Benadryl kanye 'PM' Izinsiza Zokulala Kungabangela Ukudideka, Ukugcinwa Kwe-Urinary
Izinkinga eziwela noma ezihlala zilele ezenzeka ngokuqwashisa zingabangela abantu abaningi ukuthola isixazululo ema-aisles ekhemisi. Ukusetshenziswa kwezinsiza zokulala ezingaphezu kwele-counter, ikakhulukazi lezo eziqukethe i- diphenhydramine (njenge-Benadryl), evamile. Kodwa-ke, kunezizathu ezithile zokuthi kungani abantu asebekhulile nabakudala bengasebenzisi imithi equkethe i-diphenhydramine ukusiza ukulala.
Funda ukuthi kungani abantu asebekhulile kufanele beqe ukusetshenziswa kwamaphilisi okulala anesici ngenxa yobungozi bemiphumela emibi njengokudideka, ukuwohloka komqondo, ukugcinwa komchamo, kanye nokuzondeka.
Iyini i-Diphenhydramine ku-Benadryl naku- "PM" Ukulala amaphilisi?
I-Diphenhydramine yisithako esivame kakhulu kunazo zonke ezitholakala kumaphilisi okulala ngaphezulu kwe-counter. Kuyinto isithako esiyinhloko eBenadryl, futhi kubangela ukulala njengethonya elibi. Ngakho-ke kuvame ukufakwa emalungiselelweni e "PM" asetshenziselwa ukwelapha ukuleleka, kufaka phakathi: iTylenol PM, Advil PM, noZzzQuil .
Njenge- doxylamine , isithako sepilisi esilalayo eNyquil nase-Unisom, i-diphenhydramine imithi yokulwa ne-antihistamine. Kungasiza ekunciphiseni izimpendulo ze-allergenic. Ibuye ivimbele izindlela ze-histaminergic ebuchosheni. Lezi yizinyathelo ezithatha ukusuka ebuchosheni bebuchopho kuze kube yilo lonke ubuchopho. Bakha ukuvuka. Ngakho-ke, imithi evimba imigwaqo ingabangela ukulala.
Ingabe I-Diphenhydramine Isebenza Ngokufanele Ukwelashwa Ukulele?
Ukusebenza kwe-diphenhydramine akufundiwe kahle. Kunobunye ubufakazi bokuthi, uma isetshenziswe esikhathini esifushane (ngaphansi kwamasonto amabili), i-diphenhydramine ingase ithuthukise ukuqhubeka nokulala. Ngamanye amazwi, kubonakala sengathi kunokuvuswa okumbalwa ebusuku. Ngezinye izikhathi lokhu kulinganiswa ngomqondo okuthiwa ukulala kahle .
Ukulala kahle yilapho inani eliphelele lokulala lihlukaniswe isikhathi esiphelele esichitha embhedeni. Njengoba kubikwa abantu abasebenzisa imithi, kubonakala sengathi kuthuthukiswa.
Isikhathi esithatha ukulala (esibizwa ngokuthi ukulala kwesibindi ) noma inani eliphelele lokulala esilinganisweni akubonakali ukuthuthukisa ngendlela efanayo. Lokhu kungahle kubhekane nesikhathi esithathayo sokuba imithi iqale ukusebenza futhi ukuthi ihlala isikhathi esingakanani emzimbeni. Ngokuvamile, i-diphenhydramine isebenza ngamahora angu-4-6 futhi cishe ingxenye yayo isuswa emahoreni angu-4-8. Noma kunjalo, imiphumela emibi yamanzi njengobuthongo bokuhlala noma i-hangover ingenzeka, nakuba lokhu kuvame ukuthuthukiswa ngemuva kwezinsuku ezingu-4 zokusebenzisa ebusuku.
Uma kuhlolwe ngesifundo sokulala, ukulala kokulala, ukulala kahle, nokulala isikhathi esiphelele akubonisi umehluko omkhulu phakathi kwe-diphenhydramine nemifino yemvelo ebizwa nge- valerian .
Ekucwaningweni kwabantu abadala, isilingo sokuqhathaniswa nokusetshenziswa kwe- temazepam ne-diphenhydramine kubonisa ukunciphisa ukuvuswa kodwa hhayi ekuphumeni kokulala, isikhathi sokulala ngokuphelele, noma izinga lokulala nokusetshenziswa kwe-diphenhydramine. Ukubaluleka okubalulekile kule ningi ingozi yemiphumela emibi kakhulu.
