I-Selenium ingumsoco obalulekile empilweni yakho, futhi ibalulekile ekwenzeni i-hormone metabolism ye-thyroid, phakathi kweminye imisebenzi eminingi ebalulekile.
I-Selenium iyi-mineral etholakala kokudla okunye esikudlayo, okungeziwe ekudleni ukuze kuqinisekiswe, futhi ingathathwa njengesisonge sokudla. Umzimba awukhiqizi i-selenium, ngakho-ke kuphela indlela esithola ngayo i-selenium ngokudliwa nokudla.
Izinga le-Selenium lingalinganiswa nokuhlolwa kwegazi. Ukuhlaziya izinwele kungakwazi ukuhlola amazinga ase-selenium asekude. Ngokwezikhungo zikazwelonke zezempilo, izinga le-selenium enempilo yi-micrograms ezingu-8 (mcg) / dL noma ngaphezulu. E-United States, ukuntuleka kwe-selenium akuvamile, futhi abantu abaningi bathola inani elidingekayo le-selenium.
Kunezici ezithile ezingozini zokuntuleka kwe-selenium, kufaka phakathi:
- Izinambuzane, ukugaya ukudla, noma izinkinga zokungenisa
- Ukuba nesifo sokuhlinzwa kwesisu esiswini
- Ukuhlala endaweni ene-selenium-engenamhlabathi
- Imithi ye- cholesterol -lowering statin
I-nut yaseBrazil iyaziwa ukuthi inezinga eliphezulu kakhulu le-selenium. Okunye ukudla okuvela emithonjeni ye-selenium kuhlanganisa ukudla okulwandle-okufana nezinhlanzi, ama-sardine, i-salmon, i-halibut, ne-tuna-nezinyama, izinkukhu, amakhowe, isinkwa, okusanhlamvu, okusanhlamvu, amaqanda nemikhiqizo yobisi.
I-Selenium iyatholakala njengesengezo, noma yedwa, noma ngamafomu ehlangene kuma-multivitamines.
Kunezinhlobo ezimbili ze-selenium: selenimuonine, noma selenite ye-sodium. Ucwaningo luye lwabonisa ukuthi kunokwakheka okungcono kwesimo se-selenimononine se-selenium. Ochwepheshe batusa ukuthi abantu abadala bangabi ngaphezu kuka-400 mcg we-selenium nsuku zonke kusuka kuyo yonke imithombo. Amazinga aphezulu angabangela ubuthi be-selenium, enezimpawu ezifana nezinwele nokulahleka kwe-nail, ukuhlukumeza, ukuhlukumezeka, kanye nesimiso sezinzwa ezingavamile.
Ngokuyinhloko, qaphela amantongomane aseBrazil, ngoba aqukethe selenium kakhulu-kwezinye izimo ezingaphezu kuka-100 mcg ngomuncu-ukuthi ungabangela uketshezi lwe-selenium.
Impumelelo ye-Selenium ku-Thyroid
I-thyroid iyilungu eligxilisa i-selenium ngaphezu kwanoma yiliphi elinye. I-Selenium idlala indima ebalulekile ekwenzeni ikhanda lakho le-thyroid ukukhiqiza i-hormone ye-thyroid.
Ukuntuleka kwe-selenium kuhlotshaniswa nezinkinga ezihlukahlukene ze-thyroid, kuhlanganise:
- I-Hypothyroidism
- I-subclinical hypothyroidism
- Zenza ngokuzenzakalelayo i-thyroiditis ye-Hashimoto
- I-thyroid ekhulisiwe (i-goiter)
- Umdlavuza we-Thyroid
- Isifo samathuna
Iodine-isakhiwo sokwakha kanye nesithako esiyinhloko se-hormone yegciwane-empeleni sidinga selenium ukuze kuhlanganiswe kahle i-hormone yegciwane. Ucwaningo oluthile luthole ubudlelwane obungenalutho namazinga ase-selenium kanye nengozi yakho ye-goiter (i-thyroid ekhulisiwe), kanye nokulimaza kwegciwane lakho le-thyroid kubantu abanesifo se-iodine.
Ucwaningo oluningi luye lwabonisa ubudlelwane obukhulu phakathi kokunakekelwa kwe-selenium-ngisho nalapho kungenakho ukungabi khona-nokusebenza kwegciwane. Ngokwesibonelo:
- Ucwaningo oluthile luye lwabonisa ukuthi ukwesekwa nge-selenium kunciphisa amakhemikhali e-peroxidase ye-thyroid (TPO) kanye nobukhulu bezimpawu ze-hypothyroidism.
- Ucwaningo olulodwa lwathola ukuthi 200 mcg ye-selenium enikezwa abesifazane abakhulelwe abanezinkinga ze-peroxidase (TPO) ye-thyroiditis banganciphisa ingozi ye-postpartum thyroiditis.
