Umdlavuza wesibeletho uhlobo lomdlavuza oluthinta isisu , okuyingxenye ebalulekile yesistimu yokuzala. Lo mdlavuza uvame ukuvela e- endometrium yesibeletho, okubangelwa umdlavuza we-endometrial , uhlobo oluvame kakhulu lomdlavuza wesibeletho. Ngokuvamile kakhulu, umdlavuza uqala emisipha kanye nezinye izicubu ezisekela isisu.
Uma lokhu kwenzeka, kubizwa ngokuthi i-uterine sarcoma. Amaphesenti angaphansi kwamaphesenti angu-5 ama-cancer angama-sarcomas.
Izimbangela Nezici Zengozi
Ngeshwa, asikwazi ukubona ukuthi yini ebangelwa umdlavuza we-uterine, kodwa siyazi izinto eziyingozi ezingase zenze amathuba okuthuthukisa. Umdlavuza wesibeletho uvamise ukuvela kubesifazane abasemuva-menopausal . Abesifazane abasencane bangakwazi futhi ukuthuthukisa lesi sifo, kodwa lokhu kwenzeka kaningi kakhulu.
Ezimweni ze-sarcomas ye-uterine, siyazi ukuthi ngaphambi kokuba ukwelashwa kwemishanguzo ye-radivic kungakwandisa ingozi kwabanye besifazane. Kubonakala futhi ukuthi ama-sarcomas e-uterine avela kaningi emadodeni ase-Afrika naseMelika kunaseCaucasus, nakuba isizathu asicacile.
Ngenhlanhla, siyazi kabanzi ngomdlavuza we-endometriya kunokuba senze mayelana nama-sarcomas e-uterine. Abacwaningi baye baqaphela izici eziningana eziyingozi, ezifaka:
- ungalokothi ukhulelwe
- ukuqala ukuya esikhathini ngaphambi kokuba uneminyaka engu-12, futhi uqhubeke uneminyaka engu-50 noma ngaphezulu
- unesifo sikashukela
- ukukhuluphala
- ukusetshenziswa kwe- estrogen replacement therapy (ERT)
- umlando womuntu siqu noma womndeni wesifo sebele noma se-ovarian
- ukusetshenziswa kweTamoxifen , umuthi wokwelapha umdlavuza webele
Into eyodwa yokukhumbula ngengqondo yomdlavuza wesifo sofuba yukuthi abanye besifazane abasengozini enkulu ngeke babe nomdlavuza wesifo sofuba kanti abanye besifazane abangabonakali noma yiziphi izingozi bahlakulela umdlavuza wesibeletho.
Izimpawu
Uphawu oluvame kakhulu lomdlavuza wesifo sofuba yisisu sokungena emzimbeni okwenzeka ngemuva kokuphuma esikhathini sokuya esikhathini . Ngaphambi kwalokho, ukuphuma ngegazi lomzimba kubhekwa ngokungavamile lapho:
- izinkathi zindlala futhi zinde
- Ukuphahlazeka okukhulu kwenzeka phakathi kwezinkathi
- kunenkathi engaphezu kweyodwa kwinyanga yokujikeleza
- ukuphuma kwegazi kwenzeka ngaphambi nangemva kokuya ocansini
Esinye isibonakaliso singumuthi wamanzi, udoti oluthinta igazi. Esikhathini sokuqala se-uterine sarcoma, angeke kube khona izimpawu ezibonakalayo.
Ngomdlavuza we-endometrial, uphawu oluvame kakhulu nolwazi lokuqala olunezibonela ukuphuma kwegazi elingavamile. Ezinye izimpawu zihlanganisa ukungcola kwamanzi omzimba, ubuhlungu ngesikhathi sokulala ngokocansi, nobuhlungu besisu .
Ukuxilongwa
Uma ngabe umdlavuza wesifo sofuba usolwa, ukuhlolwa okuphelele kwe- pelvic kuzokwenziwa okokuqala ngudokotela wamazinyo. Lesi yisikhathi esihle kakhulu sokuxoxa ngomlando wezokwelapha siqu nomndeni, izimpawu, nokubuza imibuzo. Uma ungenayo i- Pap smear yakamuva futhi kufanele ibe yinye, umjozi wezinzwa angase enze kanye nokuhlolwa kwe-pelvic. I-Pap smears kakhulu ayifuni ukubona umdlavuza wesibeletho, kepha enye ingenziwa ukulawula ezinye izimo zomlomo wesibeletho.
Ukuze kuqinisekiswe ukuba khona noma ukungabikho komdlavuza, i- biopsy ye-endometrial izodingeka. Lokhu kungenziwa ehhovisi likabafazi bese kuthatha isikhathi esincane sokuqedela.
Iningi labesifazane libika ukuthi lizwa ubuhlungu obulinganiselayo kanye nokuchotshozwa okugcina kuphela nge-biopsy, kanti ezinye zivele zenzeke kancane.
