I-Singulair, i-Accolate, i-Zyflo ne-Zyflo CR iguqule ukulayishwa komkhiqizo wabo ukufaka ulwazi mayelana neminye imiphumela engaba khona yemiphumela yengqondo yengqondo eye yabonwa ngeziguli ezisebenzisa le mikhiqizo. Imicimbi ukuthi iziguli nabahlinzeki bezempilo kumele bazibandakanye zifaka:
- ukukhathazeka
- ukuhlukunyezwa
- ukukhathazeka
- ukuphupha okungajwayelekile
- izindlu
- ukucindezeleka
- ukulala
- ukucasuka
- ukuphumula
- Ukuzibulala nokuzibulala
- ukuzibulala
- ukuthuthumela
Uma ubona noma yikuphi kwalokhu nemiphumela emibi udinga ukuqinisekisa ukuthi ukhuluma ngokushesha nodokotela wakho ochaza. I-FDA inezincomo ezilandelayo ezigulini nabahlinzeki mayelana nemiphumela emibi ye-Singulair nemiphumela emibi yamanye ama-modifiers e-leukotriene:
- Iziguli nabaqeqeshiwe bezempilo kufanele bazi ukuthi kungenzeka yini imicimbi ye-neuropsychiatric nale mithi.
- Iziguli kufanele zikhulume nabahlinzeki babo bezempilo uma lezi zenzakalo zenzeka.
- Ochwepheshe bezempilo kufanele bacabangele ukuyeka le mithi uma iziguli zakha izimpawu ze-neuropsychiatric.
Ulwazi olusha lwakamuva lwemikhiqizo lungatholakala kwiwebhusayithi ye-FDA.
Ingabe Zikhona Izindlela Ezingavunyelwe Ku-Singulair?
Ngenkathi engeyona ingxenye yemihlahlandlela ye-asthma yamanje, okungenani kukhona okunye okunye okuya ku-Singulair uma uhlangabezana nemiphumela emibi noma ungafuni ukuthatha imithi.
Ngokuthakazelisayo akuyona ngisho nemithi, kodwa kunalokho ukudla kokudokotela .
Ukudla kwezokwelapha kuchazwa ngaphansi kwe-Orphan Drug Act futhi kulawulwa yi-US Food and Drug Administration (FDA). Njengoba nje kuzwakala, ukudla kwezokwelapha kuwumkhiqizo onomgomo wokusebenza njengokwelashwa ngokuwufaka njengokungathi uzodla ezinye ukudla.
Esikhundleni sokudla nje okunempilo, lezi zokudla zihlelwe ikakhulukazi ukuthuthukisa isifo. Ngokufanayo, lokhu akuyona nje ukudla ongakuthola esitolo. I-FDA ithi udinga ukuba unakekelwa udokotela futhi kudingeka ukuba akulandele njalo njengoba nje udinga ukukwenza nanoma imuphi omunye umuthi we-asthma.
Kulesi simo, i-Lunglaid yidla yezokwelapha eyenzelwe ukunciphisa amazinga e-leukotriene. Isibalo esinqunyiwe salokhu kokudla kwezokwelapha yizingane ezine- asthma ezilawulwa kahle ezingathandi noma ezingenakubekezelela i-Singulair.
Ezilingo zomtholampilo, i-Lunglaid yabonisa izinga lokuphila elihle futhi liyancipha emazingeni e-leukotriene. I-leukotriene homeostasis yabangela ukuqina kwesifuba esincane, ukukhwehlela, ukuphefumula nokuphefumula. Iziguli ezithatha i-Lunglaid zaqashelwa ukujabulela imisebenzi yasekhaya, ezemidlalo, imisebenzi yomphakathi kanye nokubhekana nokulala okungcono. Futhi, imiphumela emibi yayingeyona ejwayelekile eqenjini lezokwelapha esebenzayo kunokuba likhona eqenjini le-placebo. Izindlela zokwelapha ezimbalwa kakhulu, ngisho nalabo abanemiphumela emibi kakhulu, banomphumela ofanayo kusuka kulowo mbono.
Umthombo:
Ulwazi lwezokuphepha lwe-Post Market ye-FDA. Ulwazi olusha olusha nge-Leukotriene Inhibitors: i-Montelukast (edayiswa njenge-Singulair), i-Zafirlukast (ithengiswa njenge-Accolate), ne-Zileuton (ithengiswa njengeZyflo noZyflo CR)
Izifundo Zemitholampilo Lunglaid.