I-Fibromyalgia yisimo esingapheli esibonakala ngokuhlanganiswa kobuhlungu obubanzi emisipha, izintambo, imigudu, ukukhathala, namaphuzu amaningi amathenda emzimbeni. Amaphuzu amathenda ayizindawo eziqondile noma ezibuhlungu lapho kusetshenzwa ingcindezi, ikakhulukazi entanyeni, emahlombe, emhlane wangaphambili, esifubeni esiphezulu, emaceleni, emhlane, ezinqeni nasemathangeni.
Abantu abane-fibromyalgia bangase bahlangane nezinye izimpawu nezimo, njengokulala okungapheliyo , ukugula okungenasifo , isifo esibuhlungu , ukukhathazeka kwe-TMJ , ukukhathazeka, ukucindezeleka , imilenze yezinyawo ezingenalutho , ukungabi namandla noma ukugubha ezandleni nasezinyaweni, ukugxila okuncane, izikhathi zokugaya esikhathini esibuhlungu , futhi ukuzwela okwephunga, imisindo, izibani ezikhanyayo nokuthinta.
Ngokusho kwe-American College of Rheumatology, i-fibromyalgia ithinta abantu abayizigidi ezingu-3 kuya kwezi-6 e-United States. I-Fibromyalgia ivame kakhulu kubantu besifazane, ikakhulukazi phakathi kweminyaka engama-30 no-50.
Amakhemikhali kanye nama-Supplements for Fibromyalgia
Kuze kube manje, ukwesekwa kwezesayensi sokuthi noma yimaphi amakhambi angaphatha i-fibromyalgia ayitholakali.
1) I-S-adenosylmethionine (i-SAMe)
I-S-adenosylmethionine (i-SAMe) iyinhlanganisela eyenzeka ngokwemvelo emzimbeni. Kuyadingeka ukuze kusetshenziswe kahle amasistimu omzimba omzimba, izingqamuzana zamangqamuzana, ama-neurotransmitter afana ne-serotonin, i-norepinephrine, ne-dopamine, i-cartilage ne-DNA.
Izifundo ezimbalwa zokuqala zisho ukuthi i-SAMe ingasiza nge-fibromyalgia. Ucwaningo oluthile oluncane olwenziwe ngokuphindaphindiwe lwaluhlola umphumela we-S-adenosylmethionine (i-SAMe) noma i-placebo kubantu abangu-17 abane-fibromyalgia, abangu-11 kubo ababenenkinga yokucindezeleka. Inani lamaphuzu wethenda linciphile emva kwe-SAMe kodwa hhayi indawo ye-placebo. Ukucindezeleka, njengoba kuhlolwe izilinganiso ezimbili zokulinganisa, kuthuthukisiwe emva kwe-SAMe kodwa hhayi indawo ye-placebo.
Kwesinye isifundo se-double blind, abantu abangu-44 abane-fibromyalgia bathatha u-800 mg we-S-adenosylmethionine ngosuku noma i-placebo. Ngemuva kwamasonto angu-6, kube nokuthuthukiswa okuphawulekayo kwezibalo ebuhlungu, ukukhathala, ukuqina kokusa, imizwa, kanye nomsebenzi wesifo somtholampilo. Isibalo samaphuzu we-tender, amandla omzimba, nesimo sengqondo (okuhlolwe yi-Beck Depression Inventory) akuzange kube ngcono nakakhulu nge-SAMe kune-placebo.
Kodwa-ke, enye inhlolovo ephindwe kabili iqhathanisa uSAMe (600 mg ngosuku) elawulwa ngaphakathi ngaphakathi noma endaweni ye-placebo kubantu abangu-34 abane-fibromyalgia. Ngemuva kwezinsuku ezingu-10, kwakungekho umehluko ophawulekayo kumaphuzu wethenda.
I-SAM ingabangela ukuhlushwa, umlomo omile, nokulala. Ngokuvamile, abantu bathola isifo sohudo esinzima, ukukhwehlela, ukukhwabanisa, nokuthola isizungu.
