Kuyini, ukuthi isetshenziswa kanjani
Ukuskena kwe-MUGA (ukuskena kwe-MUltiple Gated Acquisition) kuyisivivinyo esingavumelekile esetshenziselwa ukuhlola ukusebenza komzimba. Iskena se-MUGA sikhiqiza isithombe esithinta inhliziyo senhliziyo yokushaya, futhi kusukela kulo mfanekiso izici eziningana ezibalulekile zinganqunywa ngempilo yama-ventricle angakwesokunxele nangakwesokudla (amakamelo amakhulu okupompa inhliziyo). I-scan ye-MUGA inhle kakhulu ekunikezeni ukufundwa kwekhono lokuphambuka kwenhliziyo.
I-MUGA ikwenziwe kanjani?
Uma unesisindo se-MUGA, inani elincane le-Technetium 99 (i-substanceactive radio) lijojelwe egazini lakho. I-Technetium 99 ihlanganisa amangqamuzana akho abomvu egazi, futhi ijikeleza ngaphakathi kwegazi lakho. Uzobekwa ngaphansi kwekhamera ekhethekile (ikhamera ye-gamma), ekwazi ukuthola imisebe ephansi ekhishwa ngamaseli abomvu abhalwe nge-Technetium. Ngenxa yokuthi amangqamuzana egazi abomvu agcwalisa amakamelo enhliziyo, ikhamera ye-gamma iyakwazi ukukhiqiza ukuthi yikuphi ngempela i-movie yenhliziyo yokushaya. Le "movie" yedijithali ingahlaziywa nge-algorithms ehlukahlukene yekhompyutheni, enganquma ulwazi oluningi oluwusizo mayelana nempilo yonke yenhliziyo yakho.
Yini Engayifunda Ku-MUGA Scan?
Izici eziningana ezibalulekile zomsebenzi wenhliziyo zingalinganiswa kusuka kuskena se-MUGA. Uma umuntu enesifo senhliziyo isisindo se-MUGA singatshela ukuthi iyiphi ingxenye yesisu senhliziyo esebenza ngokungavamile.
Ngokuthola indawo yokulimala kwemisipha yenhliziyo, iskena se-MUGA sinikeza udokotela izincazelo ezibalulekile mayelana nokuthi yiziphi izifo zomzimba ezivame ukuvinjelwa noma ukuvinjelwa kancane ngenxa yokushaya isifo sofuba .
Ukuskena kwe-MUGA nakho kuhle kakhulu ekulingeni umsebenzi jikelele wenhliziyo. Lokhu kubaluleke kakhulu uma kukhona i-degree of cardiomyopathy etholakalayo .
iskena se-MUGA sinikeza izindlela ezinembile zokukhiqiza nokuqapha "ingxenyana ye-ejection" ye-ventricles yenhliziyo. Ingxenyana ye-ejection ye-ventricular ejection (LVEF) iyisilinganiso esihle kakhulu sokusebenza kwenhliziyo yonke, futhi iyasiza kakhulu ekusizeni odokotela ukuhlola nokuphatha abantu abanesifo senhliziyo .
Ngabe i-MUGA ihlola okuningi kunenzuzo kunezinye izinkinga zezinhliziyo?
Kunezinzuzo ezimbili ezijwayelekile ze-MUGA ukuskena phezu kwamanye amasu (njenge- echocardiogram ) yokuhlola ukusebenza komzimba.
Okokuqala, i-LVEF etholakala nge-scan ye-MUGA inembile kakhulu, futhi ibhekwa njengenembile kakhulu kunezingqinamba ze-LVEF ezitholwe ezinye izinhlobo zokuhlolwa kwenhliziyo.
Okwesibili, i-LVEF eyalinganiswa nengxenyana ye-EUGection ye-MUGA isakhiwe kakhulu. Lokhu kusho ukuthi uma i-MUGA esilandelayo ihlola umehluko ku-LVEF, lokohluko kungenzeka ukuthi ubonakalise ukuguqulwa kwangempela esimweni senhliziyo (futhi akuyona isakhi sokulinganisa okungalungile). Ngezinye izivivinyo, ukuhlukahluka kokulinganisa okuphindaphindiwe kwe-LVEF kuvame ukuba mkhulu.
Lezi zici ezimbili zenza ukuskena kwe-MUGA kubaluleke kakhulu ekutholeni izinguquko ezicashile emsebenzini womuntu womuntu ngokuhamba kwesikhathi.
Isibonelo esivamile sokuphindaphindiwe kokuhlolwa kwe-MUGA kuyasiza ekuhloleni umsebenzi wezinhliziyo zomuntu phakathi nenkambo ye- chemotherapy yomdlavuza.
Amanye ama-chemotherapeutic agents (i- Adriamycin eyona ephawuleka kakhulu) ingaba yinto enobuthi kakhulu emzimbeni wenhliziyo.
Iskena se-MUGA sinembile futhi sinokuphindaphinda ngokwanele ukuthola ukucabangela, izinguquko zakuqala emsebenzini wenhliziyo okungase kungabikho kalula ngamanye amasu. Ngokulinganisa i-LVEF ngezikhathi ezithile ze-MUGA, ama-oncologists anganquma ukuthi kuphephile yini ukuqhubeka ne-chemotherapy, noma ngabe imithi ethile kufanele imiswe.
Ukulinganiselwa kwe-MUGA Scan
Njenganoma yikuphi ukuhlolwa kokuhlola okusetshenziselwa ukwelashwa, kunezinye izithiyo ezingenakubalwa ekusesheni kwe-MUGA.
Ngenxa yokuthi ukuskena kwe-MUGA kudinga ukusetshenziswa komuthi omsakazo, umuntu onesiskena uyadluliselwa emanzini amancane.
Inani lemisebe ehlanganiswa ne-scan ye-MUGA cishe ngo-6.2 mSv, okungaba kabili imisebe engokwemvelo evamile umuntu ayithola ngonyaka owodwa, futhi izikhathi ezingaba ngu-10 imishanguzo etholakalayo ne- mammogram .
Ngaphezu kwalokho, ukunemba kwe-LVEF etholakala nge-scan ye-MUGA kuncipha ukunciphisa iziguli ezinezinhliziyo ezingavamile, ikakhulukazi i- friday friction .
Futhi, ukuskena kwe-MUGA ngokuvamile akunikezi ulwazi oluthe xaxa mayelana nokusebenza kwamagundane enhliziyo, noma ngabe kune -hypertrophy ye-ventricular . I-echocardiogram, ngokuphambene, inhle kakhulu ukuthola ulwazi olunjengale. Ngakho-ke, kubantu abaningi abanezinkinga zenhliziyo ezisolisayo, iskena se-MUGA kumele sisetshenziswe ngokuhambisana nezinye izivivinyo zenhliziyo ukuze zithole isithombe esigcwele ngangokunokwenzeka isimo somuntu jikelele senhliziyo.
> Imithombo:
> Hendel RC, Berman DS, Di Carli MF, et al. I-ACCF / ASNC / ACR / AHA / ASE / SCCT / SCMR / SNM 2009 Imigomo Yokusetshenziswa Efanelekayo Yomfanekiso We-Cardiac Radionuclide: Umbiko We-American College of Cardiology Foundation Imigomo Yokusetshenziswa Efanelekayo, i-American Society of Nuclear Cardiology, i-American College of I-Radiology, i-American Heart Association, i-American Society of Echocardiography, i-Society of Cardiovascular Computed Tomography, i-Society for Cardiovascular Magnetic Resonance, ne-Society of Nuclear Medicine. Ukujikeleza ngo-2009; 119: e561.