Ukunciphisa ama-cholesterol akho namazinga e-triglyceride akuyona nje okuhle ukunciphisa ingozi yesifo senhliziyo, kungase futhi kusize ukunciphisa amazinga akho aphakanyisiwe e-PSA. I-PSA, i-antigen ethi i-antigen, i-marker evame ukusetshenziselwa ukulinganisa impilo ye-prostate emadodeni - futhi ingasetshenziselwa ukunquma ukuthi kungenzeka yini khona umdlavuza wesifo sofuba noma ezinye izimo zezokwelapha ezibandakanya i-prostate.
Ukuphakama kwamazinga e-PSA akho, kuphakama ingozi yakho yokuba nomdlavuza wesicathulo noma i-prostate ekhulisiwe. Nakuba kunezimo lapho amazinga e-PSA angase abe nomdlavuza ophezulu futhi awukatholakali, kungcono kakhulu ukuba namazinga e-PSA aphansi ngangokunokwenzeka. Kunezifundo ezimbalwa ezivele ziphakamisa ukuthi kungase kube nobuhlobo phakathi kwamazinga akho e-cholesterol namazinga akho e-PSA.
Ubudlelwano Phakathi kweCholesterol ne-PSA Levels
Ucwaningo oluthile lwamadoda oluthola ukuthi, ngemva kokuqala ukwelashwa kwesimiso sokunciphisa amazinga e- LDL ama- cholesterol, amazinga e-PSA ancipha phakathi kuka-4 no-40%. Ucwaningo olulodwa lucacise ukuthi kuzo zonke izintathu ezingaphansi kwe-10% ezinciphisa i-cholesterol ezenziwe yiziqu, amazinga e-PSA ahlaselwa cishe ngo-1.6 ng / mL. Lobuhlobo bubonakala bubonakala kakhulu kubantu abamhlophe, kodwa hhayi amadoda amnyama. Emadodeni amhlophe, ukwanda kwe-serum prostate serum antigen kuhlotshaniswa namazinga amaningi we-cholesterol namazinga e-LDL ama-cholesterol.
Kodwa-ke, izifundo azange zenze ubuhlobo phakathi kwe-PSA ne-HDL ye-cholesterol noma amazinga we-triglyceride.
Ungakwazi Ukunciphisa Izinga Lakho Le-Cholesterol Futhi Nciphise Amazinga A-PSA?
Kusukela manje, abukho ubufakazi obanele bokuseka ubuhlobo obucacile noma incazelo phakathi kwamazinga e-PSA aphakanyisiwe namazinga aphezulu e-cholesterol.
Nakuba kubonakala sengathi ukunciphisa amazinga aphezulu e-cholesterol kunganciphisa amazinga e-PSA, okwamanje aziwa ukuthi yiluphi uhlobo lomphumela lokhu okungaba nalo engozini yomdlavuza wesifo sofuba noma isifo. Ukwengeza, aziwa ukuthi ukwehlisa amazinga akho e-lipid kunciphisa ingozi yokuba neyodwa yalezi zimo zempilo - noma uma lesi sifo sikhona naphezu kwezinga le-PSA elingaphansi nge-cholesterol-ukwehlisa ukwelashwa.
Ucwaningo oluhlolisisa ubudlelwane phakathi kwe-cholesterol ne-PSA lusetshenziselwa ukubeka phansi ama-cholesterol amazinga. Ngakho-ke, kungase kungabi ubuhlobo phakathi kwe-cholesterol ne-PSA efuna ukuphenywa okuqhubekayo - kodwa ukusetshenziswa kwezimpawu zesimo se-prostate. Izitembu zinezici ezihlukile - ngaphandle kokunciphisa lipids - okubandakanya ukwehlisa ukuvuvukala. Kuze kube yilapho kuqhutshelwa izifundo ezengeziwe, aziwa ngokucacile uma amazinga ephakeme we-cholesterol ahambisana namazinga aphezulu e-PSA nokuthi lokho ubuhlobo bungasho ukuthini.
Umthombo:
UHamilton RJ, Platz EA, Goldberg KC, Freedland SJ. Ubuhlobo phakathi kwe-cholesterol ne-PSA. J Urol 2008; 179: 721 abstract 2094.
Zapata D, Howard LE, Allott EH et al. Ingabe i-PSA ihlobene ne-serum cholesterol futhi ingabe ubuhlobo buhlukile phakathi kwabantu abamnyama nabamhlophe? I-Prostate 2015; 75: 1877-1885.
YuPeng L, YuXue Z, PengFei L, eta l. Amazinga e-cholesterol egazini kanye nengozi yomdlavuza wesi-prostate: ukuhlaziywa kwe-meta-ukuhlaziywa kwezifundo ezingu-14. I-Cancer Epidemiol Biomarkers Ngaphambi kuka-2015; 24: 1086-1093.
Hamilton RJ, Goldberg KC, Platz EA, et al. Ithonya lemithi ye-statin kumazinga e-antigen aqondene ne-prostate. J Natl Cancer Inst 2008; 100: 1511-1518.