Umehluko Phakathi kuka-Alzheimer's and Lewy Body Dementia

by U-Esther Heerema, i-MSW; Kubukezwe nguClaudia Chaves, MD

Ukuvama, Izimpawu, Izimbangela Nokuphila Okulindelekile kwe-LBD ne-AD

Isifo se-Alzheimer kanye ne-Lewy yokugula komzimba (LBD) yizo zombili izinhlobo zokuwohloka komqondo . Zinezinto eziningana ezifanayo, kodwa kukhona futhi umehluko ocacile phakathi kwezifo ezimbili.

Ukuvama

I-LBD: I- Lewy ye-dementia yomzimba iyinhlobo yesibili ejwayelekile kakhulu yomqondo wokugula komqondo, okulinganiselwa ukuthi abayizigidi ezingu-1.3 baseMelika abatholiwe.

I-Alzheimer's: Isifo se-Alzheimer yiyona ndlela evame kakhulu yokugula komqondo .

Kunezigidi ezingaphezu kwezigidi zaseMelika ezine-Alzheimer's disease.

Isizathu

I-LBD: Njengoba igama liphakamisa, i-Lewy yomqondo we-mental dementia ikholelwa ukuthi ibangelwa yi-builyp ye-Lewy yomzimba amaprotheni ebuchosheni.

I-Alzheimer's: I- Alzheimer's ibonakala ngamacwecwe e-amyloid nama- neurofibrillary tangles ebuchosheni. Abacwaningi basalokhu befuna izimpendulo ngokuthi yikuphi okubangela ukuthi lobu buchopho buguquke kokubili kwe-LBD ne-Alzheimer's, kodwa bahlonze izinto eziyisishiyagalolunye ezingozi ezikholelwa ukuthi zidlala indima ekubangela amacala amaningi e-dementia. Izindaba ezinhle ngalezi zinkinga ukuthi zingenye esingakwazi ukuzilawula ngokuncane.

Ukuqonda

I-LBD: Izimpawu nememori zingahluka ngokuphawulekayo ku-LBD, njengokuthi ngolunye usuku ugogo wakho ngeke akubone wena nangosuku olulandelayo, angakhumbula amagama omzukulu wakhe ngamunye.

I-Alzheimer's: Nakuba ukuqonda kungashintsha ngokungafani ku-Alzheimer's, ngokuvamile amandla omuntu okucabanga nokusebenzisa inkumbulo yakhe kancane kancane enqamula isikhathi.

Ngezimpawu ze- Alzheimer , ngokuvamile akuyona into enkulu kakhulu kusukela ngosuku olulodwa kuya kwesilandelayo.

Ukuhamba nokuhamba ngokomzimba

I-LBD: Ngokuvamile, esinye sezibonakaliso zokuqala ze-LBD kunzima ukuhamba, ukwehla kwesilinganiso kanye nokukwazi ukulawula ukunyakaza komzimba. Lezi zimpawu zifana nesifo sikaParkinson. Ukuwa njalo kubuye kuvamile ekuqaleni kweLBD.

I-Alzheimer's: Ukuwohloka komzimba ngokuvamile akuveli e-Alzheimer kuze kube yilapho lesi sifo sithuthukile kakhulu, ngaphandle kokuthi umuntu abe nezinye izifo noma izifo.

Isimo sobuso

I-LBD: Abanye abantu abane-LBD babonisa ukuthi bayathinteka, lapho ubuso babo bubonisa khona imizwelo emincane kakhulu. Lesi yisinye isibonakaliso esingase sibonise kusenesikhathi lesi sifo futhi sigqoke ngama- Parkinson .

I-Alzheimer's: Nakuba isibonakaliso sobuso siyancipha njengoba lesi sifo siphuthuka, lokhu kuvame ukuqhubeka kuze kube sezingeni eliphakathi kuze kube sekugcineni kwe-Alzheimer's .

Ama-Hallucinations okubukwayo

I-LBD: Ukuboniswa okubonwayo, lapho abantu bebona izinto ezingekho khona, zivame kakhulu ku-LBD. Lezi zihluthulelo zivela ngaphambili ekuqhubekisweni kwe-LBD.

I-Alzheimer's: I- Hallucinations iyenzeka ku-Alzheimer's, kodwa ngokuvamile ayiyona efana ne-LBD. Zibuye zenzeke ngezigaba kamuva zesifo se-Alzheimer, uma kuqhathaniswa nezigaba zangaphambili ze-LBD.

REM Sleep Behavior Disorder

I-LBD: Abantu abane-LBD ngezinye izikhathi babhekana nokukhubazeka kokuziphatha kwe-REM, ukukhubazeka lapho benza khona izimo emaphupheni abo. Olunye ucwaningo lubonisa ukuthi ukukhubazeka kokukhubazeka kwe-REM kungaba yinye yezibikezelo zangaphambili ze-LBD.

