Indlela i-Creutzfeldt-Jakob Izifo ezihlukana ngayo ne-Alzheimer's

Lesi Sifo Ngezinye Izikhathi Ngokwempela Sibizwa Ngokuthi "Isifo Sama-Cow"

Yini i-Creutzfeldt-Jakob Disease (CJD)?

I-Creutzfeldt-Jakob (eyaziwa ngokuthi i-CROYZ-yazizwa i-YAH-cob) isifo esiyingqayizivele se-neurodegenerative yobuchopho esithinta umuntu oyedwa kwisigidi. Ngenye yezinhlobo eziningana zezifo ze-prion.

I-CJD ingabuye ibhekiswe ngokuthi i-spongiform encephalopathy, i-vCJD, kanye no-Jacob-Creutzfeldt.

Ukuvama

I-United States inamacala angama-200 kuya kwangu-300 ngonyaka.

Isilinganiso seminyaka yokuqala siyiminyaka engu-60 ubudala.

Izimpawu ze-CJD

Izimpawu zakuqala kakhulu zihlanganisa ukuhoxiswa-okufana nokuhoxiswa, ukushintsha kwemizwelo nokuntuleka kwesithakazelo kubantu noma ngezimo. Ngokushesha, ezinye izimpawu zakha, kufaka phakathi izinkinga zememori , izinguquko ekuziphatheni, ukusebenzisana okungalungile, ukuhamba okungahleli kahle nokuhamba kahle.

Njengoba lesi sifo siqhubeka sithuthuka, abantu abane-CJD bangase babe nama- hallucinations , psychosis, ukuwohloka kokusebenzisana, ukunyakaza okungenakuzithandela, izingalo ezinzima kakhulu nemilenze, ikhono elibi lokugwinya nokukhuluma, nokukhubazeka kwengqondo. Ekugcineni, lo muntu angase angene e-coma.

Izigaba ze-CJD

• Kancane kancane
  I-CJD ephazamisayo i-85% yazo zonke izifo zesifo. Kancane kancane kusho ukuthi ayikho imbangela ecacile.

• Hereditary
  Ngokusho kweNational Institute of Neurological Disorders and Stroke, amacala azuzwe njengefa alinganiselwa ku-5% kuya kwangu-10%. I-prion protein gene igcina ingajwayelekile kubantu abanezinhlobo zonke ze-CJD. Ezigulini ezinefomu lomndeni, izinguquko zitholakala ku-prion protein gene ezidala amaprotheni okungavamile. Laba bantu ngokuvamile babonisa umlando womndeni wezifo ze-prion.

• Kutholakale
  Kunezinhlobo ezintathu ze-CJD etholakalayo. Lokhu kufaka:

1. Iatrogenic
   Lokhu kubhekisela ku-CJD enqunywe ngenqubo yezokwelapha, njengezinsimbi ezingaqinisekisiwe noma ukuguquka kwezicubu.
2. I-Kuru
   I-CJD ingatholwa ngokusebenzisa ubusika, okubizwa ngokuthi yi-Kuru. Lokhu kubuyele emuva kuma-1950, lapho abantu besizwe sangaphambili ePapua, eNew Guinea bakha amacala amaningi e-CJD ngoba imikhuba yabo yomngcwabo yayihlanganisa abesifazane nabantwana abadla ubuchopho bomuntu oshonile. Njengoba lo mkhuba usuphelile, amacala e-CJD anciphile, kodwa lokhu kuthathe iminyaka eminingana ngoba isikhathi sokukhushulwa kwe-CJD kubonakala sengathi siyiminyaka engama-40.

1. Okuhlukile
   Ukucatshangwa kwe-CJD kucatshangwa ukuthi kubangelwa ukudla inyama enesifo futhi kungase kwenzeke kubantu abasha, abaneminyaka yobudala obuqalayo eyenzeka ngo-28. Lokhu kuvame ukubizwa ngokungafanele ngokuthi isifo sezinkomo ezimbi noma isifo sezinyosi ze-spongiform encephalopathy. Isifo sezinkomo samadodakazi sitholakala kuphela ezinkomeni; uma idluliselwa kubantu, ibizwa ngokuthi i-CJD ehlukile. Lolu hlobo lwe-CJD aluvamile kakhulu; amacala amathathu kuphela aqoshiwe e-United States, nalabo ababili kulabo ababekade bevela ezweni.

Ukubona i-CJD

Njengazinye izifo eziningana zezinzwa, akukho ukuhlolwa okulula ukuhlola i-CJD. Umgomo wokuqala wodokotela ukulawula ezinye izimo ezingase zibe imbangela yokuwohloka komqondo, ikakhulukazi ngoba ezinye izimbangela zokudemeka kwengqondo ziguquguquka, njengokucindezela okuvamile kwe-hydrocephalus ne- vitamin B12 .

Izivivinyo ezifana nephepheni lomgogodla , i- EEG , i- CT , ne-MRI ingasetshenziselwa ukunquma ukuthi kungenzeka kanjani i-CJD.

Ukuqinisekisa ukuxilongwa, odokotela abahlinzayo bangenza i-biopsy ngokususa ingxenye encane yobuchopho ukuhlola. Enye indlela yokwenza i-autopsy ngemva kokufa. Nge-biopsy kanye ne-autopsy, kunengozi yokuthi udokotela ohlinzayo aphethwe yi-CJD lapho ephethe izicubu zobuchopho. Ku-CJD ehlukile, kuye kwaba khona amacala aqinisekisiwe ngemuva kokususwa nokuhlolwa kwamathani amuntu.

Ngakho-ke kubaluleke kakhulu ukuthi izinyathelo zokuqapha kufanele zithathwe ngesikhathi senqubo.

I-CJD ihluke kanjani kune-Alzheimer's?

Ukuqhubeka kwe-CJD kungasheshi kakhulu kunesifo se-Alzheimer's . Abantu abane-CJD bavame ukufa phakathi kwamasonto ambalwa unyaka owodwa. E-Alzheimer's, ngokuvamile kuhla kancane kancane phakathi nenkambo yeminyaka eminingana.

Ukwelashwa kwe-CJD

Okwamanje, akukho ukwelashwa kwe-CJD, nakuba ezinye zezimpawu zinganqunywa imithi. Umgomo ukuhlinzeka induduzo nokukhululeka. Ucwaningo luqhubeka olwenziwe ekuboneni izimbangela kanye nemithi engenzeka yokuphatha i-CJD.

_Imithombo:

_{ADAM Creutzfeldt-Jakob Izifo.Ufinyelele ngo-February 10, 2012. http://adam.about.net/encyclopedia/infectiousdiseases/Creutzfeldt-Jakob-disease.htm}

_{I-Alzheimer's Association. I-Creutzfeldt-Jakob Izifo. Kufinyelelwe ngo-Februwari 10, 2012. http://www.alz.org/alzheimers_disease_creutzfeldt_Jakob_disease.asp}

_{I-Creutzfeldt-Jakob Disease Foundation, Inc. I-CJD Fact Sheets. Kufinyelelwe ngo-Februwari 10, 2012. http://www.cjdfoundation.org/fact.html}

_{I-Creutzfeldt-Jakob Disease Foundation, Inc. I-Creutzfeldt-Jakob Izifo nezinye izifo ze-Prion. Kufinyelelwe ngo-Februwari 10, 2012. http://www.cjdfoundation.org/pamphlets.html}

_{I-World Health Organization. Isifo se-Creutzfeldt-Jakob. Kufinyelelwe ngo-Februwari 10, 2012. http://www.who.int/topics/creutzfeldtjakob_syndrome/en/}