Hamba ngezinsizakalo zekhemisi yangakini, futhi uzobona izinhlobo eziningi zokulwa nama-antibiotics ngendlela yama-creams, ama-salves namafutha (cabanga ngo- Neosporin ne-Polysporin). Kodwa-ke, ngenxa yokuthi ungathenga ngokukhululekile le mikhiqizo futhi uyisebenzise isikhangiso se-libitum asisho ukuthi isebenza kahle. Ngaphezu kwalokho, ukusetshenziswa okungalungile kwama-antibiotic angokwemvelo kungabangela ingozi yempilo yomphakathi ngendlela yokwanda kwama-antibiotic .
Ngokuvamile, ama-antibiotiki angama-topical ayencane kakhulu (okusekelwe ebufakazini) asebenzisa.
I-acne
Uma isetshenziselwa ukwelapha izinyosi, ama-antibiotic aphezulu angasetshenziselwa ukwelashwa kuphela (monotherapy) izinyanga ezingaphezu kwezintathu.
I-acne elula yokulinganisela ingaphathwa ngama-antibiotic asobuciko afana ne-clindamycin, i-erythromycin, ne-tetracycline ngaphezu kwe-benzoyl peroxide. Uma lisetshenziselwa inhlanganisela. i-benzoyl peroxide kanye nama-antibiotic e-antibiotic anciphisa ingozi yokuthi izinkinga eziphikisanayo ze- Propionibacterium acnes (P. acnes) zizovela. Okuphawulayo, uP. acnes yi-bacteria ekhula kancane, e-gram-positive efaka isandla ekuthuthukiseni induna.
I-Clindamycin cishe iphumelela kakhulu kune-erythromycin lapho ilapha izidakamizwa isikhathi eside. Ngaphezu kwalokho, i-clindamycin iye yahlanganiswa nokuncipha kwinani lamnyama (ama-comedones kanye nama-microcomedones) afana ne-acne. Ngaphezu kokuhlanganiswa ne-benzoyl peroxide, i-clindamycin ingabuye ihlanganiswe ne-tretinoin yokwelashwa kwama-acne.
Enye i-antibiotic engokwemvelo engasetshenziselwa ukwelapha izinyosi noma yedwa noma ehambisana nezinye izidakamizwa i-dapsone. Ngokuthakazelisayo, i-dapsone yayisetshenziselwa ukuphatha abantu abanesifo sochoko lapho odokotela beqaphela ukuthi futhi kuncishiswe ukuncipha. Ngokungafani ne-dapsone yomlomo engabangela i-héemolytic anemia ebulalayo kubantu abanokuntuleka kwe-G6PD; Kodwa-ke, i-dapsone yama-topical iphephile ngoba ayixhunyiwe egazini.
Encwadini ehlobene nayo, uma isetshenziselwa ukwelapha izinyosi, ezinye izibulala-mpilo ezingamane nje zilwa nokutheleleka kwebhaktheriya kodwa futhi zinciphisa ukuvuvukala.
Amanxeba
Ngama-1960 kanye no-1970, odokotela bathola ukuthi ukusetshenziswa kwama-antibiotics ezihlotsheni zezokwelapha kumahlumela okuhlinzeka ngokuphawulekayo kwehlisa ingozi yokutheleleka. Ngaphezu kwalokho, indawo enomanzi eyingxenye esungulwe ngokusetshenziswa kwama-antibiotic okukhuthaza ukuphulukiswa. Muva nje, ubufakazi obuncane bubonisa ukuthi ama-antibiotic angama-topical avimbela ukutheleleka emaqenjini. Noma kunjalo, ama-pharmacy amaningi asayithengisa ama-antibiotic esiphezulu ngesithembiso sokuthi asiza ukulwa nokutheleleka.
Okungenani izizathu ezimbili, ukusetshenziswa kwama-antibiotics angamaqanda kungaphephile. Okokuqala, ama-antibiotiki angamahlaya kanye namanye ama-antibiotic asetshenziselwa ukunakekelwa kwezilonda kubangele ukuvela kwama-antibiotic-resistant bacteria, ikakhulukazi i- MRSA . Okwesibili, abantu bavame ukuhlaselwa yizifo ezithathelwanayo emithonjeni ye-antibiotics njenge-neomycin ne-bacitracin. Lezi zindlela ezithathelwanayo zibonakala njenge-dermatitis noma isikhumba sokuvuvukala futhi zingahlushwa yi-application eqhubekayo yama-antibiotic, okuvame ukwenzeka ngokunakekelwa kwesilonda.
Isinqumo sokuthi kufanele usebenzise ama-antibiotics wamakhondomu ekunakekelweni kwezilonda kufanele sishiye kudokotela wakho. Ekugcineni, ama-antibiotiki angama-topiki angasiza kuphela i-subset encane yeziguli ezinamanxeba afana nalabo abangakwazi ukuzivikela noma abanesifo sikashukela.
Ngaphezu kwalokho, ngezinhlungu ezincane zokuhlinza-izilonda ezidalwe ngesikhathi senqubo ye-aseptic efana ne-biopsy-anti-antibiotics yesikhumba cishe ayinayo.
Impetigo
I-Impetigo yikhumba evamile noma ukutheleleka kwezicubu ezithambile ngokuvamile ezibangelwa amagciwane e-staph noma strep. Ngomnyaka we-1980 nango-1990, i-mupirocin ye-antibiotic ye-topical yayibhekwa kangcono kune-neomycin noma i-polymyxin ekwelapheni impetigo. Namuhla, ngenxa yokuphakama kwe- MRSA nezinye izinhlobo zama-antibiotic-resistant bacteria, i-mupirocin ayikwazi ukusebenza ezimweni eziningi ze-impetigo. Eqinisweni, uma unesifo socansi noma isicathulo esincane, udokotela wakho cishe uzokunikeza antibiotic ngomlomo njengoKeflex noma i-Trimethoprim-Sulfamethoxazole (TMP-SMX) esebenzayo ne-MRSA.
Ekuphetheni, ama-antibiotiki asemihlolweni anezokwelapha kakhulu. Okungcono kakhulu, uma uthenga ama-antibiotic e-topical ukuze uzenzele ukwelapha, cishe uchitha imali yakho. Okubi nakakhulu, ubamba iqhaza ekuphikiseni ama-antibiotic kanye nesikhumba sokungabi naso.
Imithombo:
Bhatia A, Maisonneuve JF, Persing DH. I-PROPIONIBACTERIUM I-ACNES NEZINHLOKO ZEZIKHONI. Ku: Forum of Medicine (US) Forum on Microbial izinsongo; I-Knobler SL, i-O'Connor S, i-Lemon SM, ne-al., Abahleli. I-Etiology Ephathelene Nezifo Ezigulayo: Ukuchaza Ubuhlobo, Ukwandisa Ucwaningo, Nokunciphisa Imiphumela: Isifinyezo Semisebenzi. Washington (DC): National Academy Press (US); 2004. Itholakala kusuka: http://www.ncbi.nlm.nih.gov/books/NBK83685/
Isihloko esibizwa ngokuthi "Ukuvuselela emithonjeni yokulwa namagciwane e-dermatology" yi-CR Drucker eyanyatheliswa ku-Dermatologic Therapy ngo-2012.