I-Alzheimer's: I- REM yokukhubazeka kokukhubazeka kwe-REM ngokuvamile ayikho ku-Alzheimer's, nakuba ezinye izinhlobo zokuphazamiseka kokulala zingase zenzeke.

Ukuzwela ku- Antipsychotics

I-LBD: Abantu abane-LBD banengozi enkulu yemiphumela emibi kakhulu uma kunikwa imishanguzo ye-antipyschotic. Ngokwe-Lewy Body Dementia Association,

"Iziguli ezingafika ku-50% ezine-LBD eziphathwa nganoma imiphi imithi yokulwa ne-antipsychotic ingase izwe ukuzwela okukhulu kwe-neuroleptic, njengokudambisa i-cognition, i-sedation esindayo, ukwanda kwe-parkinsonism noma okungenakwenzeka, noma izimpawu ezifana ne-neuroleptic syndrome eyingozi (i-NMS), engaba yingozi . (I-NMS ibangelwa ukukhulelwa okukhulu, ukuqina komzimba kanye nokuphazamiseka okungaholela ekuhlulekeni kwezinso.) "

I-Alzheimer's: Nakuba noma ubani othatha imishanguzo yokulwa ne - antipsychotic inengozi encane yokuthuthukisa i-neuroleptic malignant syndrome, abantu abane-Alzheimer's akuyona nje indlela yokuthuthukisa ukuzwela ngokweqile kwimishanguzo ye-antipsychotic ukuthi abantu abane-LBD babonise.

Ukunyuka kwezifo

I-LBD: Ngokusho kocwaningo oluqhutshwa nguJames E. Galvin, MD, MPH nabanye abacwaningi eWashington University School of Medicine, isikhathi sokuphila esiphezulu salabo abasesifundweni seLBD sineminyaka engu-78 ubudala, futhi kusinda ngemuva kokuqala kokugula komzimba kaLeyy kwaba iminyaka engu-7.3.

I-Alzheimer's: Esifundweni esicacisiwe ngenhla, isikhathi sokuphila esiphakathi kwabahlanganyeli abane-Alzheimer sika-84.6 ubudala, kanti izinga lokuphila ngemuva kokuqala kwezimpawu kwakungu-8.4 iminyaka. Kuye kwaphakanyiswa ukuthi umehluko ekuthuthukeni kwesifo phakathi kweLBD ne-Alzheimer's kungachazwa ngokunyuka ngokukhuphuka kokuwa, ngakho-ke ukulimala kanye nezibhedlela, kulabo abane-LBD.

Ubulili

I-LBD: Amadoda anethuba eliphakeme lokuthuthukisa i-LBD kunabesifazane.

I-Alzheimer's: Abesifazane banethuba elihle lokuthuthukisa i-Alzheimer's .

Izwi kusuka

Ukuqonda umehluko phakathi kwe-Lewy yomqondo wengqondo nokugula kwesifo se-Alzheimer kungasiza ukuhlukanisa phakathi kwezimo ezimbili futhi kukulungele izimpawu ezithile wena noma othandekayo wakho ongase azizwe. Ukwengeza, njengoba abanye abantu bevame ukujwayelana nesifo se-Alzheimer, kungaba usizo ukuchaza indlela i-Lewy yomzimba yokuwohloka komzimba okufana ngayo, futhi ehlukile, isifo se-Alzheimer's.

_Imithombo:

_{I-Dementia SOS: I-Colorado's Dementia News kanye Nesevisi Yesikhungo.} _{Umehluko phakathi kwe-Alzheimer's ne-Lewy yomqondo wengqondo yomzimba.} _{http://coloradodementia.org/2012/01/20/the-difference-between-alzheimers-disease-and-lewy-body-dementia/}

_{Emory University.} _{Isikhungo Sokucwaninga Nge-Alzheimer's.} _{Lewy Body Dementia.} > http://alzheimers.emory.edu/patients-caregivers/dementias/lewy_body_dementia/index.html

_{I-Lewy Body Dementia Association.} _{Izinketho zokwelapha.} _{http://www.lbda.org/content/treatment-options}

_{I-Lewy Body Dementia Association.} _{Ingabe I-LBD noma Into Ehlukile?} _{http://www.lbda.org/node/8}

_I-Neurology. _{Ukungqubuzana nokufa okungafani phakathi kwesifo sengqondo nomzimba we-Lewy nesifo se-Alzheimer.} > https://www.ncbi.nlm.nih.gov/pubmed/17159097