Isifo se-muscle, okuthiwa i-myopathy, singase senzeke ngenxa yokuba ne-thyroid engasebenzi (okuthiwa i-hypothyroidism) noma i-thyroid engasebenzi (ebizwa nge-hyperthyroidism).
Izindaba ezinhle ukuthi izimpawu ze-myopathies ehlobene ne-thyroid, ezifana nobuhlungu be-muscle, ubuthakathaka, noma ukuqina, ngokuvamile zilula futhi zinciphisa ngokuphathwa okusheshayo kwesifo se-thyroid. Lokho kusho ukuthi ezimweni ezincane kangako, ukuzamazama komuntu okuhlobene nesifo sabo segciwane kungaba nzima futhi kube nzima.
Ngokuthola ukuqonda kangcono izimpawu ze-muscle zesifo se-thyroid (futhi ukuthi bazofinyelela kanjani futhi baphathwe udokotela wakho), ungathemba ukuthi uzofika phansi ekuhluphekeni kwakho kanye / noma ubuthakathaka.
I-Hypothyroid Myopathy
Izimpawu
Ubuthakathaka obunamahloni, ama-aches, kanye nokwahlukana kuvamile kubantu abane-hypothyroidism. Ngenkathi ubuthakathaka bungaba khona jikelele, abantu bavame ukuyizwa emisipha eseduze nakakhulu emzimbeni wabo, njengethanga noma ehlombe . Lokhu kungaholela ezinkingeni ezikhuphuka izitebhisi noma zihlanganise izinwele zakho.
Ngaphandle kwezimpawu zomzimba, umuntu angase abe ne-creatinine kinase (CK) ephakeme ekuhlolweni kwegazi. I-Creatinine kinase iyi-enzyme ye-muscle eyenza ukulimala kwemisipha. Ngokuthakazelisayo, izinga le-CK alixhumanisi nobuhlungu bomzimba womuntu.
Ngokuvamile, ukubonakaliswa okukhulu kwemisipha kusuka ku-hypothyroidism kungase kuthuthuke. Esinye isibonelo yi-Hoffman's syndrome lapho umuntu ehlakulela khona imisipha yomzimba (imisipha ekhulisiwe) eholela ekuqineni komzimba, ubuthakathaka nobuhlungu obukhulu.
I-rhabdomyolysis (uma imisipha iphuka ngokushesha) yinye ukubonakaliswa okungavamile kwe-muscular of hypothyroidism. Ngokuvamile kubangelwa ukuhlanganiswa kokuba i-hypothyroid ngokuzivocavoca ngamandla noma ukuthatha isimiso (imithi ye-cholesterol-ukwehlisa imithi).
Isizathu
Nakuba imbangela eqondile ye-hypothyroidism-i-myopathy eyenziwe ingacacile, abanye ochwepheshe bacacisa ukuthi ukwehluleka kwe-thyroxine (T4) ebonwe ku-hypothyroidism kuholela ekusetshenzisweni kokusebenza okungejwayelekile kwe-oxidative, okuyinto ekugcineni kudala ukulimala kwemisipha nokukhubazeka komzimba.
Ukuxilongwa
Ukuxilongwa kwe-hypothyroidism-i-myopathy eyenziwa yi-clinical, okusho ukuthi udokotela wakho uzoyilinganisa ngokusekelwe ezimpawu zakho nokuhlolwa kwangokwenyama. Ukuhlolwa kwegazi ukukala i-creatinine kinase kuzokwenziwa futhi.
Udokotela wakho angancoma ezinye izivivinyo, njenge-electromyography noma i-biopsy ye-muscle, ukulawula ezinye izimo, ikakhulukazi uma izimpawu zakho zinzima.
Ukwelapha
Qinisekisa ukuthi i-hormone ye-thyroid esikhundleni se- Synthroid (levothyroxine) ingavame ukuthuthukisa izimpawu zomzimba, njengama-cramps nokuqina, nakuba lokhu kuthuthukiswa kungathatha amasonto. Ubuhlungu besisu obuthakathaka ngokuvamile buthatha isikhathi eside ukuxazulula, njengezinyanga ezimbalwa.
