Uma uhlala nesimo esifana ne-osteoarthritis noma ukucindezeleka, kungenzeka usuvele wazi ukuthi zingathinta kanjani ezinye izici zempilo yakho, okufaka ezinkingeni ezifana nokuzuza isisindo, ukugula okulukhuni, nobuhlungu obungapheli.
Enye ikhambi esho ukunciphisa ukucindezeleka, i-arthritis, nezinye izimo yi-SAMe eyengeziwe, eyaziwa ngokuthi i-SAM-e, i-ademetionine, noma i-S-adenosylmethionine.
I-SAM iyindlela yokwenziwa komshini okhiqizwa ngokwemvelo emzimbeni kusuka ku-methionine (i-amino acid ebalulekile) ne-adenosine triphosphate (i-compound-producing component).
I-SAM ayitholakali ngokwemvelo ekudleni. Umzimba ngokuvamile wenza lokho okukudingayo impilo enhle, noma kunjalo, ezinye izifo zisho futhi amazinga aphansi okuthiwa i-methionine, i-folate, noma i-vitamin B12 ikholelwa ukuthi ifaka amazinga aphansi e-SAMe.
Kucatshangwa ukuthi i-SAMe ingasiza ekukhuthazeni ukukhiqizwa kwamakhemikhali eyaziwa ukuthi badlale indima ebalulekile ezinhlobonhlobo zezinqubo emzimbeni, njengokulawulwa kwemizwelo, ukusebenza komzimba, nokubona ubuhlungu.
Kungani Abantu Bathatha Ama-SAMe Supplements?
I-SAM isetshenziswa ngokujwayelekile ezindabeni zezempilo ezilandelayo:
- Ukukhathazeka
- Ukucindezeleka
- I-Fibromyalgia
- I-osteoarthritis
- Ubuhlungu
- I-Premenstrual syndrome (PMS)
I-SAMe kuthiwa ikhulisa ukusebenza kwengqondo, ikhulisa impilo yebindi , ikhubaza inqubo yokuguga, futhi isiza abantu ukuba bayeke ukubhema.
Izinzuzo: Ingabe Kungasiza Ngempela?
Nakhu ukubuka ezinye ucwaningo ngezinzuzo ezikhona ze-SAMe.
1) i-osteoarthritis
U-SAM uveza isithembiso ekwelapheni i -osteoarthritis yamadolo noma i-hip. Kuthiwa ukukhulula ubuhlungu futhi kube nezakhiwo eziphikisayo, kanti ucwaningo oluthile lubonisa ukuthi lungakhuthaza u-cartilage ukukhanda.
Ngombiko oshicilelwe kwi- Database Cochrane Yokuhlolwa Okuhlelekile ngo-2009, abacwaningi bahlaziya izilingo ezine zomtholampilo ezishicilelwe ngaphambilini (ezinama-656 abahlanganyeli) futhi bathola ukuthi ukusetshenziswa kwe-SAMe kungasiza ukunciphisa ubuhlungu nokuthuthukisa umsebenzi kubantu abane-osteoarthritis.
Njengoba izivivinyo ezibukeziwe ziyizinga elibi, noma kunjalo, abalobi bokubukeza babheka ukuthi lezi zitholakele azifinyeleli.
2) Ukucindezeleka
Ekuhlaziyweni kocwaningo olwanyatheliswa ku- Cochrane Database yezobuchwepheshe obuhlelekile ngo-2016, ososayensi bahlaziya ukuhlolwa kwemitholampilo eyedlule eyisi-8 ngaphambilini eyaqhathaniswa ne-SAMe kuma-anti-depressants imipramine, desipramine, noma i-escitalopram, noma i-placebo.
I-SAM iphakeme kune-placebo lapho isetshenziselwa i-serotonin reuptake inhibitor (SSRI) ehlukunyezwayo, kodwa ubufakazi bubhekwa njengezinga eliphansi. Uma kuqhathaniswa ne-imipramine, abahlanganyeli abambalwa babhekana nemiphumela emibi uma bephathwa ngefomu lokujova le-SAMe. I-SAM ayengafani ne-placebo noma i-antidepressants efana ne-imipramine noma i-escitalopram uma isetshenziswe yedwa.
Ekuphetheni kwabo, abalobi bokubukeza bathi ukusetshenziswa kwe-SAMe ngokucindezeleka kudinga ukuphenywa ngokuqhubekayo ezinkulingweni ezinkulu nezihlelwe kahle "okunikezwa ukungafi kobufakazi obuphezulu futhi ukungakwazi ukuthola iziphetho eziqinile ngokusekelwe kulobo bufakazi."
3) i-Fibromyalgia
Ekubukezeni kocwaningo olwanyatheliswa ku- Journal of Complementary and Alternative Medicine ngo-2010, ososayensi babheka izivivinyo ezingama-70 ezishicilelwe ngaphambilini ezitholakala ekuhloleni ukusetshenziswa kwezinhlobo ezihlukahlukene zokwelashwa okuhambisanayo kokukhathala okungavamile kwe-syndrome kanye ne-fibromyalgia.
Ngokuhambisana ne-magnesium, i-L-carnitine, ukukhwabanisa, nezinhlobo eziningana zokuziphatha okuzindla, abalobi bokubukeza okuthiwa yi-SAMe phakathi kwezinyango zokwelapha okusemandleni okuqhubeka nokucwaninga ngokusebenza kwabo ngalezi zimo.
