Ucwaningo lubonisa ukuthi phakathi kuka-20% no-40% wabantu abanesifo sika-Parkinson (PD) ababhekene nokuqothulwa okungathí sina (okungaphansi kwezintathu zokunyakaza kwesonto ngesonto). Izinombolo ezinkulu zabantu abane-PD ziye zahlobanisa izimpikiswano zomzimba ezifana nokubhubhisa, umuzwa wokugcwala nokucabangela. Njengoba lesi sifo siqhubeka, zonke lezi zinkinga ze-GI ziba zivame kakhulu. Ezimweni ezingavamile, izinkinga ezinkulu - ezifana ne-megacolon (ukwandiswa kolononi) kanye nokukhishwa kwe-colon - kungavela kulezi zinkinga ze-GI.
Ukuxhumana phakathi kwalaba ababili kungase kubonakale kungaqondakali emkhathini, kodwa ucwaningo lubonisa ukukhanya ngalezi zimo ezingathandeki zalesi sifo.
Ucwaningo olunzulu lwabantu abanempilo olulandelwe eminyakeni eminingana (njengengxenye ye-Honolulu Heart Study Program) lwembula ukuthi amadoda abika ukuthi banesisindo esingaphansi kwesiguli esisodwa nsuku zonke babe nobungozi obukhulu obuphindwe kabili be-P PD kunabamadoda wayenezinyathelo zansuku zonke zamathumbu; ingozi yabo yayiyizikhathi ezine eziphakeme kunaleyo yamadoda ayephethe ukunyakaza kwezinyanga ezimbili noma ngaphezulu ngosuku.
Leli gama lwedatha liye laholela abanye ukuthi basho ukuthi ukuqothulwa ukubonakaliswa kokuqala kwenqubo yesifo ngokwayo futhi kungase kulandelwe izimpawu ze-PD ngeminyaka. Ubudlelwane obubangela kanye nomphumela phakathi kokuqothulwa kanye ne-PD bucwaningwa ngentshiseko. Enye inkolelo ekhomba ukuthi indima ebangela ukuqothulwa ekuthuthukiseni kukaParkinson yukuthi uma impahla ihamba kancane ngekoloni, noma yikuphi into enobuthi ephuzwayo inesikhathi eside sokungenelela ohlelweni.
Uma isetshenziswe ngobuningi, lezi zinto ezinobuthi zingalimaza amangqamuzana akhiqiza i- dopamine , abeke umuntu engozini enkulu yama-Parkinson. Kodwa-ke, kubantu abaye babhekwa ukuthi banesifo, ukungabi namandla okwanele kwe-dopamine kungathinta ngqo imithwalo yemisebenzi (GI), ukunciphisa ukuhamba kwezinto ngokusebenzisa ikoloni.
Yini Engayenziwa Ngayo Lezizinkinga Zingajabulisi I-GI?
Ngeshwa, ukucwaninga ngezinkinga ze-GI ezihlobene ne-PD kuye kwaba bambalwa futhi kuphakathi, ngakho odokotela abanalo izindlela zokuzama nokuyiqiniso zokubhekana nazo. Ezinye izidakamizwa zokwelapha izinkinga ze-GI kubantu abangenawo i- PD azikwazi ukusetshenziselwa labo abane-PD ngoba lezi zidakamizwa (i-Metoclopramide hydrochloride) zithonya kabi izinhlelo ze-dopamine ebuchosheni.
Uma unesidingo sokubamba i-PD nesipiliyoni, kunengqondo ukuzama ukusebenzisa izindlela eziphephile nokulula ukubhekana nale nkinga ngaphambi kokuthi ungeze izidakamizwa ezintsha emgomweni wakho wansuku zonke. Ukwandisa i-fibre yokudla nokuphuza amanzi amaningi nezinye izikhukhula kuyisinyathelo sokuqala esilungele ukwelashwa. Uma udokotela wakho evuma, ungase ucabange nokuthi uthatha ama-fibre supplements, njenge- psyllium noma i- methylcellulose . Uma lezi zindlela ezilula zingasebenzi, udokotela wakho angase akucabangele ukukunika isitoreji se-stool noma i-laxative.
Umthombo:
Pfeiffer, RF (2005) Ukungasebenzi kwamathumbu emathunjini. Ku: Izifo ze-Parkinsons kanye nokungasebenzi kwamandla angekho. URF Pfeiffer nami I. Bodis-Wollmer, Eds Humana Press: Totowa, New Jersey, Pps 115-126.