Nini ukumisa i-Ari Ari, i-Namenda & Excelon ku-Alzheimer's
Isithombe lokhu; Ungumnakekeli oyinhloko womthandekayo wakho, futhi ufuna ukunikeza ukunakekelwa okungcono kunakho konke. Lokhu kuhlanganisa ukucubungula ukuthi imiphi imithi ayitholayo nokuthi ngabe kufanele iqhubeke yini. Yiqiniso, lezi zincumo zenziwa ngokubambisana nodokotela wakhe, kodwa ngemuva kokuba udokotela enikeze isinqumo ngezincomo zabo, cishe uzokucela ukuthi uthole umbono wakho.
Ngakho-ke, yini okufanele uyenze?
Izinzuzo Imithi
Imithi inqunyelwe abantu abane- dementia nethemba lokunciphisa ukuqhubekela phambili noma ngisho nokuthuthukisa ukusebenza kwengqondo isikhathi. Ucwaningo lubonise ukuthi kunenzuzo ethile kule mithi, nakuba ingelapheki lesi sifo.
Ukwelapha Izifo Zama-Alzheimer
Kunezinhlobo ezimbili zemithi enqunyelwe ukuphatha isifo se-Alzheimer's.
- I-Aricept (donepezil): Kuvunyelwe ukuba ibe ne-Alzheimer emnene, elinganisiwe futhi enamandla
- I-Exelon (rivastigmine): Yavunyelwe ukuba i-Alzheimer ibe mncane ukulinganisa
- I-Razadyne (galantamine): Kuvunyelwe ukuba i-Alzheimer ibe mncane ukulinganisa
I-N-Methyl D-Aspartate (NMDA) I-Antagonists
I-Namenda (i-memantine) yinye imithi esetshenziselwa ukunciphisa ukuqhubeka komqondo we-dementia futhi ivunyelwe ukusetshenziswa ngokulinganayo kwesifo esibi kakhulu se-Alzheimer's.
Ukuyeka Imithi
Cabanga ukuyeka imishanguzo uma kuphakama eyodwa noma zombili izici ezimbili ezilandelayo:
Okuqhamuka uma udla imishanguzo
Uma kunemiphumela emibi kakhulu noma ukunciphisa ikhwalithi yokuphila komuntu, kufanele kucatshangelwe ngokuqinile ukuyeka imithi.
Ayikho Inzuzo
Uma isiguli noma othandekayo belokhu ekhona imithi isikhathi esithile futhi manje ukugula kwakhe komqondo kuye kwaqhubekela phambili kuze kube sekupheleni, odokotela kanye nabasokhemisi ngezinye izikhathi bayakuncoma ukuyeka imithi uma kungekho nzuzo ebonakalayo.
Lesi sinqumo kungenzeka, ngezinye izikhathi, senziwe lapho umuntu ekhetha ukunakekelwa kwabahlengikazi , kodwa ngezinye izikhathi kubhekwa njengokukhethwa nje kuphela uma inzuzo ebhekwayo encane noma engekho.
Imithi Kufanele Inqatshelwe Kanjani?
- Yeka imithi kancane kancane
- Yeka imithi eyodwa ngesikhathi
Uma ushiya imithi, qapha othandekayo wakho noma isiguli eduze. Uma uqala ukubona ukwehla okukhulu ekuqondeni noma ekuziphatheni, ungase ufune ukucela udokotela ukuthi aqale kabusha imithi.
Uma ukwehla okuphawulekayo ekusebenzeni kuqhubeka emva kokuyeka, ukuqala kabusha imithi ngokushesha kunokuba kungase kwandise amathuba okuba umuntu abuyele eduze nesikhathi sakhe sangaphambilini (ngaphambi kokuyeka izinga lemithi) yokusebenza.
Ucwaningo Lubonisani?
Akuzange kube nokucwaninga okuningi okwenziwe ekumiseni imithi yokwelashwa komqondo. Kodwa-ke, ucwaningo oluthile lubonakala lubonisa ukuthi abantu abanemithi yokudemeka kwengqondo ekhishiwe banqatshelwe ekuqondeni nasekuziphatheni ngokushesha.
