Ama-antihistamine yimithi yomlomo evame ukusetshenziselwa ukuphatha izimpawu ze- rhinitis ye-allergen ne- conjunctivitis ye-allergenic . Basebenza ngokuvimbela izenzo ze-histamine, ikhemikhali ekhishwe ngamaseli omzimba wakho. Imizimba yethu idinga i-histamine. Uma uhlangana ne-allergen, i-histamine isisiza umzimba wakho ukuwuqeda. Kodwa ngezinye izikhathi imizimba yethu ikhiqiza i-histamine kakhulu ekuphenduleni i-allergen engenabungozi, njenge-pollen, ikushiya ngekhala eligijimayo nelanga elimnandi.
Yilapho ama-antihistamine angasiza khona. Ama-Antihistamine ahle kakhulu ekunakekeleni izimpawu zokungezwani komzimba ezifana nokuthungela, izinyosi, nezinyosi, amehlo enamehlo. Nakuba ama-antihistamine abhekwa njengemithi ephephile kakhulu, angakwazi ukuza nemiphumela emibi, kufaka phakathi ukutholakala kwesisindo.
Ubufakazi Bokuba Antihistamines Yenza Ukulinganisa Ukutholakala
Ama-antihistamine amadala, afana ne- Benadryl (diphenhydramine) , abe nemiphumela emibi eyaziwa njengobuthongo, umlomo owomile nokugcinwa komchamo. Nakuba abanye, njengo-Allegra (fexofenadine), bavame ukuba nemiphumela emibi kakhulu. Ucwaningo olushicilelwe encwadini ethi Ukukhuluphala kwathola inhlangano phakathi kokusetshenziswa kwama-antihistamine nokukhuluphala. Kulaba bantu abangaba ngu-900 abafundela, labo abathwala ama-antihistamine-njengeZyrtec no-Allegra-babengase babe namandla ngokweqile noma bangaphezu kwalabo abangathathi ama-antihistamine. Izizathu zalokhu zazingacacile, futhi kubalulekile ukuqaphela ukuthi le nhlangano ayisho ukuthi ama-antihistamine ngokuqondile abangela ukuzuza kwesisindo.
Abacwaningi bathi i-antihistamines inesakhiwo esifanayo samakhemikhali kwezinye izidakamizwa zengqondo ezaziwa ukuthi zihambisana nokuzuza kwesisindo. Ama-antihistamine angase akhulise ukudla, okungaholela ekuzuzeni isisindo.
Abafundi abaningi beli sayithi abaye basebenzisa i-Xyzal (levocetirizine), i-antihistamine efana ne-Zyrtec (cetirizine), bathi baqaphele ukuthi amaphesenti amancane kakhulu eziguli abasebenzisa lesi sidakamizwa ngesikhathi sokuvivinyeka-amakhilogremu engeziwe.
Ama-antihistamine amadala, afana ne-Periactin (cyproheptadine), empeleni asetshenziselwe ukukhula kwesidlo nesisindo sokunciphisa izingane ezingaphansi kwamandla omzimba kanye neziguli zomdlavuza eziphethwe yi-chemotherapy.
Kungani Ama-Antihistamine Asusa Ukulinganisa Isisindo?
Uma ama-antihistamine enza ukuba ulale, amazinga akho wehle we-energy angase aholele ekuzivocavoca umzimba kancane nokuzuza okungaphezulu kwesisindo. Ngaphandle kwalokho, ukukhuluphala kubhekwa njengesimo sokuvuvukala okwenza umuntu angenelele ezinkingeni ezinjengezifo zomzimba. Ngakho-ke ama-antihistamines asetshenziswayo amane nje abe uphawu lomzimba, hhayi imbangela yesisindo somzimba.
Ngombono wami, kungenzeka ukuthi kukhona ukuhlangana phakathi kokusetshenziswa kwama-antihistamine athile nokuzuza kwesisindo. Lokhu kungenzeka nje kuphela umphumela wecala wale mithi engathinta umuntu oyedwa kunomunye. Esinye isibonelo sokuthi akukho into enjengokulingana komzimba owodwa-wonke ukwelashwa kokwelashwa kwemithi. Uma uthatha ama-antihistamine futhi ukhathazekile ngesisindo somzimba, khuluma ne-allergenist noma udokotela wakho.
> Imithombo:
> Couluris M, Mayer J, Freyer D, Sandler E, Xu P, Krischer J. Umphumela we-cyproheptadine hydrochloride (i-Periactin®) ne-megestrol acetate (Megace®) ngesisindo kubantwana abane-cachexia ehlobene nomdlavuza / ukwelashwa. J Pediatr Hematol Oncol. 2008 > November; > 30 (11): 791-797.
> I-Ratliff J, i-Barber J, i-Palmese L, i-Reutenauer E, i-Tek C. I-Association of Prescription H1 Anti-anti-medinines Sebenzisa Ngokukhuluphala: Imiphumela Evela ku-National Health and Nutrition Examination Survey. Ukukhuluphala. 2010; epub 8/12/10.