Amanye ama-antibiotics angabangela ukumisa okulula noma ngisho nokunye ukutheleleka
Ngezinye izikhathi ama-antibiotic ayadingeka ukuze aphathe izifo ezibangelwa amagciwane. Kodwa-ke, kwezinye izimo, ukuthatha imithi yama-antibiotics ukuphatha ukutheleleka kwamagciwane, ukutheleleka indlebe, noma i-pneumonia kungaba nomthelela ongalindelekile futhi ohlala njalo. Ingabe ama-antibiotics angabangela isifo sohudo futhi kungani kwenzeka?
Kungani Ama-Antibiotics Adala Umhudo?
Into yokuqala yokuqonda ngamabhaktheriya emizimbeni yethu ukuthi akusiyo yonke "embi." Labo abangela ukuba sibe nezifo ezilimazayo yilokho esingasifuni.
Kodwa eqinisweni, umathumbu omkhulu uqukethe inombolo ephezulu yezinhlobo "ezinhle" zebhaktheriya. Lokhu yi-bacteria okumele ihlale khona, futhi kuyadingeka ukugaya kahle. Lawa ma-bacteria aphula ukudla futhi asize ukugaya. Ngaphandle kwalo, ukugaya akuhambanga kahle.
Ama-antibiotics abulala wonke amabhaktheriya
I-antibiotic ayikwazi ukutshela umehluko phakathi kwama-bacterium asiza umzimba kanye nama-bacteria okulimaza umzimba-abulala noma yiluphi uhlobo lwebhaktheriya alutholayo. Uma ezinye zebhaktheriya ezinomsoco eziphilayo ezihlala emathunjini amakhulu zibulawa, ibhalansi yebhaktheriya emihle / embi iphazanyiswa. Ngaphandle kwazo zonke izimbungulu ezinhle ukwenza ukugaya, isifo sohudo noma izihlalo ezivulekile kungaba umphumela.
I-Clostridium difficile: Uhlobo Olunye Lwabhaktheriya Okubi
Sidinga ama-bacteria azuzisayo kumgudu wethu wokugaya, kodwa lokho akusho ukuthi wonke amabhaktheriya ahlala lapho enza umsebenzi omuhle emizimbeni yethu. Kukhona namabhaktheriya awonayo ahlala egazini lokugaya.
Izindaba ezinhle ukuthi isikhathi esiningi, izinkinga ezinhle zamabhaktheriya ziwashaya emuva amabhaktheriya ayingozi, ukugcina izinto ezimbi bese zivimbela ukuthi zingabangela izifo.
Wonke umuntu unezihlukumezi ze-bacteria, futhi isikhathi esiningi azenzi lutho, kodwa ukuthi zonke izinguquko ngemuva kwemithi elwa namagciwane lapho kubulawa khona amagciwane.
Ku-1% kuya ku-2% wabantu, uhlobo olulodwa lwamabhaktheriya anobungozi ahlala ekoloni- i- Clostridium difficile- angaqala ukuphindaphinda futhi athathe ikoloni ngemva kwemithi elwa namagciwane. Lokhu kungaba ngeshwa kubangele ububanzi bezinkinga zezokwelapha ezibandakanya:
- Ihudo elidakayo-elihlanganisiwe
- I-colitis (ukuvuvukala okujwayelekile kolononi)
- I-colitis epseudomembranous
- I-megacolon enobuthi , esiphuthumayo esiphuthumayo sokuhlinzwa
Imiphi Antibiotics Engabangela Izinkinga?
Noma yikuphi ukulwa namagciwane kungaphazamisa umthamo emathunjini amakhulu futhi kuholele amabhaktheriya abulawe lapho. Kodwa-ke, akuwona wonke uhlobo lwemithi elwa namagciwane ephethe inani elifanayo lokufaka isandla ku- C difficile colitis. Yiqiniso kuyilapho ukuthatha noma yiliphi i-antibiotic kungaholela ku- C difficile colitis, kunezinye antibiotic ezinomngcipheko omkhulu wokwenza kanjalo kunabanye.