Enye indlela yokuthola amasampuli we-endometrial isisindo nokuhlenga (D & C). Ngesikhathi se-D & C, lesi sizalo sikholwa ngethuluzi elibizwa ngokuthi i-curette. Unikwa i-anesthetic ukuze ungazizwa noma nini ngesikhathi senqubo, kodwa ungalindela ukuchofoza kancane ngemva kwalokho.
Uma amasampula e-biopsy eveza i-sarcoma ye-uterine noma umdlavuza we-endometrial, umdlavuza usuhlelwe. Ukugxilonga kubhekisela ekutheni umdlavuza usulele kangakanani emathangeni aseduze noma ezithombeni.
Ukwelapha
Izinketho zokwelapha zixhomeke kakhulu kuhlobo kanye nesigaba somdlavuza wesifo sofuba, kodwa ukuhlinzwa kuyindlela ejwayelekile kunazo zonke zokwelashwa kuzo zonke izinhlobo.
Ukuhlinzwa kuhlanganisa:
- hysterectomy , ukususwa kokuhlinzwa kwesibeletho
- i-hysterectomy ene- salpingo-oophorectomy yamazwe amabili , ukususwa kokuhlinzwa kwesisu, ama-tublopian tubes, nama-ovaries
- i-lymph node dissection, ukususwa kwe-lymph nodes ye-pelvic phakathi ne-hysterectomy kamuva ehlolwe umdlavuza
Ukwelashwa kwezidakamizwa nakho kuyindlela yokwelapha umdlavuza wesibeletho. Lolu hlobo lwezokwelapha lusebenzisa imisebe ephezulu yamandla emisebeni yokuqeda izicubu noma ukuqeda ama-cell cell. I-radiation therapy isebenza ngokulimaza i-DNA yesifo somdlavuza, okwenza ingakwazi ukuphindaphindeka. Nakuba ukwelapha imishanguzo kungaphazamisa amangqamuzana aphilile aseduze, amangqamuzana omdlavuza azwela kakhulu emisebeni futhi efa lapho ephathwa. Amangqamuzana anempilo awonakele ngesikhathi sokushisa imisebe aqinile futhi ngokuvamile akwazi ukululama ngokugcwele.
I-Chemotherapy ingase ishiwo futhi ukuthi ilaphe umdlavuza wesibeletho kwabanye besifazane. Imithi yokwelapha i-chemotherapy isebenza ngokuqeda ngokushesha ukwanda kwamangqamuzana omdlavuza. Kodwa-ke, kunamanye amangqamuzana aphilile emzimbeni avame ngokushesha, njengezinwele zezinwele zezinwele. Ngeshwa, izidakamizwa eziningi ze-chemotherapy kungenzeka zingakwazi ukuqonda amangqamuzana amabili, ahlasele aphilile nemiphumela emibi , efana nokulahlekelwa izinwele .
Ukuvimbela
Ngenxa yokuthi asazi ukuthi yini ebangela umdlavuza wesibeletho, ukuvimbela kungaba nzima.
Siyazi ukuthi ngaphambi kokuba ukwelashwa kwama-radiation kungakwandisa ingozi ye-sarcoma ye-uterine, kodwa akufanele kugwenywe ngenxa yokuvimbela umdlavuza wesibeletho.
Njengoba sazi okwengeziwe ngalokho okwandisa ingozi yomdlavuza we-endometrial, izindlela zokunciphisa ingozi ziningi kakhulu. Ukusebenzisa isikhathi eside isikhathi sokubeletha ngomlomo nokulondoloza isisindo esinempilo kuzo zonke izindlela zokunciphisa ingozi yokuthuthukisa umdlavuza we-endometrial. Ngenxa yokuthi umdlavuza we-endometrial uphethwe yi-estrogen, ukusebenzisa i-hormone therapy esikhundleni sokumisa esikhathini esiqukethe umuthi we-progestin kanye ne-estrogen kunganciphisa ingozi yowesifazane. Loluhlobo lwe-hormone therapy lunemiphumela emibi, noma kunjalo, hhayi wonke umuntu.
Ngisho nomdlavuza we-endometrial, awukwazi ukugwema izici ezinobungozi ezifana nokusetshenziswa kwangaphambili kwe-tamoxifen ukuphatha umdlavuza webele. Udokotela noma isineke ngeke neze wenqabe ukusetshenziswa kwe-tamoxifen ngokusekelwe engozini encane yokuthuthukisa umdlavuza we-endometrial esikhathini esizayo. Ingozi nje ayifuni ngaphezu kwezinzuzo.
> Imithombo:
> I-American Cancer Society. Iyini i-Uterine Sarcoma? Umhlahlandlela oningiliziwe ngoJuni 2006.
> National Cancer Institute. Uterine Sarcoma. 26 Juni 2008.