Abantu abanenkinga yokuguquguquka kwe-bipolar akufanele bathathe i-SAMe, njengoba kungase kube nzima kakhulu iziqephu ze-manic. Abantu abazithatha i-levodopa yezidakamizwa (okuvame ukushiwo isifo sikaParkinson) kufanele bagweme i-SAMe. Abantu abasebenzisa izidakamizwa akufanele basebenzise i-SAM ngaphandle kokubonisana nodokotela wabo kuqala. Ukuphepha kwe-SAMe kwabesifazane abakhulelwe noma abahlengikazi noma abantwana abazange basungulwe.
2) i-magnesium
I-Magnesium iyimithi yamaminerali etholakala ngokwemvelo ekudleni okufana nemifino eluhlaza, amantongomane, imbewu, kanye nezinhlamvu ezigcwele kanye nezithako zokudla okunomsoco.
I-magnesium iyadingeka ekusebenzeni okungaphezu kuka-300 kwemvelo. I-magnesium, kanye ne-malic acid (isithelo se-acid esitholakala ngokwemvelo ema-apula) kuvame ukuphakanyiswa kubantu abane fibromyalgia ngoba bobabili badinga ukukhiqizwa kwamandla amangqamuzana ngendlela ye-adenosine triphosphate (ATP). Kodwa-ke, isifundo esisodwa sabantu abangu-97 asikho ukuhlangana phakathi kwamazinga we-magnesium ne-fibromyalgia.
Ucwaningo oluphindwe kabili luhlolisise ukuphumelela nokuphepha kwe-magnesium (50 mg kathathu ngosuku) kanye ne-malic acid (200 mg kathathu ngosuku) kubantu abangu-24 abane-fibromyalgia. Ngemuva kwamasonto amane, inhlanganisela ye-magnesium / i-malic acid ayiphumelelanga kakhulu kune-placebo.
Ababambiqhaza kamuva bathola izinyanga ezingu-6 zokuhlanganiswa kwamanani amakhulu (kufika ku-300 mg magnesium no-1200 mg we-malic acid ngosuku) izinyanga ezingu-6. Ngalesi sikhathi, inhlanganisela yabangela ukuthuthukiswa okuphawulekayo ebuhlungu nasekuthandeni, kodwa lesi sigaba socwaningo kwakuyilebuli evulekile (bobabili abacwaningi nabahlanganyeli bayazi ukuthi imaphi ukwelashwa kuqondiswa) futhi bangaboni, ngakho-ke imiphumela, ngenkathi ithembisayo, ayikwazi kufanele isetshenziswe njengobufakazi bokuthi inhlanganisela yayiphumelele. Izifundo ezengeziwe ziyadingeka.
Amazinga aphezulu we-magnesium angabangela isifo sohudo, isisindo sokuphefumula, ukulahlekelwa isifiso sokudla, ukubuthakathaka kwemisipha, ukuphefumula kanzima, ukucindezelwa kwegazi okuphansi, izinga lokushaya kwenhliziyo, nokudideka. Ingakwazi ukuxhumana nemithi ethile, njengaleyo yokwelapha ngokweqile, ukucindezeleka kwegazi (calcium channel blockers), kanye namanye ama-antibiotics, ukuphumula kwemisipha kanye nezidakamizwa.
3) i-Vitamin D
I-Fibromyalgia kanye nama-aches nobuhlungu obukhulu abangahlangabezananga ne-diagnromatic criteria ye-fibromyalgia kuye kwashiwo abanye abacwaningi ukuthi banesifo se-vitamin D. Isibonelo, isifundo esikhulu saseJalimane sahlola abantu abangu-994 futhi sathola ukuhlanganiswa okuqinile phakathi kwamazinga aphansi e-vitamin D kanye namazinga aphezulu kanye nobude obude bomathambo jikelele kanye / noma ama-aches namahlunu.