Ama-antibiotic amaningi aphethwe yi- C difficile colitis yizona ezakhiwa ukubulala izinhlobo eziningi zamabhaktheriya, okungaqondakali, ngoba zizoba nomthelela ezinhlobonhlobo ezahlukene zebhaktheriya, kufaka phakathi okuhle. Ama-antibiotics amaningi ahlotshaniswa ne- C difficile colitis yilezi:
- ama-antibiotic amaningi (i-clindamycin, i-cephalosporins [cephalexin], i-fluoroquinolones),
- i-penicillin ebanzi (i-ampicillin, i-amoxicillin)
Imithi elwa namagciwane ephethe ingozi elinganiselayo ihlanganisa:
- imipenem
- tetracyclines
- macrolides
- i-sulfa-trimethoprim
Lawo ma-antibiotic anengozi ephansi kakhulu:
- metronidazole
- vancomycin
- aminoglycosides
- i-sulfa
- nitrofurantoin
- linezolid
Ingabe Usizo Lwe-Probiotics Lungavimbela Ukuhuda?
Ama-probiotics atholakala kakhulu ezitolo ezinkulu nezitolo kodokotela kodwa akuzona zonke ezidalwe ngokulinganayo. Zingase zibe nezinhlobo ezahlukene zebhaktheriya kanye namanani ahlukene, futhi ikakhulukazi azilawulwa, nakuba zikhona ezinye izinto ezinokwethenjelwa kunabanye. Ngaphezu kwalokho, akakaqali ukuthi yiziphi ezingasiza, noma ngabe zingakanani okufanele zithathwe.
Ngakho-ke, akukho zincomezelo zokugqoka mayelana nokuthatha ama-probiotics emva kwe-antibiotics. Kunconywa ukuthi ngesinye isikhathi i-probiotic ingasiza, kodwa ngeke ibe yiqiniso kuzo zonke izimo, futhi izindleko zama-probiotics kanye nokulimala okungaba khona okumele zenzeke nazo kufanele zicatshangelwe.
Kubantu abanesifo sofuba (IBD) , ikakhulukazi labo abane-ostomy noma i- j-poch , kubalulekile ukukhuluma nodokotela we- gastroenterologist mayelana nama-antibiotics. Ama-antibiotics ahlotshaniswa nama-IBD-ups, futhi i-gastroenterologist ingaba nokusikisela ukuthi ngabe i-probiotic ingaba usizo, nokuthi yiliphi igama elizolisebenzisa.
Izwi elivela
Ukutheleleka kwamagciwane kungadinga ukuphathwa ngama-antibiotics, futhi kungenzeka kube khona indlela yokuyithola. Ukukhethwa kwama-antibiotic asetshenzisiwe ngeke kusekelwe noma ngabe kunomthelela ophansi we- C difficile colitis, kodwa kunalokho okukhethayo ngokubulala amabhaktheriya abangela ukutheleleka. Uma sekuqalile ukuthi imithi ye-antibiotics iqalile, kudinga ukuqedelwa ukugwema ukudala izinkinga zama-antibiotic-resistant bacteria.
Uma unenkinga mayelana nezinkinga zokuhuda ngemuva kokuthatha ama-antibiotics, khuluma nodokotela wakho. Kwezinye izimo, kunendlela ethile yokulwa nayo, kodwa kufanele iphumelele ngokumelene nama-bacteria abangela ukutheleleka. Ukuthatha ama-probiotics kungaba yindlela yokuphindaphinda ikholoni ngamabhaktheriya amahle, kodwa lokho kufanele kukhulunywe nodokotela, ngoba futhi, kufanele futhi bakhethe.
Imithombo:
> I-Issa I, uMoucari R. "Ama-probiotics for isifo sohudo ehlobene namagciwane: Ingabe sinesibopho?" I-World J Gastroenterol. 2014 Dec 21; 20: 17788-17795.
I-Sachar DB, i-Walfish AE. "I-Clostridium difficile-I-Colitis Yenzelwe." I-Merck Manual. Sep 2006.
Schroeder MS. "I-Clostridium difficile - isifo sohudo ehambisanayo." Am Fam Physician . 1 Mashi 2005.