Imiphumela emibi kakhulu nge-Diphenhydramine kuhlanganisa nokudemala
Kukhona ubufakazi bokuthi ukusetshenziswa kwe-diphenhydramine kubantu abadala noma asebekhulile kungabangela imiphumela emibi kakhulu.
Lezi ziphumo zingakusiza ucabange kabili mayelana nokusetshenziswa kwayo.
Okokuqala, ubani obhekwa njengomdala omdala? Ngokuvamile, lokhu kufaka abantu asebekhulile kuneminyaka engama-65. Kodwa-ke, omdala umuntu uba, ingozi enkulu yemiphumela emibi. Abadala kuphela ababhekene nemiphumela emibi njengabo bonke abanye, kepha nabo bangase bathole izinkinga ezengeziwe.
I-Diphenhydramine ibangela ukuthi kube nemiphumela emibi emibi ehlanganisa ukulala nokunciphisa izikhathi zokuphendula. Kungabangela nesizungu. Phakathi kwabantu asebekhulile abanezinye izinkinga zezokwelapha noma ukukhubazeka ngokomzimba, lokhu kungaholela ekuwa noma izingozi.
Lokhu kungenzeka uma umuntu evuka ukuchama ebusuku bese evuka.
Ama-antihistamine afana ne-diphenhydramine angaba nemiphumela ye-anticholinergic futhi. Lokhu kusho ukuthi imishanguzo isebenza ekwakheni kwamakhemikhali okuthiwa i-acetylcholine. Lokhu kungaba nemiphumela ebalulekile. Esinye esibaluleke kakhulu ukukhubazeka kwengqondo, njengokungathi kungenzeka nge-dementia noma i-delirium. Lokhu kungabonakala njengokudideka. Kukhona ubufakazi obukhulayo bokuthi ukusetshenziswa okungapheli kwala mithi kungase kuhlotshaniswe nokuthuthukiswa kwengqondo yesikhathi eside.
Kungase futhi kube "nokumisa imiphumela" njengomphumela. Lezi zingabonakalisa njengomlomo owomile, ukuqotshwa, umbono obonakalayo, nokugcinwa kwe-urinary. Ukugcinwa kwe-Urinary kungandisa ukwanda kokutheleleka kwamagciwane (UTIs) noma kuthinte umsebenzi wezinso.
Abantu asebekhulile akufanele basebenzise i-diphenhydramine uma benomlando we-glaucoma evaliwe, ukuzunywa, ukugcinwa kwamagciwane, i-asthma, noma isifo esinamandla sebindi. Kungase kube nemiphumela yesikhathi eside ememori okwandisa ingozi yokugula komqondo. Njengoba kunikezwe ingozi yeminye imiphumela emibi eyithinta ukucabanga nokulinganisela, kungase kubalulekile ukugwema ukusebenzisa i-diphenhydramine ngokujwayelekile.
Izwi elivela
Ngenhlanhla, kunezinye izinketho zokwelashwa ezitholakalayo zokuntula ukulala kwabantu asebekhulile nabantu asebekhulile. Okunye amaphilisi okulala angasetshenziswa, kepha ukwelashwa kokuziphatha kwengqondo yokungakwazi ukulala (CBTI) kungaba yindlela engcono kakhulu ngaphandle kwengozi yemiphumela emibi yemithi. Uma sikhona, i- obnetive obstructive sleep apnea kufanele ibonwe futhi iphathwe, futhi lokhu kungasiza ekunciphiseni ukuvuswa nokuphumela ubuthongo obumphumela.
> Imithombo:
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> I-Glass JR et al . "Imiphumela yokwelashwa kweviki eli-2 nge-temazepam ne-diphenhydramine kuma-insomniacs asebekhulile: ukuhlolwa okungahleliwe, okulawulwa yi-placebo." J Clin Psychopharmacol. 2008; 29: 182-188.
> Kudo Y, Kurihara M. "Ukuhlolwa komtholampilo we-diphenhydramine hydrochloride ekwelapheni kokuntula ukugula iziguli ezingokwengqondo: ukutadisha okuyimpumputhe." J Clin Pharmacol . 1990; 30: 1041-1048.
> Kryger, MH et al. "Izimiso Nemikhuba Yokulala Imithi." Elsevier , edition 6, 2017.
> Rickels K et al . "I-Diphenhydramine emndenini we-insomniac yenza iziguli: ukutadisha kabili okuyimpumputhe." J Clin Pharmacol . 1983; 23: 234-242.