I-Azelastine HCL ne-Fluticasone Propionate
I-Dymista (azelastine ne-fluticasone) iyinhlanganisela yemithi yama-nasal ene-azelastine hydrochloride (0.1%) kanye ne-fluticasone propionate (0.037%). Ifika emthamo wama-micrograms angu-50 (mcg) nge-spray ngayinye futhi isetshenziselwa ukuphatha izimpawu ezihlobene nezifo zonyaka.
Ngenxa yokuthi i-Dymista iyinhlanganisela ye-nasal inhlanganisela, izimpawu ezihlobene nezifo zonyaka zisondela ngokuxhumana ngezindlela ezimbili ezahlukene ngaphakathi komzimba.
Ingxenye yokuqala ku-Dymista, azelastine, ingumphikisi we-H1. Lolu hlobo lwemithi luvimbela imiphumela ye- histamine kuwo wonke umzimba futhi kusiza ukunciphisa ukukhululwa kwe-histamine. Umlando nabanye abalamuleli emzimbeni basisiza ekuphenduleni okweqile, ikakhulukazi ukuvuvukala. Ngokuvimbela i-histamine, i-Dymista ingakwazi ukukhulula ama-nasal amazwi "omzimba" ozwakalayo ohlobene nokuvuvukala. I-Azelastine ibuye iseze ekuthuthukiseni ukunyakaza kwe-cilia (izinwele ezincane ezibeka umzila wokuphefumula) emoyeni wakho, okusiza ekuthuthukiseni ukuhamba kwe-mucus.
Indlela yesibili ukuthi i-Dymista isisiza ukuxazulula izimpawu ezihlobene nezifo zonyaka zonyaka ngenxa yenkampani yesibili yenhlanganisela yama-nasal spray, i-fluticasone. I-Fluticasone iyi-corticosteroid, okuyiyona inguqulo yokwenziwa kwe-hormone ye-adrenal ngokwemvelo, i-cortisol. I-Corticosteroids isiza ukuvimbela imithwalo yegazi nokunciphisa ukuvuvukala emgodini wezintambo uma isetshenziswe kwifomu lefayili.
Zombili izenzo zisiza ekunciphiseni ukuxubana okuhlobene nezifo zonyaka. Isimo esibizwa ngokuthi ukuxubana kwe-rebound kuhlobene nokuphalaza okumanzi okuqukethe i-cortisone, kodwa-ke, ngakho kufanele uxoxisane nale ngozi ngodokotela wakho ngaphambi kokusebenzisa i-Dymista.
Indlela yokusebenzisa i-Dymista
I-Dymista isetshenziswe kuphela njenge-spray yangasese.
Isikhathi sokuqala oyisebenzisayo uzodinga ukuqala ipompo yeprayiphini ngokucindezela izikhathi ezingu-6 uze ubone i-spray emihle. Cishe uzodinga ukuphinda le nqubo uma ungayisebenzisi i-Dymista nasal spray yamaviki amabili.
Amathiphu okusebenzisa i-Dymista:
- Bamba ngobumnene ibhodlela le-Dymista nasal spray.
- Kubalulekile ukushaya ikhala lakho ukuze usule amavesi akho omzimba ukuze uthole imiphumela emihle.
- Hlela ikhanda lakho phansi ngenkathi uphonsela ekhaleni lakho.
- Qinisekisa ukugcina iphuzu le-nasal spray 1/4 kuya ku-1/2 amayintshi ekhaleni lakho ngenkathi ushaya.
- Ibhodlela kufanele libe lulungile lapho lifafaza.
- Vala enye i-nostril yakho bese ushaya ngokushesha ngemuva kokucindezela ipompo.
- Gwema ukufafaza uhlangothi lwendwangu yakho yomzimba phakathi kokubili amakha akho ukuze uthole imiphumela emihle.
- Sula elinye i-nostri ngendlela efanayo.
- Ngemuva kokusetshenziswa, uzodinga ukusula phezulu komfakisicelo uphinde ususe i-cap.
- Gwema ukuxhumana kwamehlo - uma ukuxhumana kwamehlo kuvela amehlo ehlanza imizuzu engu-10 noma ngaphezulu. Funa usizo lwezokwelapha uma kunesidingo.
I-Dymista Side-Effects
Imiphumela emibi kakhulu ehlobene nokusetshenziswa kwe-Dymista ihlanganisa:
- ukunambitheka okwenziwe
- ikhanda
- i-nosebleeds
- ukulala
I-Dymista ingabangela ukulala, ngakho kufanele uqaphele lapho usebenza noma yimiphi imishini noma ushayela uze wazi ukuthi umzimba wakho uphendukela kanjani emithini.
Kumele ugweme nezinye izidakamizwa ezifana nophuzo uma usebenzisa i-Dymista njengoba lokhu kungalimaza izinga lokuhleka noma ukulala. Ngenxa yokuthi i-Dymista iqukethe i-fluticasone, okuyi- corticosteroid , ukusetshenziswa okungapheli kungaholela ekususweni kwesistimu yakho ye-adrenal. Landela imiyalelo yokudokotela wakho wokulayela uma ufuna ukumisa le mithi. Ukunciphisa kungenzeka ukuthi kwenzeke uma usebenzisa le mithi kuhlanganise ne-Prednisone enezigidi ezingama-20 (mg) noma ngaphezulu. Ingxenye ye-fluticasone ye-Dymista nayo ingabangela ukulibaziseka emilenzeni yokuphulukisa emgqeni wakho wezandla futhi kubangele ukwanda noma ukuhlala isikhathi eside kwezifo.
Uma unomlando wokwanda kwengcindezi ye-intraocular, i-open-angle glaucoma, noma i- cataracts , kufanele ubone i-ophthalmologist bese uxoxisana nalokhu nodokotela wakho ngaphambi kokusebenzisa. Uma uthuthukisa noma yikuphi ukushintsha kombono ngesikhathi usebenzisa i-Dymista, kufanele uyeke ukusebenzisa i-spray ye-nasal uze uxoxisane ngokuqhubekayo nodokotela wakho kanye ne-ophthalmologist.
Ingabe i-Dymista ingafaki nezinye izidakamizwa?
Iningi lokuxhumana noDymista lihlobene nemithi ecindezela isimiso sakho sezinzwa noma ukusebenza kobuchopho. Lezi zihlanganisa ama-antihistamine, ama-anti-depressants, imithi yokulala kanye neminye imithi engabangela ukugubha njengomphumela wecala. Hlola nodokotela wakho lapho uqala imithi emisha.
Ngaphambi kokuthatha i-Dymista
Ngaphambi kokuba uqale i-Dymista, kufanele ubone udokotela wakho ubuyekeze umlando wakho wezokwelapha kanye nokubuyekeza imithi yakho yamanje. Ngokuyinhloko, udokotela wakho uzofuna ukwazi uma unesilonda emakhaleni akho, njengoba ukuphuza ukuphulukiswa kungenzeka ngokusetshenziswa kwe-Dymista. Uma uhlela ukukhulelwa kufanele ahlole ukuthi noma ngabe ukusebenzisa i-Dymista kufanele kugwenywe yini njengemithi yokwelapha Isigaba C.
Sebenzisa kuphela i-Dymista ngaphansi kokugunyazwa nodokotela uma ungavunyelwe, noma ungenayo inkukhu noma isirabhu ngoba iDymista ingandisa ukwanda kwezi zifo.
> Imithombo:
> UpToDate.com. I-Azelastine ne-Fluticasone: Ulwazi lwezidakamizwa.