4) Isifo Sesibindi
I-SAMe ingathuthukisa ukusebenza kwesibindi kubantu abanesifo esingenasifo sesibindi, siphakamisa ukubuyekezwa kocwaningo okushicilelwe emaphepheni we- PLoS One ngo-2015. Noma kunjalo, ekuhloleni izivivinyo eziyi-12 ezishicilelwe ngaphambilini ezitholakala ekubuyekezeni, abalobi bathole nokuthi i-SAMe ingase ibe nenzuzo encane ekwelapheni izimo ezithile zesibindi njenge-hepatitis ye-viral kanye ne-cholestasis.
Imiphumela Ezingenakwenzeka
I-SAM ingase ibangele imiphumela eminye emibi, kuhlanganise nokukhathazeka, ukuqothulwa, isifo sohudo, umlomo owomile, ukukhwehlela ikhanda, ukushona kwenhliziyo, ukuleleka, igesi, ishukela ephansi yegazi, ukucabangela, ukuphazamiseka, ukukhwabanisa isikhumba nokuhlanza. Inani elikhulu le-SAMe lingabangela i-mania (imizwelo engavamile). Kukhona nokukhathazeka okunye ukuthi ukusetshenziswa kwe-SAMe kungabangela ukusabela okwenziwe kwabanye abantu.
Uma une-bipolar disorder, i-Lesch-Nyhan syndrome, isifo sika-Parkinson, noma ezinye izimo zezempilo, kufanele usebenzise kuphela i-SAMe ngaphansi kokuqondiswa komhlinzeki wakho wezempilo njengoba kungase kube nzima kakhulu izimpawu.
Kubalulekile ukuqaphela ukuthi kungase kube nezingozi uma kuhlanganiswa i-SAMe nemithi noma ezinye izithako. Akufanele uthathe i-SAMe ngokuhambisana nama-antidepressants, imithi yokukhwehlela, imithi yesifo sikashukela, i-levodopa (L-dopa), i-L-tryptophan, imithi ethinta amazinga e-serotonin, i-wort yaseSt. John, noma enye imithi ngaphandle kokuba uhlolwe yimpilo ochwepheshe. I-SAM kumele ihoxiswe okungenani amasonto amabili ngaphambi kokuhlinzwa okuhleliwe.
Ukuphepha kwe-SAMe ezinganeni, abesifazane abakhulelwe noma abahlengikazi, noma abantu abanezinso noma isifo sesibindi ayisungulwa. Ungathola amathiphu ekusebenzisa izithako ngokuphepha , kodwa kufanele ukhulume nomhlinzeki wakho oyinhloko ngaphambi kokuthatha i-SAMe ukuze uxoxe ukuthi ikufanele yini. Khumbula ukuthi i-SAMe akufanele isetshenziswe njengengxenye yokulashwa okujwayelekile.
Izwi elivela
Ukuphila nanoma yisiphi isimo esingapheliyo akulula. Ngenkathi ezinye izifundo zikhomba ukuthi i-SAMe ingase inikeze ezinye izinzuzo, asikwazi ukuqina ngokuxhumeka kuze kube yilapho ihlelwe kahle, ukuhlolwa okukhulu kwemitholampilo (uhlobo locwaningo ongathanda ukulubona ukubeka isamba esigcwele kokwelashwa) .
Kubuye kubalulekile ukukhumbula ukuthi i-SAMe akufanele isetshenziswe ngokuhlanganyela noma endaweni yokwelapha ekhuthazwa udokotela wakho. Uma ucabangela ukuzama ukwesezela i-SAMe, qiniseka ukuthi uxoxe nodokotela wakho ukuze uhlole izinzuzo nezenzalo futhi uxoxe ngokuthi kufanelekile yini.
> Imithombo:
> Galizia I, Oldani L, Macritchie K, et al. I-S-adenosyl Methionine (i-SAMe) yokucindezeleka ku-Adult. I-Cochrane Database Syst Rev. 2016 Okthoba 10; 10: CD011286.
> Guo T, Chang L, Xiao Y, Liu Q. S-adenosyl-L-methionine ye-Treatment of Chronic Chronic Illness: Ukubuyekezwa Okuhlelekile kanye ne-Meta-Analysis. PLoS One. 2015 Mar 16; 10 (3): e0122124.
> Porter NS, Jason LA, Boulton A, Bothne N, Coleman B. Ukungenelela Kwezokwelapha Okunye Okusetshenziselwa Ukwelashwa Nokuphathwa Kwe-Myalgic Encephalomyelitis / Chronic Chronic Fatigue Syndrome kanye neFibromyalgia. J Altern Supplement Med. 2010 Mar; 16 (3): 235-49.
Ukuziphendulela: Ulwazi oluqukethwe kule sayithi luhloswe ngezinjongo zemfundo kuphela futhi aluthathi iseluleko, ukuxilongwa noma ukwelashwa ngudokotela olayisensi. Akuhloselwe ukumboza zonke izinyathelo zokuqapha, ukusebenzisana kwezidakamizwa, izimo noma imiphumela emibi. Kufanele ufune ukunakekelwa okusheshayo kwezokwelapha kunoma yiziphi izinkinga zezempilo bese uthintana nodokotela wakho ngaphambi kokusebenzisa enye imithi noma wenze ushintsho ohlelweni lwakho.