Ekuboneni kokuqala, i-lymphoma ne-lymphedema ngamagama abonakala sengathi angahlobene, kodwa abhekisela ezimweni ezihluke kakhulu. I-lymphoma ingumdlavuza wamangqamuzana egazi amhlophe lapho i-lymphedema iqoqa uketshezi, noma i-lymph, ezitokisini ezithambile ezihambisana nokuvuvukala. Ngokuvamile umuntu uthola i-lymphedema njengengalo evuvukile noma umlenze.
I-Lymphedema ivame ukubangelwa ukususwa noma ukulimaza ama-lymph nodes akho njengengxenye yokwelashwa komdlavuza. Ngenxa yokuthi umdlavuza webele usondelene kakhulu nezinye i-cancer, ososayensi banolwazi oluthe xaxa mayelana ne-lymphedema emdlalweni webele; Kodwa-ke, i-lymphedema ingenzeka kulabo abasinda kancelisi yazo zonke izinhlobo ezahlukene, kuhlanganise nezinhlobo ezahlukene ze-lymphoma . Inani labantu abane-lymphedema kulindeleke ukuba landa kakhulu eminyakeni eyishumi ezayo noma ngaphezulu ngenxa yezinga eliphezulu lokusinda ngokulandela ukwelashwa komdlavuza.
Izimbangela
I-lymphatic system ifana nesistimu yokujikeleza ehamba phambili: iqoqa uketshezi emathisini omzimba futhi iyayifaka emithanjeni yakho. Uhlelo lwama-canals, oluhlangene ndawonye ngama-lymph nodes, lunezindawo ezihlukene noma "iziphathimandla." Ngokwesibonelo, ama-lymph nodes endaweni yokugaya aphethwe ukukhipha nokuhlunga izicubu zamanzi kanye ne-lymph emilenzeni, kuyilapho lezo zinhlanzi zisezintweni zisiza gxuma bese uhlunga i-lymph ephuma ezandleni.
Uma kukhona okuvimbela ukugeleza kwe-lymph noma okuvimbela ukuthi ingahambisani kahle, lokhu kungaholela ku-lymphedema endaweni ethile yomzimba. Uma kwenzeka izakhiwo ze-lymph in the groin, isibonelo, ukuvimbela kungabangela ukuvuvukala kwemilenze eyodwa noma zombili. Emagqumeni, emva kokuhlinzwa kanye nemisebe yomdlavuza wesifuba, kungase kube nokuhlukunyezwa noma amaqoqo ezinhlobonhlobo ezivuthayo ezivimbela ukugeleza kwe-lymph, noma i-lymphatics ngokwayo ingahle isebenze ngokulandela ukwelashwa.
Kukhona ezinye izimbangela zesandla nomlenze ukuvuvukala hhayi ngenxa ye-lymphedema, ukuqinisekisa, futhi umsebenzi wakho udokotela kulezi zimo ukukhomba inkinga engaphansi.
Izimpawu Nezinkinga
Uma ukuqoqwa koketshezi oluthe xaxa kanye namaphrotheni emahlakalweni okuqhubekayo, lokhu kungaholela ekuphenduleni okuvuthayo, ngokugcoba amafutha nokubhula, nokuvuvukala okunamandla, okunamandla kuya kweqile izingxenye zomzimba ezithintekayo. I-Lymphedema ingabangela izimpawu eziphazamisayo, njenge:
- Ukuqina kwesikhumba
- Amandla anciphisa ukuhambisa amalunga
- Ukukhulula emilenzeni ethintekile
- Ukukhathazeka nobuhlungu
- Izifo ezijwayelekile.
I-Lymphedema ne-Lymphoma
Ukulandela ukwelashwa komdlavuza, ukuvinjelwa noma ukubhujiswa kwezakhi zellymatic ngokuhlinzwa kanye nemisebe kungabangela i-lymphedema. Ukwelashwa kwe-Cancer okubandakanya i-lymph nodes kungalimaza imizila yamanzi e-lymph, okwenza ukuba i-lymph fluid iqoqe emilenzeni ehlobene nezizinda zomzimba.
Nakuba kungavamile ukubikwa njengesifo sokuveza i-lymphoma, i- lymphedema ingabangela i-lymphoma , ngokwayo, noma ukuphindaphinda kwayo. I-Lymphedema ethinta umlenze owodwa iye yabika njengesethulo esingavamile sokuqala kwe-lymphoma, ikakhulukazi kwabesifazane, futhi kaningi nge-lymph nodes evuvukalayo endaweni yokugaya noma ukulimala esiswini. I-lymphedema ngenxa ye-lymphoma ingenzeka nakwezinye izindawo, lapho ukugeleza kwe-lymph kuvinjelwe ubukhulu obukhulu, isibonelo.
Ukuphathwa
I-Lymphedema ibhekwa njengesimo esingapheliyo. Ngenkathi ikwazi ukuphathwa, ayikakabonakali njengesimo esingaphiliswa ngokucacile. Abacwaningi bazama ukuthuthukisa isimo, noma kunjalo.
Ukwelashwa okujwayelekile kwe-lymphedema yilokho owaziwa ngokuthi ukwelashwa kokuzibulala, okubandakanya ukuvivinya umzimba, ukugqoka izingubo zokucindezela, ukunakekelwa kwesikhumba kanye nokusikwa kwesikhumba kanye ne-lymph drainage.