- Ucwaningo oluthile oluthola ukuthi ukuphatha iziguli ezinesifo somzimba we-thyroid ezincane nge-200 mcg / usuku selenium ngezinyanga eziyisithupha kuthuthukisiwe izinga lokuphila lomzimba, imiphumela eyiphuthumayo yezempilo ye-eye, futhi yanciphisa kakhulu ukuqhubeka kwezimpawu.
Ngesithakazelo esiyinhloko isifundo se-2016 esibikwe encwadini ethi Thyroid esahlaziya umthelela wokufakelwa kwe-selenium ekwandeni kwama-antibody wezinga le-Hashimoto's thyroiditis.
Ucwaningo lwahlola kokubili i- peroxidase ye-thyroid (TPOAb) ne-thyroglobulin (TgAb) ama-antibody levels ema-3, 6, nasezinyangeni ezingu-12 ze-selenium ukwesekwa ngamaqembu amabili weziguli zikaHashimoto; owathola ukwelashwa kwe-levothyroxine ye-hormone yegciwane lesandulela ngculazi, kanti enye isifo esasanda kutholakala singelashwa nge-hormone ye-thyroid.
Okutholakele kwaba mnandi kakhulu. Kulezo ziguli zikaHashimoto zelashwa i-levothyroxine nge-hormone esikhundleni salo, i-selenium supplementation yabangela amazinga we-TPOAb aphansi kakhulu ngemva kwezinyanga ezintathu, futhi lawo mazinga aqhubeka ehla ezinyangeni ezingu-6 nezinyanga ezingu-12. Ukwengeza, i-TgAb ayizange iyancipha kuze kuphele iphuzu lezinyanga ezingu-12.
Esiqenjini esingasetshenziswanga i-Hashimoto, i-selenium supplementation yabangela ukwehla kwamazinga we-TPOAb emva kwezinyanga ezintathu, kodwa hhayi ngemva kwezinyanga ezingu-6 noma ezingu-12, kuyilapho i-TgAb inciphile ezinyangeni ezingu-3, kodwa hhayi ezinyangeni ezingu-6 noma ezingu-12.
Ingabe Kufanele Ukwandisa I-Intake Ye-Selenium?
Ngaphambi kokuba ucabange ukungeza izingcosana zamantongomane aseBrazil ekudleni kwakho, noma ukuthatha i-selenium supplementation, ungase ufune ukuba namazinga akho ase-selenium ahlolwe udokotela wakho. Angabe esinikeza isiqondiso ngokuthi ungase uzuze ngokukhulisa i-selenium yakho yokudla noma ukwengeza izithako. Khumbula ukuthi ngisho noma ukhetha ukwengeza nge-selenium, kufanele ubale ukudla kwakho, futhi uqiniseke ukuthi ubala noma yiliphi selenium kuma-multivitamine nakwezinye izithako, ukuze ukudla kwakho kwansuku zonke kungadluli ku-400 mcg nsuku zonke.
> Imithombo:
> Drutel, A, Archambeaud F, noCaron P. "Selenium kanye neGland Gland: Izindaba Ezinhle Ezinhle KwabeMtholampilo." I-Clin Endocrinol ye-Endocrinology yezokwelapha 78.2 (2013): 155-64. I-PubMed. 30 Mashi 2016.
> Hu, S et al. "Izici eziningi zokudla okunomsoco kanye nengozi kaHashimoto's Thyroiditis." I-Thyroid. Mashi 2017. kufanele: 10.1089 / thy.2016.0635.
> Kafai MR, Ganji V. Ubulili, iminyaka, indawo, ukubhema, nokuphuza utshwala kuthonya i-serum selenium yokubheka eU.SA: Ucwaningo lwesithathu lwezeMpilo kaZwelonke kanye neNutrition Examination, 1988-1994. J Trace Elem Med Biol 2003; 17: 13-8.
> Niskar AS, Paschal DC, SM Kieszak, FM KM, Bowman B, Gunter EW, et al. Izinga le-serum selenium kubantu base-US: I-National Health and Nutrition Examination Survey yesithathu, ngo-1988-1994. I-Biol Trace Elem Res 2003; 91: 1-10.
> Wichman J et al. "Ukwengezwa kwe-Selenium Kwenyuka Ngokunciphisa Amanqanaba E-Autoantibody Thyroid Kwabagulayo abane-Autoimmune Thyroiditis Ezingapheliyo: Ukubuyekezwa Okuhlelekile Ne-Meta-Analysis." I-Thyroid. Umqulu 26, Inombolo 12, 2016 I-DOI: 10.1089 / thy.2016.0256