I-Hyperthyroid Myopathy
Izimpawu
Ubuthakathaka besisu bungakhula kubantu abane-hyperthyroidism. Ngenxa yobuthakathaka, umuntu angase abe nobunzima ukukhuphuka izitebhisi, ephuma esihlalweni, ephethe noma ephethe izinto, futhi afinyelele izingalo zawo ngaphezu kwekhanda lawo. Ngokuvamile, ngokusuka emoyeni okuvela ku- hyperthyroidism , imisipha ethintekile ingabandakanya nalabo abakusiza ukugwinya nokuphefumula.
Kuyathakazelisa ukuthi ngenkathi ama-cramps kanye nama-aches angama-muscle angase avele, awavamile njengoba esesimweni sengqondo esithinta i-hypothyroidism.
Izinga le-creatinine kinase egazini ngokuvamile livamile, naphezu kweqiniso, kukhona ukulahleka kwemisipha.
Njengokwenyama-hypothyroidism-induced stimulation, inombolo ayihambisani nokuqina kwempawu zomzimba zomuntu.
Isizathu
Njengesifo se-muscle ku-hypothyroidism, "kungani" ngemuva kwe- myopathy ku-hyperthyroidism futhi akucacile. Kungenzeka ukuthi izinga eliphakeme lamahomoni wegciwane emzimbeni lifaka ngokuqondile. Ngokuqondile, lamazinga e-hormone ephezulu wegciwane angaholela ekwenzeni ukwanda kwamaprotheni ukubola nokusetshenziswa kwamasipha.
Ukuxilongwa
Njengawe-myopathy ku-hypothyroidism, udokotela wakho uzokwenza ukuhlolwa ngokomzimba futhi akubuze imibuzo ehlobene nezimpawu zakho zomzimba. Angase futhi ahlele ukuhlolwa kwegazi, ikakhulukazi iphaneli yomsebenzi we -roid, futhi uncoma i- electromyography .
Ukwelapha
Ukwelashwa kwe-hyperthyroidism yakho kuzokwelapha ukuphelelwa yisifo; Kodwa-ke, kungathatha isikhathi, kuze kube izinyanga eziningana okungenzeka, ngisho nangemva kokuba i-thyroid ibuyele esimweni sayo esivamile.
Izwi elivela
Umlayezo wokuthatha ekhaya lapha wukuthi izikhalazo ze-muscle zivame ukwanda kwezifo ze-thyroid futhi ngokuvamile zingancishiswa ngokujwayelekile kwemisebenzi yakho ye-thyroid.
Noma kunjalo, kubalulekile ukubona udokotela wakho uma ubona ubuhlungu obuthakathaka noma obuthakathaka obukhulu noma obuthakathaka. Ngenkathi isifo sakho se-thyroid singase sibe yikhomba, kunezinye izimo zezempilo ezingabangela izimpawu zomzimba, futhi lezi zimo zidinga uhlelo oluhlukile lokulashwa.
> Imithombo:
> Kim TJ et al. Icala le-myopathy ye-thyrotoxic enohlobo olwedlulele lwe-2 fiber predominance. Exp Neurobiol . 2013 Sep; 22 (3): 232-34.
> Miller ML, uRubin DI. (2017). I-Hypothyroid myopathy. Aminoff MJ, Shefner JM, Ross DS, ama-eds. Kusesikhathini. Waltham, MA: UpToDate Inc.
> Sindoni A, Rodolico C, Pappalardo MA, Portaro S, Benvenga S. Hypothyroid myopathy: Isingeniso esibalulekile sokwelashwa kwe-thyroid: Ukubukeza izincwadi. I-Rev Endocr Metab Disord . I-2016 Dec; 17 (4): 499-519.
> Villar J, Finol HJ, Torres SH, Roschman-Gonzalez A. Myopathy ngeziguli ezinezifo zikaHashimoto. Umtholampilo wezokutshala 2015 Mar; 56 (1): 33-46.