khuluma nodokotela wakho ukuthi ngabe umgomo we-HPV uyindlela enhle kuwe. Umuthi wokugoma we-HPV unconywa njengendlela yokugoma yokujwayelekile yamadoda nabesifazane abasha abaphakathi kweminyaka yobudala engu-11 no-12. Unganqunywa kuze kube iminyaka engu-27, kuye ngezimo.
Umthombo:
UDexeus S, uRubio R, Bassols G, Jakob D, Ojeda J, i-Labastida R. Papilloma igciwane lesandulela ngculaza. Umdlavuza we-precancer kanye nomdlavuza we-epidermoid. I-Eur J Gynaecol Oncol. 1992; 13 (2): 167-76.
R. Abu-Eid noG. Landini "I-Tissue Architecture kanye ne-Cell Morphology ye-Squamous Cell Carcinomas Ngokuqhathaniswa ne-Granular Cell Tumors 'Pseudo-epitheliomatous Hyperplasia ne-Normal Oral Mucosae." e- Losa GA et al. (ed) (2005) Ama-Fractals ku-Biology and Medicine
> KA, Kim MJ, Lee KH, Lee IH, Kim MK, Hwang CS, Jeong MS, Kee MK, Kang C, Cho CH, Kim SM, Hong SR, Kim KT, Lee WC, Park JS, Kim TJ. Impact ye-HPV Genotypes Ephakeme-Ingozi Okunye kune-HPV 16/18 kwiNkundla Yemvelo Ye-Cytology Engavamile Yomlomo wesibeletho; Isifundo seKorea seKhosi ye-HPV. I-Cancer Res Treat. 2016 Mar. 9 ini: 10.4143 / crt.2016.013.
Stephenson RD, uDenehy TR. Ukulungiswa okusheshayo okusheshayo kwe-acute-onset vulvar intraepithelial neoplasia 3 kwabesifazane abasha: uchungechunge lwamacala. I-J Low Genit Tract Dis. 2012 Jan; 16 (1): 56-8. i-doi: 10.1097 / LGT.0b013e31822d93ee.
> Sundström K, Lu D, Elfström KM, Wang J, Andrae B, Dillner J, Sparén P. Ukulandelelwa Kwabesifazane abanezinkinga ezingavamile ze-Cervical Cytological Ukubonisa i-Ascus noma i-LSIL: Isifundo se-National Cohort. Am J Obstet Gynecol. 2016 Juni 22. pii: S0002-9378 (16) 30477-X. doi: 10.1016 / j.ajog.2016.07.042.