I-Treatment of Acid Reflux, i-Ulcers, ne-Esophagitis
I-Prilosec (i-omeprazole) i-proton-pump inhibitor (i-PPI) esetshenziselwa ukuphatha izilonda zesisu esiswini, izilonda ze-duodenal, isifo se-reflux se-gastroesophageal GERD ), kanye nesifo se- ooproperitis . I-Prilosec isetshenziselwa ukuphatha i- H. pylori (ibhethri ejwayelekile yesifo esilonda). U-Prilosec wayengumuthi wokuqala ovela kulolu hlobo lwemithi futhi uphinde wabiza igama lakhe elivamile, i-omeprazole.
Kuvunyelwe ukwelashwa kwesifo senhliziyo okwenzeka izikhathi ezingaphezu kwezingu-2 ngeviki. Ezinye imithi efana ne-PPI ihlanganisa i-Prevacid (lansoprazole), i-AcidpHex (i-rabeprazole), i-Protonix (i-pantoprazole), ne-Nexium (esomeprazole). Akubonakali umehluko omkhulu ekuphumeleleni kunoma yimaphi ama-PPI ahlukene emakethe.
Ucwaningo oluthile lubonisa ukuthi imithi efana ne-Prilosec inikeza ukuphumula okungcono nokuphulukiswa okuphelele emonakalweni we-acidic kune-H2-ukuvimbela imithi efana ne-Pepcid ne-Zantac. Lokhu kuyiqiniso kokubili ukuvuvukala okwenyukayo nokungapheli okwesibindi sakho, isisu, nesisu sakho. Noma kunjalo, udokotela wakho angase futhi ancoma i-H2-blocker uma une-reflux yesikhathi sokuhlwa esingalawulwa ngu-Prilosec.
Indlela Prilosec isebenza ngayo
Ama-proton pump inhibitors afana no-Prilosec asiza ukuvimbela amangqamuzana amathumbu ekukhiqizeni i-asidi esiswini. Ukwenza kanjalo ngokuvimbela i-enzyme evumela i-asidi ukuba ikhishwe ku-pumpton ye-proton kumaseli we-parietal esiswini.
I-Prilosec ivimbela i-asidi eningi kakhulu ekukhululweni okungabangela ukulimaza izicubu ezihlanganisa isisu, isisu, kanye namathumbu akho. I-Prilosec izoqala ukusebenza phakathi kwamaminithi angu-30 namahora angu-3.5.
Indlela Eyithathwa ngayo
I-Prilosec kufanele ithathwe ngaphambi kokudla; mhlawumbe ngaphambi kokudla kwasekuseni. Ama-capsules kufanele agonywe ngokuphelele futhi angahloliwe.
Uma unenkinga yokugwinya, okuqukethwe kwe-Prilosec capsule kungaxubene nama-appleauce noma izinto ezifanayo. Qinisekisa ukuthi ama-pellets atholakele ngaphakathi kwe-capsule awachotshoziwe noma ahloliwe uma egwinya.
Amanani asejwayelekile afaka 20mg kanye ngosuku, 40mg kanye ngosuku, futhi 60mg kanye ngosuku. Kodwa-ke, udokotela wakho angakucela ukuthi uzame kabili ngosuku uma uthola ukukhululeka kwesimiso emini kodwa ujabulele isikhathi se-acid reflux. Kubalulekile ukuthi ulandele ama-oda wakho odokotela ngokulandelela, njengoba i-Prilosec engaphezulu engalingani nemiphumela engcono.
