Ingabe i-Supplement CoEnzyme Q10 Ephumelelayo ekuvimbeleni kwe-Migraine?
I-CoEnzyme Q10-eyaziwa ngokuthi i-CoQ10-iyinto eyenzeka ngokwemvelo etholakala mitochondria cishe yonke iseli emzimbeni. I-Mitochondria yilawo magumbi wamaseli-ahlinzeka amandla adingekayo ukuze amangqamuzana emzimbeni asinde.
Ukwengezwa nge-CoQ10 kuye kwahlolwa ukuvimbela nokuphatha izifo eziningi ezihlukene, ikakhulukazi lezo ezihlobene nenhliziyo.
Kukhona nobufakazi bokuthi i-CoQ10 ingasiza ekuvimbeleni ukudluliswa kwamagciwane.
I-CoQ10 Inamandla Kanjani Ukuvimbela I-Migraines?
Ukungasebenzi noma inkinga nge-mitochondria yamaseli omuntu iye yaxhunyaniswa nokubunjwa kwe-migraine. Ngokukhethekile ezigulini ze-migraine, kungase kube khona ukungalingani phakathi kwama-oxidants kanye nama-antioxidants-okudala isimo sokucindezeleka okwenziwe nge-oxidative. Lokhu okungafani kahle kokusebenza kwamabhambo ku-brains of migraineurs kungabenza bavikeleke kakhulu ekuhloseni okuhlobene ne-migraine. Lezi zimo ezimbi kakhulu ze-metabolic nazo zinzima nakakhulu kwezinye izinhlobo ezihlukahlukene kakhulu ze-migraine, njenge- hemiplegic migraine .
Ngenxa yokuthi ukungalingani kwamangqamuzana akutholakali ngesikhathi sokuhlaselwa kwe-migraine, kodwa futhi phakathi kokuhlaselwa, ukwesekwa nge-CoQ10 (okunomsebenzi wokuvimbela i-antioxidant) kungathuthukisa ukungalingani kanye nokusetshenziswa kwamandla kagesi kwamaseli. Lokhu kuzosiza ukunqoba noma yikuphi ukukhubazeka kwe-mitochondrial futhi kungavimbela ukuguquka kwamagraines .
I-American American Headache Society kanye ne-American Academy of Neurology imihlahlandlela yokuvimbela i-episodic migraine ihluze i-CoQ10 njengesidakamizwa sezinga C noma "mhlawumbe esebenzayo" yokuvimbela i-migraine.
Ingabe i-CoQ10 Empeleni isebenza?
Akucacile kuleli phuzu. Izifundo ezincane ezimbalwa zikhomba ukuhlomula okungenzeka kwe-CoQ10 ekunciphiseni inani lokuhlaselwa kwe- migraine .
Ngokwesibonelo, esifundweni esisodwa esincane se-2005 ku- Neurology, iziguli ezingama-43 ezine- migraines ezingenayo ne- auras zithole ama-100mg we-CoQ10 noma iphilisi ye-placebo kathathu nsuku zonke izinyanga ezintathu. Phakathi naleso sifundo, abahlanganyeli babhala izici ze-migraine yabo kudayari kubandakanya:
- ubuhlungu bekhanda
- Isiyaluyalu / ukuhlanza
- imishanguzo eqinile ye-migraine
- ubude bekhanda
Imiphumela yocwaningo yabonisa ukuthi abantu abathatha i-CoQ10 babe namaphesenti angu-50 noma ukwehla okungaphezulu kwenani lokuhlaselwa kwe-migraine ekupheleni kwezinyanga ezingu-3 kuqhathaniswa nabantu abathatha indawo ye-placebo.
I-CoQ10 yayibekezeleleke kahle iningi labahlanganyeli umuntu oyedwa waphumela ngenxa yesikhumba sofuba.
Yiziphi Imithombo ye-CoQ10?
Ukudla okuqukethe i-CoQ10 kubandakanya izinhlanzi ezinamafutha (njenge-saumoni noma i-tuna) inyama yenyama, kanye nezinhlamvu ezigcwele. I-CoQ10 iyatholakala emafomu amaningi okufakazela. Esinye isici esicindezelayo se-CoQ10 ukwengezwa yi-profile side effect effect-ne-ejwayelekile kunazo zonke iziyaluyalu, isifo sohudo, ukunciphisa ukudla, ukuphuza umoya, nokuhlukunyezwa kwesisu.
Ngokuvamile, qiniseka ukuthi uthintane nodokotela wakho ngaphambi kokuba uzame ukwesekwa okunomsoco, ikakhulukazi kusukela i-CoQ10 ixhumana nemithi eminingi.
Ngaphansi
Amanye ama-migraine angase ahlanganiswe nezinkinga ezine-mitochondria yamaseli.
Ucwaningo oluthe xaxa ku-CoQ10 nakweminye imithi yokwenza ngcono umsebenzi we-mitochondrial kungasiza.
Imithombo:
Loder, E., Burch, R., & Rizzoli, P. (2012). Imikhombandlela ka-AHS / AAN ka-2012 yokuvimbela i-Epradic Migraine: Ukufingqa kanye nokuqhathaniswa nezinye iziqondiso zomtholampilo zakamuva. Inhloko, 52: 930-45.
ULucchesi, C. (2015). Ubufakazi bokuthi umsebenzi we-Antioxidant owehlisiwe wezisebenzi ezigulane ezine-Chronic Migraine kanye neMithi-Ukusetshenziswa kwekhanda lokusebenzisa kabi. Inhloko, 55 (7): 984-91.
Markley, HG (2012). I-CoEnzyme Q10 ne-Riboflavin: Ukuxhuma kwe-Mitochondrial. Amakhanda, u- 52 Uku-2: 81-7.
Rozen, TD, et al. (2002). I-Label ye-Open Open ye-Coenzyme Q10 njenge-Prevention Migraine. I-Cephalalgia, 22 (2): 137-41.
Sándor, PS, et al. (2005). Ukusebenza kwe-Coenzyme Q10 ku-Migraine Prophylaxis: Isivivinyo Esilawulwe Ngokungahleliwe. I-Neurology , 22; 64 (4): 713-5.
I-Tepper, i-SJ, i-Rapoport, i-A., ne-Sheftell, F. (2001). I-Pathophysiology ye-Migraine. I-neurologist, 7 (5): 279-86.
Isikhungo Sezokwelapha sase-University of Maryland. (Kubukeziwe ngo-2015). CoEnzyme Q10.
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