Leli Antibiotic Ngesinye isikhathi lisetshenziswa ukuphatha i-IBD noma i-Pouchitis
I-Ciprofloxacin uhlobo lwama-antibiotic asetshenziselwa ukuphatha izinhlobo eziningana zezifo. Kuseklasini lama-antibiotic ebanzi ebizwa ngokuthi i-fluoroquinolones. Loluhlobo lwemithi elwa namagciwane lisetshenziselwa ukuphatha izifo zombili ngamagciwane angama-gram-negative ne-gram-positive.
Ama-antibiotic kufanele asetshenziswe kuphela uma edingeka ngokucacile ngenxa yobungozi bemiphumela emibi futhi ngenxa yobungozi bokudala amabhaktheriya anqanda ukulwa namagciwane.
Imiphumela emibi ye-ciprofloxacin iyashintsha kakhulu futhi izohluka kusuka komunye nomuntu. Ezimweni eziningi, abantu abathatha i-ciprofloxacin abanayo imiphumela emibi kakhulu yokuthatha lesi sidakamizwa.
Isexwayiso se-Black Box
I-Ciprofloxacin inesixwayiso "sebhokisi elimnyama" njengoba kunikwe amandla yi-Food and Drug Administration (FDA). Isexwayiso sebhokisi elimnyama lifakwe esikhwameni solwazi lesiguli sesidakamizwa lapho kunqunywa ukuthi kukhona okungenzeka kube nomthelela obi kakhulu. Isixwayiso sebhokisi elimnyama ciprofloxacin sibhekene ne- tendonitis ne-tendon rupture. Uma uthola izimpawu ze-tendinitis, funa ukunakekelwa ochwepheshe bezokwelapha bese uxhumane nodokotela oye wachaza i-ciprofloxacin ukuthola ukuthi ungaqhubeka kanjani.
I-fluoroquinolones, kuhlanganise ne-CIPRO®, ihlotshaniswa nobungozi obandayo be-tendinitis ne-tendon rupture kuwo wonke ubudala. Le ngozi isanda kakhulu kwiziguli ezindala ngokuvamile ezingaphezu kweminyaka engama-60 ubudala, kwiziguli ezithatha izidakamizwa ze-corticosteroid, nasezigulini ezinezinso, izinhliziyo zenhliziyo noma zamaphaphu ...
Ama-antibiotics ne-IBD
I-Ciprofloxacin ngezinye izikhathi isetshenziselwa ukwelapha isifo sikaCrohn nokuphatha i- puchitis kubantu abaye bahlinzwa ngokuhlinzwa kwe-j-pouch (i-poal-anal anal anastomosis, noma i-IPAA) ukuze baphathe isifo sabo se- ulcerative colitis . Ama-antibiotic kufanele asetshenziswe njalo ngokucophelela, kodwa kufanele kuqashwe abantu abaningi abaye bathola ukuthi banezifo zesifo sofuba (IBD) ngenxa yengozi yokuhuda kanye nobungozi bokutheleleka okwesibini ngebhetri okuthiwa iClostridium difficile (noma iC difficile ) .
Abantu abane-IBD bangase babe engozini enkulu yokuba ne-flare-up yalesi sifo ngemuva kokuthatha ama-antibiotic.
Isexwayiso seNerlogical and Central Nervous System
Ngo-May ka-2016, i-FDA yakhipha izixwayiso ezengeziwe mayelana nemiphumela ethile ehlotshaniswa ne-ciprofloxacin, kuhlanganise nalabo abangathinta ama-tendon, imisipha, amalunga, izinzwa, kanye nesistimu enkulu yezinzwa. Kukhona ukukhathazeka ngalolu phiko lwe-antibiotic olusetshenziselwa ukwelashwa kwelayini lokuqala ngezifo ezinzima. Ngamanye amazwi, i-FDA icela odokotela ukuba bayeke ukubeka lesi sidakamizwa ngokutheleleka okulula, njengokutheleleka kwamagciwane, uma omunye umuthi wezokwelapha ongenawo ukukhathazeka kokuphepha ungasetshenziswa esikhundleni salokho.
Ngokusho kwe-FDA, ezinye zezinkinga eziye zachazwa njengezihlobene ne-ciprofloxacin zihlanganisa "ubuhlungu be-tendon, obuhlangene nobuhlungu be-muscle," izikhonkwane nezinaliti "ukucabangela noma ukuzwa, ukudideka nokucabangela." Lezi zingozi, noma yimuphi omunye umphumela omubi wokukhathazeka kufanele zibikwe kudokotela ngokushesha, njengoba isidakamizwa singadinga ukumiswa.
Imiphumela Ejwayelekile Ejwayelekile
Hlola nodokotela wakho uma ngabe yimiphi imiphumela emibi elandelayo iqhubeka noma ihlupha:
- isisu esithukuthele (omnene)
- isifo sohudo (omnene)
- ukuhlanza
- ubuhlungu besisu
- ikhanda
- ukuphumula
Izingcingo ezingezansi ezivamile noma ezinzima
Hlola nodokotela wakho uma ngabe yimiphi imiphumela emibi elandelayo iqhubeka noma ihlupha:
- shintsha ngomqondo wokunambitha
- ukuzwela kwesikhumba ekukhanyeni kwelanga
Njalo Yazisa Udokotela Walezi Imiphumela Ezimbi
Okungajwayelekile
- ukubhoboza isikhumba
- inzwa yesikhumba esivuthayo
- ukuhlunga isikhumba, ukuqhuma, ukubomvu, noma ukuvuvukala
Akuvamile
- ukuqhuma kwesikhumba
- itching
- imihlathi
- kunzima ukuphefumula noma ukugwinya
- ukuvuvukala kobuso noma umphimbo
- ukuphuka kwesikhumba noma amehlo
- umchamo omnyama
- izigqoko ezibomvu noma ezimnyama
- igazi emcinini
- ukukhathala okungavamile
- ukushisa kwelanga noma ukuphuza
- ukuhlukunyezwa noma ukuxubana
- ukutheleleka kwesisu
- izinguquko zombono
- ubuhlungu, ukuvuvukala noma ukwephuka kwethenda
Ezinye imiphumela emibi engabhalwanga ngenhla zingase zenzeke kwezinye iziguli. Uma ubona noma yimiphi imiphumela, hlola nodokotela wakho. Lolu lwazi luqondiswa kuphela njengeseluleko - njalo uxoxe nodokotela noma wemithi ukuze uthole ulwazi oluphelele mayelana nemithi yokwelashwa.
Umthombo:
I-Bayer HealthCare Pharmaceuticals. "EmaKholeni nasePilloxacin (Cipro) isiguli." Bayer HealthCare Pharmaceuticals Inc. Okthoba 2008.
Crohn's & Colitis Foundation of America. "Ama-antibiotics." CCFA.org. 22 Mashi 2011.
> Ukuphathwa Kwezokudla Nezidakamizwa zase-US. "Ukuxhumana Kokuphepha Kwezidakamizwa ze-FDA: I-FDA iluleka ukuvimbela ukusebenzisa i-fluoroquinolone yokulwa namagciwane ngezifo ezithile ezingaqondakali; ixwayisa ngokukhubaza imiphumela emibi engenzeka ndawonye." FDA.gov. 7 Mashi 2018.