Ucwaningo olunyatheliswa eMayo Clinic Proceedings luhlolisise abantu abangu-150 abanezinhlungu ezingapheli, ezingezona eziyinkimbinkimbi ye-musculoskeletal eMinnesota. Abacwaningi bathola ukuthi amaphesenti angama-93 awo ayenamazinga amancane kavithamini D.
Kwesinye isifundo, amazinga e-vitamin D ahlolwe abantu abangu-75 abagcwalisa i-American College of Rheumatology criteria ye-fibromyalgia. Nakuba kwakungekho ubuhlobo phakathi kwamazinga e-vitamin D nezimpawu ze-musculoskeletal, ukuntuleka kwe-vitamin D kwaxhunyaniswa nokukhathazeka nokucindezeleka kubantu abane-fibromyalgia.
4) 5-hydroxytryptophan (5-HTP)
Ukwengeza oku-5-HTP kucatshangwa ukuthi kusebenza ngamazinga akhula we-neurotransmitter serotonin ebuchosheni. Kukhona ubufakazi bokuqala bokuthi kunganciphisa inani lamaphuzu wethenda kubantu abane-fibromyalgia, mhlawumbe ngokufaka izinhlelo zokuhlukumeza ubuhlungu ku-brainstem.
Ucwaningo olulawulwa yi-doublebo blind, placebo lubuke u-5-HTP noma i-placebo kubantu abangu-50 abane-fibromyalgia. Ngemuva kwamasonto amane, abantu abathatha ama-5-HTP babe nokuthuthuka okuphawulekayo ebuhlungu, inani lamaphuzu wethenda, ukuqina, ukukhathazeka, ukukhathala nokulala. Imiphumela emibi yayimnene futhi ihamba isikhathi eside. Ukuze uthole olunye ulwazi, funda i-5-HTP Fact Sheet.
5) I-Vitamin B12
Ukutadisha kwaseSweden kwabonisa amazinga aphansi evithamini B12 emthonjeni we-cerebrospinal wabantu abane-fibromyalgia nesifo esingapheliyo sokukhathala.
Abesifazane abangu-12 abahlangabezana ne-fibromyalgia ne-chronic fatigue syndrome bafundiswa, kanye neqembu elilawulayo labesifazane abangu-18 abanempilo.
> Izinga le-homocysteine e-cerebrospinal fluid laliphindwe kathathu kulabo besifazane abanesifo se-fibromyalgia nesifo esingapheliyo sokukhathala uma kuqhathaniswa neqembu lokulawula. I-Cerebrospinal fluid vitamin B12 amazinga ayephansi kakhulu kubantu abangu-7 kwabangu-12 abane-fibromyalgia nesifo esingapheliyo sokukhathala.
6) I-Capsaicin Cream
I-Capsaicin (ebizwa ngokuthi i-cap-SAY-sin) iyisithako esisebenzayo ku-pepper. Kucatshangwa ukuthi kunciphisa okwesikhashana ubuhlungu.
Uma isetshenziswa esikhumbeni, ukhilimu we-capsaicin utholakale ekudambiseni imithi P, i-neurochemical ehambisa ubuhlungu, okwenzela umuntu ubuhlungu. Abantu abatholakala nge-fibromyalgia bathole ukuthi banezigaba eziphakeme P.
Olunye ucwaningo lwahlola ukusebenza kwe-capsaicin e-fibromyalgia. Abahlanganyeli ocwaningweni basebenzise u-0.025% we-capsaicin cream izikhathi ezine ngosuku ukuze amathenda amathenda. Emva kwamasonto amane, banciphise ubuhlungu. Ukuze uthole olunye ulwazi olufaka imiphumela emibi kanye nokukhathazeka kokuphepha, funda i- Capsaicin Cream Fact Sheet Sheet .