Ucwaningo olulodwa lwaqhathanisa abahlali basekhaya labahlengikazi abanesifo sengqondo sokudemuka komzimba ababehola imithi yokuvimbela ukulimala komzimba ukuze baphathe abanye abantu abahlala ekhaya abahlengikazi abavimbela i-cholinesterase inhibitors.
Abacwaningi bathola ukuthi labo abayekezwa imishanguzo bahlangabezana nezinselelo eziningi zokuziphatha ezifana nokubuzwa okuphindaphindiwe nokukhathazeka kwezempilo njalo. Leli qembu futhi lahlanganyela kancane emisebenzini uma kuqhathaniswa nalabo abasengemithi yabo.
Yenza Isinqumo Esifundo
Esifundweni sami sempilo, ngiye ngabona uhla lwemiphumela emva kokuba imithi yokudemeka kwengqondo isuliwe. Ngezinye izikhathi, kuye kwaba nokuncipha kokusebenza njengoba kuchazwe ngenhla ngemuva kokuyeka imithi; Kodwa-ke, kuye kwaba nezinye izimo lapho kwakukhona ushintsho oluncane kakhulu, uma likhona, emva kokuba imithi yokwehla kwesifo sengqondo iphelile.
Isihluthulelo singamalungu omndeni ukuthi kufanele aqaphele ukuthi kungenzeka ukuthi ukwehla kukhona futhi ukwenza lesi sinqumo kanye nodokotela wabo othandekayo.
Izwi kusuka
Omunye udokotela uhlongoze lo mbuzo olandelayo lapho ecabangela ukuthi noma angayeki yini imithi yokwelashwa kwesifo se-Alzheimer:
"Kukhona yini okuqhubekayo kulokhu kuphila okuhle futhi kungase kungabikho uma imithi imisiwe?" (UDkt. Gene Lammers)
Isinqumo sokuqhubeka noma sokuyeka imishanguzo yesifo se-Alzheimer kufanele sibe esinye esisekelwe ekuthandweni nasekusebenzeni komuntu ngamunye. Mhlawumbe ucabangela umbuzo ongenhla uzosiza ukucacisa izinyathelo zakho ezilandelayo njengoba ufuna okuthandayo.
Imithombo:
I-American Family Physician. 2011 Jun 15; 83 (12): 1403-1412. Ukwelashwa kwezifo ze-Alzheimer. http://www.aafp.org/afp/2011/0615/p1403.html
I-American Journal ye-Geriatric Pharmacotherapy. 2009; 7 (2): 74-83. Umphumela wokwehlisa ukwelashwa kwe-inhibitor ekwenzeni i-cholinterase impawu ekuziphatheni nasekuziphatheni kwamakhasimende asekhaya abahlengikazi abane-dementia. http://www.ncbi.nlm.nih.gov/pubmed/19447360
I-BC Medical Journal, Umq. 53, No. 8, Okthoba 2011, ikhasi (s) 404-408. I-cholineterase inhibitors. http://www.bcmj.org/articles/cholinesterase-inhibitorsphealey_stop_medication_2007-0314.ppt - IDND
UHealey, P. Mashi 14, 2007. Ingabe kukhona isikhathi sokuyeka imithi ethize ye-dementia? phealey_stop_medication_2007-0314.ppt - IDND
Ukuphathwa kwezifo ze-Neurodegenerative. 1.3 (Juni 2011): p191. Buza ochwepheshe: Uvimbela nini i-inhibitor ye-cholinterase ngesifo se-Alzheimer? http://www.futuremedicine.com/doi/abs/10.2217/nmt.11.30
I-New England Journal of Medicine. 2012; 366: 893-903. I-Donepezil ne-Memantine yezifo ezi-Moderate-to-Great Alzheimer's. http://www.iranneurology.com/component/content/article/224-donepezil-and-memantine-for-moderate-to-severe-alzheimers-disease.html
Isikhungo Sokusiza Imfundo Yokuphela / Yokuphila. Imithi Ye-Dementia ekunakekelweni kwe-Palliative. Kufinyelelwe ngo-Februwari 16, 2014. http://www.eperc.mcw.edu/EPERC/FastFactsIndex/ff_174.htm