Thola ngezinye zezifo ezihlukahlukene zesifo se-Alzheimer's
I-ApoE 4 ingenye yezinhlobo ezihlukahlukene ze-apolipoprotein E (ApoE) gène. Ngokusho kwe-Alzheimer's Action Plan, labo abane-gene E-ApoE 4 banamathuba amathathu kuya kweziyisishiyagalombili amathuba okuthuthukisa i- Alzheimer's disease kunelabo abangathwali i-ApoE 4. Izinga lezingozi ngokuyincike kuncike ekutheni umuntu uzuza iphimbo elilodwa noma amabili isakhi, edlala indima ekusebenzeni kwe-cholesterol.
Ingabe kukhona ukuhlolwa kwe-ApoE?
Yebo, kukhona ukuhlolwa kwegazi okungakwazi ukubona ukuthi ungathwali izakhi ze-ApoE noma cha. Kodwa-ke, ngenxa yokuthi unegesi akusho ukuthi uzokwenza noma ngeke uhlakulele isifo se-Alzheimer . Ukuvivinya izifo ngeke kubikezele ukuthi iziphi izifo eziyokwenzeka ngoba kunezinye izici eziningi - imvelo nokuphila kukhona ezimbili - ezithinta ukuqhubeka nokuthuthukiswa kwezimo zezempilo.
Yebo, kukhona ukuhlolwa; kodwa ngaphandle kokuthi uhlanganyele ekuvivinyweni komtholampilo kanti udokotela wakho uzama ukuxilonga ukuqala kokuqala kwesifo se-Alzheimer, akunconywa. (Nazi izinzuzo ezingu - 12 zokuxilonga kwesifo se-Alzheimer ekuqaleni .) Ukuhlolwa kusetshenziselwa ukucwaninga okwenziwa ngabacwaningi abangaba nengozi enkulu yokuthuthukisa i-Alzheimer's. Kulesi simo, ososayensi bangabheka ukuthi ubuchopho buyashintsha kanjani nokuthi izindlela zokwelashwa zisebenza kanjani. Njengamanje, akukho ulwazi olwanele lokuqinisekisa ukuhlolwa kwe-ApoE kubo bonke, noma ngempela labo abanomlando womndeni wesifo.
Faka ku-Research Alzheimer
Kukhona amaphrojekthi amaningi abheka indlela izakhi zofuzo ezithinta ngayo ukuguquka kwezifo, ikakhulukazi njengoba kuhlobene nesifo se-Alzheimer's. Ukuze lezi zifundo ziphumelele futhi zigcwale ulwazi oludingekayo ukulwa nalesi sifo, izisebenzi zokuzithandela zibalulekile.
Ukuze ufunde kabanzi mayelana nezifundo zofuzo ze-Alzheimer, xhumana ne-National Cell Repository ye-Alzheimer's Disease (NCRAD) mahhala ku-1-800-526-2839 noma uvakashele i-http://ncrad.iu.edu.
Ukuze ufunde kabanzi mayelana nokuzinikela kokuhlolwa kwe-Alzheimer's and trial studies, vakashela ku-www.nia.nih.gov/alzheimers/volunteer.
Yini okufanele uyenze uma unegesi
Isayensi isanda kuqala ukuthola ukuthi isakhi se-ApoE 4 sithonya kanjani ukuthuthukiswa kwesifo se-Alzheimer. Lokhu kusho ukuthi akucaci ukuthi yini engenziwa ukuze imise lokhu kuqhubekela phambili. Kodwa kunemininingwane ethile. Ngokwesibonelo, ngo-February 2016 isifundo esanyatheliswa kuyi- Journal of the American Medical Association , abacwaningi bathola ukuthi ukusetshenziswa kwezilwane zasolwandle okulinganiselwe kwakuhlotshaniswa ne-Alzheimer's disease neuropathology encane. Kukhona nobufakazi obuningi obuxhumanisa kakhulu ithusi kanye ne-zinc ekudleni ukuze kungene ingozi yesifo se-Alzheimer kanye nesifo sengqondo somqondo.
Futhi, ukuzivocavoca. Ukuze uthole ukuthi ukusebenza komzimba kuthinta kanjani ubuchopho bakho, bheka ucabange ukufunda:
Izindlela ezingu-6 ezenziwa ngokomzimba zingasiza isifo se-Alzheimer's
Ukuzivocavoca okunye okuvimbela phambili nokunciphisa i-Alzheimer's
Izindlela ezingu-10 zokunciphisa ingozi ye-Alzheimer's disease
Imithombo
UMorris MC, u-Brockman J, u-Schneider JA, u-Wang Y, i-DA ye-Bennett, i-Tangney CC, i-van de Rest O. i-Association of Seafood Consumer, i-Brain Mercury Level, i-APOE ε4 Isimo Ne-Brain Neuropathology ku-Older Adult. I-JAMA. 2016 Feb 2; 315 (5): 489-97. doi: 10.1001 / jama.2015.19451.
Isifo Se-Alzheimer's Genetics Fact Sheet. Izikhungo Zempilo Zesizwe: Isikhungo Sikazwelonke Sokuguga. Ifinyelele ngo-Mashi 2, 2016.