Ukusebenzisa izixazululo zemvelo ze-Fibromyalgia
Ngenxa yokuntuleka kocwaningo olusekelayo, kusheshe kakhulu ukutusa noma iyiphi enye indlela yokwelashwa kwe-fibromyalgia. Ngaphezu kwalokho, izithako azizange zivivinyelwe ukuphepha futhi ngenxa yokuthi izithako zokudla ezingenakulawulwa ngokomthetho, okuqukethwe kwemikhiqizo ethile kungase kuhluke kulokho okushiwo kwilebula lomkhiqizo.
Futhi khumbula ukuthi ukuphepha kwezidakamizwa kwabesifazane abakhulelwe, omama abahlengikazi, izingane, nalabo abanezimo zezokwelapha noma abaphuza imishanguzo abazange basungulwe. Ungathola amathiphu ekusetshenzisweni izithako lapha , kodwa uma ucabangela ukusetshenziswa kwemithi ehlukile, khuluma nomhlinzeki wakho wokunakekela oyinhloko kuqala. Ukwelapha isimo futhi ukugwema noma ukubambezela ukunakekelwa okujwayelekile kungaba nemiphumela emibi.
> Imithombo:
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> Erkal MZ, Wilde J, Bilgin Y, Akinci A, Demir E, > Bodeker > RH, Mann M, Bretzel RG, Stracke H, Holick MF. Ukukhuphuka okuphezulu kwe-Vitamin D, Ukwelashwa Kwesibili kanye ne-Generalized Bone Pain ku-Immigrants eTurkey eJalimane: Ukukhomba Izingozi Zezingozi. Ama-osteoporos Int. 17.8 (2006): 1133-1140.
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> Plotnikoff GA, Quigley JM. Ukuqhathaniswa kwe-Severe Hypovitaminosis D ezigulini eziphikisanayo, Ubuhlungu obungama-musculoskeletal obungapheli. I-Mayo Clin Proc. 78.12 (2003): 1463-1470.
> Regland B, Andersson M, Abrahamsson L, Bagby J, Dyrehag LE, Gottfries CG. Ukucabangela okuqhubekayo kwe-Homocysteine emzimbeni we-Cerebrospinal in Iziguli Eziphethe I-Fibromyalgia ne-Chronic Patigue Syndrome. Scand J Rheumatol. 26.4 (1997): 301-307.
> Tavoni A, Vitali C, Bombardieri S, Pasero G. Ukuhlolwa kwe-S-Adenosylmethionine ku-Fibromyalgia eyinhloko. Isifundo se-Double-Blind Crossover. Am J Med. 83.5A (1987): 107-110.
> Volkmann H, Norregaard J, Jacobsen S, Danneskiold-Samsoe B, Knoke G, Nehrdich D. Isifundo esinezimpumputhe ezimbili, IsiPhathimandla esilawulwa yi-Placebo-Control-Over-Intenvenous S-Adenosyl-L-Methionine ngeziguli ezine-Fibromyalgia. Scand J Rheumatol. 26.3 (1997): 206-211.
> Wahner-Roedler DL, Elkin PL, Vincent A, Thompson JM, Oh TH, Loehrer LL, Mandrekar JN, uBauer BA. Ukusetshenziswa Kwezokwelapha Ezihambisanayo Nezinye izindlela Abagulayo Ababhekiswe Kuhlelo Lokunakekelwa Kwe-Fibromyalgia esikhungweni sokunakekelwa kwezemfundo ephakeme. I-Mayo Clin Proc. 80.1 (2005): 55-60.
Ukwaziswa okuqukethwe kule sayithi kuhloswe ngezinhloso zemfundo kuphela futhi akusilo esikhundleni seseluleko, ukuxilongwa noma ukwelashwa udokotela olayisensi. Akuhloswe ukumboza zonke izinyathelo zokuphepha, ukusebenzisana kwezidakamizwa, isimo noma imiphumela emibi. Kufanele ufune ukunakekelwa okusheshayo kwezokwelapha kunoma yiziphi izinkinga zezempilo bese uthintana nodokotela wakho ngaphambi kokusebenzisa enye imithi noma wenze ushintsho ohlelweni lwakho.