Ngezinye izikhathi ukuhlinzwa kudingekile ezimweni ezimbi noma ezimweni ezingavumelani nokwelashwa okujwayelekile okuhlolisayo.
Ukwelapha
Kunezigaba ezimbili eziyisisekelo zokwelapha for lymphedema: ukuhlinzwa ablative / debulking kanye nokuhlinzwa / physiologic ukuhlinzwa.
Izinqubo ezithintekayo noma ezithintekayo ziye zasetshenziselwa kusukela ekuqaleni kweya phakathi nangekhulu lama-20 th . Lezi zindlela zinciphisa umthamo wezitho ezivuvukile, kodwa zingabonakaliswa ngokuhlukumeza okubanzi kanye nezinye izinkinga. I-liposuction isusa izicubu ze-adipose ukuze unciphise ivolumu yesitho, kodwa-ke, ngokuvamile kufanele usebenzise ukwelapha okucindezela impilo yonke.
Ukuhlinza okusebenzayo noma physiologic kufaka ukudlulisa i-lymph node ukudlulisa (VLNT) kanye ne- lymphovenous bypass . Lezi zindlela ziye zasetshenziswa kamuva nje, ngakho-ke kuyaziwa kangako ngemiphumela yokuqhathanisa kanye nemininingwane mayelana namasu afanele okwandisa imiphumela. Noma kunjalo, imiphumela ithembisile kuze kube manje, eyadala intshiseko. Zombili amasu azama ukuqondisa ezinye ze-fluid ezigcinwe emuva ohlelweni oluyingozi. Zombili zihlinzekwa ngokuyinkimbinkimbi ngoba zibhekwa njengezimboni ezincane, lapho kudingwa khona ukuxhumana okuncane - futhi ukuhamba ngokwemvelo kunomqondo omkhulu, yingakho ngezinye izikhathi kuchazwa ngokuthi "super" ukuhlinzwa micro.
- E-lpphovenous bypass, imikhumbi yokusebenza i-lymphatic ixhunyiwe kuminyene emincane - ukuhlinzeka okuncane okuyinkimbinkimbi okuzama ukubuyisela kabusha imishini yokubhukuda.
- Ku-VLNT, odokotela abahlinzayo bayayikhokhisa i-lymph nodes kusuka endaweni eyodwa yomzimba futhi bayigxilisa ngegazi kanye namanye amafutha azungezile endaweni ethintekayo yi-lymphedema. Kulo msebenzi wokuhlinzwa, empeleni usanda ukufakelwa kabusha.
Enye yezinto ezihlukanisayo mayelana ne-VLNT wukuthi udlulisela "isikhungo sokuzivikela esibhedlela" endaweni ewonakele - kungakhathaliseki ukuthi ngokuhlinzwa, imisebe yenye into. Kuyathakazelisa ukuthi zonke izifundo zokwelashwa kuze kube manje ne-VLNT ziye zabonisa ukuthuthukiswa kwezifo zesikhumba - ngamagama emitholampilo afana ne-erysipelas, i-lymphangitis, ne-cellulitis - ngemuva kokudluliselwa kwe-lymph node ye-vascularized.
Xhumanisa ingozi yomdlavuza
Akukho bufakazi kulokhu, kepha umbuzo othakazelisayo okwamanje kubacwaningi njengoba bezama ukuqonda ukuxhumana phakathi kwesistimu yomzimba nomdlavuza.
Ngakolunye uhlangothi, ama-lymph nodes avame ukususwa ezinhlotsheni ezahlukene zegciwane. Izinhlobo eziningi zomdlavuza ekuqaleni ziqukethe noma zisabalalisa ekukhenizeni izitho zamakhansela ngamashaneli lymphatic ngaphambi kokuba zisakaze kwezinye izingosi emzimbeni, ngakho-ke izigameko zesiguli esifundeni seziguli zomdlavuza ngokuvamile zikhishwa ngokuhlinzwa.
Ngakolunye uhlangothi, abanye abacwaningi bakhomba ukuthi i-lymph node yokuhlukanisa i-lymph node e-melanoma yezinyathelo ayikhuthazwa ngoba ayithuthukisi ukusinda. Kwezinye izimo kanye namanye ama-cancers, kungenzeka ukuthi ukukhipha izitho zamakhansela kungase kube njengabalindisango bokuzivikela komzimba, okusho ukuthi ukususwa okungadingekile kungabangela ukuhlaselwa okubi.
Ezinye ezitholakala ezifundweni zesilwane zisikisela ukuthi ukugeleza kwe-lymph kudla indima ebalulekile ekwenzeni izimpendulo eziphathelene nokudla kwamagciwane futhi ukuthi ukukhubazeka okukhulu kwe-lymphatics kungase kuqiniswe ukukhuthaza ukukhula kwezicubu eziyinhloko. Noma kunjalo, ososayensi baqala ukutadisha nokuqonda izinto mayelana "ne-microenvironment ye-tumor" ne-immunology ye-tumor, futhi lokhu kuyindawo ekhuthele kakhulu yocwaningo, enemibuzo eminingi esele.
Imithombo
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