Imiphumela emibi
I-Prilosec ivame ukubekezelela kahle ngemiphumela emibi kakhulu. Kodwa-ke, uma wenza imiphumela emibi yecala, nansi imiphumela emibi kakhulu evamile (efakwe ohlwini lokusabalalisa):
- ikhanda - ingozi engu-7%
- ubuhlungu besisu - ingozi ye-5%
- isicanucanu - ingozi engama-4%
- isifo sohudo - ingozi ye-4%
- ukuhlanza - ingozi ye-3%
- flatulence - 3% ingozi
Ngaphansi kwalokho ungase ube nesifo sokuguqula i-asidi, ukutheleleka okuphezulu kokuphefumula, ukuqunjelwa , isizungu, ukuqhuma, ubuthakathaka, ubuhlungu bokubuyela emuva nokukhwehlela. Kufanele ubone udokotela ngokushesha uma ubona izimpawu ezilandelayo, okungenzeka zihlobene nokuphendula okweqile :
- ukuqhuma, ukuvuthwa, noma ezinye izimo zesikhumba
- ubunzima bokuphefumula
- isondo
- ubunzima bokugwinya
Ukuzibandakanya Neminye Imithi
Kumele uthintane nodokotela wakho uma uthatha noma yimiphi imithi elandelayo njengoba ingakwazi ukuxhumana noPrilosec. Njengoba lolu hlu lungaphelele, kufanele njalo uxhumane nodokotela wakho ngaphambi kokuqala imithi emisha. Udokotela wakho noma u-pharmist angakwazi ukugijima isheke lokusebenzisana phakathi kwemithi enqunyiwe.
- i-warfarin
- ketoconazole
- i-ampicillin
- I-Valium
- phenytoin
- I-Antabuse
- i-cyclosporine
- I-Prograf
- I-Plavix
- Atazanavir
- Wort St. John's Wort
- I-Methotrexate
Xhumanisa ku-Bone Fractures
I-Prilosec namanye ama-proton-pump inhibitors (i-PPIs) ahlanganiswe nengozi eyengeziwe yamathambo, okuhlanganisa ukuhlukunyezwa kwesibindi, umgogodla, kanye ne-hip.
Inombolo ephakeme kunazo zonke zezinkinga ezinjalo zenzeka kubantu abathatha lezi zidakamizwa ngamazinga aphezulu ngonyaka noma ngaphezulu. Sicela uqaphele ukuthi ama-PPI angaphezu kwamakhompiyutha ahloselwe ukuthi athathwe amasonto ambalwa kuphela, futhi ngaphansi kokuqondiswa udokotela. Uma udinga le mithi isikhathi eside, kufanele uxoxe ngemithi eqhubekayo nodokotela wakho.
Ngaphambi kokuthatha i-Prilosec
Ngaphambi kokuqala u-Prilosec, buza udokotela wakho. I-Prilosec ayilona izimpawu ezinzima (izimpawu ezenzeka khona manje) zokugubha. Kunalokho, lisetshenziselwa ukuxazululwa kwesikhathi eside kwezimpawu.
Uma unezihlalo ezimnyama noma igazi elibomvu elimhlophe ezitsheni, kufanele ufune ukunakekelwa kwezokwelapha kunokusebenzisa i-Prilosec. Uma ukhulelwe, uhlela ukukhulelwa noma ukondla umntwana, kufanele uxhumane nodokotela wakho ngaphambi kokuthatha i-Prilosec. Ngaso sonke isikhathi ube nodokotela noma wezemithi ubuyekeze uhlu lwakho lwemithi lwamanje ngaphambi kokuqala imithi emisha.
> Imithombo:
> AstraZeneca. U-Prilosec Uchaza Ulwazi. https://www.azpicentral.com/prilosec/prilosec.pdf . Kubuyekezwe u-December 2016. Kufinyelelwe ngoJulayi 2, 2017.
> Katz, PO, Gerson, LB, & Vela MF. (2013. Ukuhlonza nokuphathwa kwezifo ze-reflux ze-Gastroesophageal Am J Gastroenterol 108: 308-328.
> McDonagh, MS, Carson, S & Thakurta. (2009). Ukubukezwa KweSigaba Sezidakamizwa: Final Final Inhibitors Final - Report Update 5. Oregon Health & Science University.
> Omeprazole. Iwebhusayithi ye-Medline Plus. http://www.nlm.nih.gov/medlineplus/druginfo/meds/a693050.html. Ibuyekezwe ngo-Julayi 15, 2016. Ifinyelele ngo-2 Julayi, 2017.