Kube khona okuningi okukhuluma nge-hormone dehydroepiandrosterone, noma i-DHEA, nokuthi ithinta kanjani ubulili bethu, kanye nempilo yethu yengqondo nengokwenyama. Ingabe i-DHEA inikeza ukusizwa okuphumelelayo kwezinkinga zobulili, izinkinga zempilo yengqondo, noma izinkinga zempilo? Noma ingabe ukuthenga i-DHEA kuyinkunkuma yemali yakho?
Kuyini i-DHEA?
I-DHEA iyi-hormone ye-steroid kanye nesandulela se-androgens (testosterone) kwabesifazane.
Ama-gland adrenal akhiqiza iningi le- DHEA elikhona kwabesifazane kuyilapho ama-ovaries enza inani elincane le hormone enamandla enamandla.
Izinga le-DHEA ngokwehla ngokwemvelo njengoba sikhula. Ngesikhathi uneminyaka engu-80 ubudala, inani le-DHEA elikhiqizwa ngumzimba wakho lilinganiselwa ku-5 kuya kwezingu-10 kuphela emalini yenani elikhiqizwa ezingeni eliphezulu kakhulu ngesikhathi sobusha nokukhula kwabantu abadala.
Izimangalo eziningi ziye zafakwa ku-DHEA. Kungenzeka ukuthi wezwe ukuthi inga:
- ukwandisa izinga lakho lamandla
- ukukusiza ukuba ulahlekelwe isisindo
- ukunciphisa inqubo yokuguga
- khuthaza isimiso sakho somzimba omzimba
- ukunciphisa ingozi yomdlavuza nesifo senhliziyo
- phuthukisa imemori yakho
Kodwa-ke, ososayensi abasaqondi ukuthi i-DHEA isebenza kanjani, yintoni injongo yayo emzimbeni, nokuthi ngabe i-DHEA iphephile futhi isebenza kahle yini.
Okutholakele kwakamuva
Ngokwesifundo esincane saseJalimane esashicilelwe eNew England Journal of Medicine (NEJM), abacwaningi bathole ukuthi i-DHEA ithuthukise ubulili nenhlalakahle kubesifazane abangu-24 abatholwa ukuthi abanakho ukungakwazi ukusebenza kahle.
Ucwaningo oluphindwe kabili lwathola ukuthi abesifazane abathatha ama-50 mg we-DHEA nsuku zonke babika ukwanda okuphawulekayo ukuthi babecabanga kangaki ngocansi, ukuthi banesithakazelo kangakanani ekusebenzeni ngokocansi, kanye namazinga abo kokubili ukwaneliseka ngokobulili ngokomzimba nangokomzimba.
Laba besifazane nabo babike ukuthuthukiswa kwezinkinga zempilo yengqondo njengemikhuba yokucindezela, ukucindezeleka, ukukhathazeka, nezinye izimo ezingokwengqondo.
Ukuthuthukiswa okuphawulekayo kwabonakala ezinyangeni ezine ngemuva kokuqala ukwelashwa.
Imiphumela emibi yabika ngamaphesenti angama-20 abahlanganyeli bezocwaningo futhi ihlanganisa isikhumba esinamafutha, induna, nokunyuka kwezinwele zomzimba. Ngaphezu kwalokho, owesifazane oyedwa wabika ukulahlekelwa izinwele . Ukunciphisa inani le-DHEA lona wesifazane uthathe ukuqeda izinwele.
Olunye ucwaningo oluthile lweziguli ezingu-22 zesilisa nabesifazane abatholwa ukucindezeleka okukhulu, ezanyatheliswa kuyi- American Journal of Psychiatry , zathola ukwehla kwamaphesenti angu-50 ekucindezelekeni cishe cishe kwesigamu sabathintekayo abathatha iDHEA. Ababhali bokutadisha bathi ukuhlolwa okukhulu kunesidingo ukuhlola ukuphepha kokuthatha i-DHEA nokuthi i-hormone kufanele ithathwe kuphela ngaphansi kokuqondiswa kwezokwelapha.
Ngabe Kufanele Ngisongeze Nge-DHEA?
Abanye bakholelwa ukuthi i-DHEA iyasiza ekwelashweni kwe-hormone esikhundleni sokumisa isikhashana futhi isikisela ukuthatha isilinganiso esincane salesi sengezo. Kodwa-ke, ukungqubuzana okukhulu kuhlala ngokuphathelene nokuxhaswa nale hormone enamandla, futhi ucwaningo olucophelela luyalulekwa ngaphambi kokuba uqale ukuthatha lesi sengezo .
Inkinga enkulu ngokuhlolwa kwe-DHEA yukuthi iningi lifake inani elincane labahlanganyeli (njengoba kuphawuliwe ezifundweni ezingenhla).
Ukusesha "i-DHEA" kunoma imiphi imiphumela ye-injini yokusesha emakhasini amaningi e-DHEA abathengisi bangezelayo.
Kubalulekile ukuphawula ngaphambi kokuthenga noma yikuphi yale mikhiqizo ku-intanethi noma esitolo sakho sendawo ukuthi i-DHEA yokungezelela ayigunyaziwe yi-FDA nganoma yikuphi ukusetshenziswa , futhi ngenxa yokuthi i-DHEA ihlukaniswa njengesengezo sokudla , abakhiqizi be-DHEA abanaso isibopho sokufakazela ukuthi imikhiqizo yabo iphephile noma isebenza kahle.
Ngaphambi kokuzama noma yiziphi izithako ze-OTC, kuhlale kuwumqondo omuhle ukuxoxa ngawo nochwepheshe wezempilo kuqala.
Imithombo:
I-Wiebke Arlt, MD, uFrank Callies, MD, uJohn Christoph van Vlijmen, Ines Koehler, uMartin Reincke, MD, uMartin Bidlingmaier, MD, uDoris Huebler, MD, Michael Oettel, Ph.D., Michael Ernst, MS, Heinrich Maria Schulte, MD, noBruno Allolio, MD; "I-Dehydroepiandrosterone Indawo Yabafazi Abangenakwanela"; NEJM, Umqulu 341: 1013-1020, September 30, 1999, Inombolo 14; http://content.nejm.org/cgi/content/full/341/14/1013.
Owen M. Wolkowitz, MD, Victor I. Reus, MD, Audrey Keebler, BA, Nicola Nelson, BA, Mirit Friedland, BA, uLouann Brizendine, MD no-Eugene Roberts, Ph.D .; Ukwelapha Okubili Kokuphulukisa Ukucindezeleka Okukhulu Nge Dehydroepiandrosterone "; Am J Psychiatry 156: 646-649, Ephreli 1999; http://ajp.psychiatryonline.org/cgi/content/full/156/4/646.