Ukubuyekezwa Kwezimbangela, Ukuxilongwa Nokuphathwa Kwe-Eosinophilia
I-Eosinophilia yigama lobuchwepheshe lokubalwa kwe-eosinophil. Ama-eosinophils awuhlobo lwamaseli amhlophe egazi abhubhisa izinto emzimbeni njengama-parasites futhi abambe iqhaza ekusebenzeni kwe-allergenic.
Yiziphi Izimbangela Ze-Eosinophilia?
Kunezizathu eziningi izibalo zakho ze-eosinophil zingase ziphakanyiswe. Ezinye zezimbangela ziyingozi futhi zidinga ukwelashwa okuncane.
Kuyinto engavamile ukuthi inani eliphakeme libe yisikhathi eside futhi lixazulule ngaphandle kokwelashwa. Ake sibuyekeze ezinye zezimbangela manje.
- Ukutheleleka kwama-parasite: Emhlabeni jikelele imbangela evamile kakhulu ye-eosinophilia yi-infection ye-parasite. Amagama alawa ma-infections ahlanganisa i-schistosomias, trichinosis, strongyloidiasis, ne-ascariasis. Lezi zinambuzane zingatholakala emhlabeni jikelele kubandakanya i-United States. Umlando wokuhamba uyingxenye ebalulekile yomsebenzi we-eosinophilia nakuba ukungabi khona kwehambo lwakamuva akukhipha izifo ezithathelwanayo. Uhudo lwabagibeli luhlobo lokutheleleka kwamagciwane kodwa aluvamile ukuhlotshaniswa ne-eosinophilia.
- Ukusabela kwezidakamizwa: Imithi ingabangela i-eosinophilia, ngezinye izikhathi ngaphandle kwempawu noma izimpawu ezicacile. Imithi ejwayelekile kakhulu ehlobene ne-eosinophilia ihlanganisa ama-antibiotics (i-penicillin, i-cephalosporins), imishanguzo engeyona i-steroidal anti-inflammatory (aspirin, ibuprofen), i-ranitidine (ye-reflux ye-gastroesophageal), i-phenytoin (i-anti-seizure) ne-allopurinol (esetshenziselwa ukuphatha igciwane). Ifomu elibi kakhulu libizwa ngokuthi ukusabela kwezidakamizwa nge-eosinophilia kanye nezimpawu zesistimu (DRESS). Ngenhlanhla, iningi labantu ngeke libe nalezi zindlela uma zithola le mithi.
- I-Atopy : I-Atopy iyisabela esithile esenzeka emzimbeni. Ngokujwayelekile, i-atopy ibhekisela ku-asthma, imilayezo yonyaka (ebizwa ngokuthi i-allergenic rhinitis), ne-eczema. Akuvamile ukuthi othile abe nezimo ezingaphezu kweyodwa kulezo zidakamizwa njengoba zihlobene. Lezi ezinye zezimbangela ezivame kakhulu zokunakekelwa kwe-eosinophilia emincane, ikakhulukazi ezinganeni. Ngokufanayo, ukudla kokudla kungabangela nokubala okuphakeme kwe-eosinophil.
- I-Eosinophilia esophagitis (EoE): Lesi yisiyaluyalu esibonakala yi-eosinophils esakazeka emgodleni ovame ukungenawo ama-eosinophils. Abantu abangaba ngu-50% abane-EoE nabo bayobe bephakamisa izibalo ze-eosinophil egazini.
- Ama-hyndereosinophilic syndromes : Ama-syndromes ama-hyperoeosinophilic (HES) yiqembu lezinkinga ezivezwe ngokubala okuphezulu kakhulu kwe-eosinophil nobufakazi bokulimala komzimba kusuka enombolweni enkulu ye-eosinophils. Amalungu avame ukuhlosiwe yilezi zesikhumba, emaphaphu, kanye nasemathunjini emathunjini. I-HES ingaba yiphambili (ebizwa nangokuthi i-neoplastic) yesibili (esebenzayo) noma idiopathic (imbangela engaziwa).
- I-Churg-Strauss Syndrome: i-vasculitis ye-Churg-Stauss, ebizwa ngokuthi i-eosinophilic granulomatosis nge polyangiitis, ingabangela i-eosiniophilia. Abantu abanalesi sifo babekhona nge-asthma nakwezinye izinkinga zamaphaphu ekuqaleni, bese kuthuthukisa i-eosinophilia, futhi ekugcineni i- vasculitis , ukuvuvukala kwemithambo yegazi.
- Amanqamu: Kunezifo eziningana ze-cancers, ikakhulukazi i-blood cancers, eyaziwa ngokukhulisa inani le-eosinophil. Lezi zihlanganisa uhlobo olungavamile lwe-lemonemic leukemia (AML) ebizwa ngokuthi i-eosinophilic leukemia. Ezinye izimbangela zihlanganisa amaningana we- myeloproliferative neoplasms (njengokuthi, i-thrombocythemia ebalulekile, i-polycythemia vera) i-B-cell ne-T-cell lymphoma, kanye ne-adenocarcinomas yegciwane lesisu, umaphaphu nomlomo wesibeletho.
Ziyini Izimpawu Ze-Eosinophilia?
Uma une-eosinophilia, izimpawu zakho zizobekwa eceleni ngokubangela imbangela ye-eosinophilia count count. Uma isibalo sakho se-eosinophil sinyanyiswa kahle ungase ungabi nazo izimpawu. Izimpawu ezivamile zihlanganisa:
- Rash
- Itching
- Isifo sohudo, esimweni sezifo ezithathelwanayo
- I-asthma
- Iphutha le-Runny, ikakhulukazi uma lihambisana ne-allergies.
I-Eosinophilia Iqhathaniswa Kanjani?
Njengezinkinga eziningi zegazi, i-eosinophilia ibonakala ngokubala okuphelele kwegazi (i-CBC) . I-Eosinophils ingenye yamangqamuzana egazi elimhlophe futhi itholakala engxenyeni ye-CBC ebizwa ngokuthi umehluko. Ukuhlukana kubika ukuthi zingaki izinhlobo zohlobo olulodwa lwamaseli amhlophe wegazi (neutrophil, lymphocyte, monocyte, eosinophil, ne- basophil ) zikhona egazini.
Ngemuva kokuhlonza i-eosinophilia, umhlinzeki wakho wezempilo uyoqala ukusebenza ekuboneni imbangela, ngezinye izikhathi lokhu kudinga ukuthunyelwa ku-hematologist. Ubukhulu be-eosinophilia ngezinye izikhathi kungabangela umsebenzi odingekayo. I-Eosinophilia ingahlukaniswa inani le-eosinophils (inani eliphelele le-eosinophil).
- Ubumnene: 500 - 1500 amaseli / mL
- Okulinganiselwe: 1500 - 5000 amaseli / mL
- Okukhulu:> 5000 amaseli / mL
Ukunquma imbangela ye-eosinophilia yakho kuyobe kusekelwe ezimpawu zakho. I-Eosinophilia isophagitis ingabangela ubunzima ukugwinya, isifuba kanye / noma ubuhlungu besisu, ukuhlanza noma ukudla okunamathela endaweni. Ukuxilongwa kudinga i-biopsy ye-esophagus. Izifo eziningi ze-parasite zitholwa ngokuthatha amasampuli esitokisini nokuzihlola. Kungase kungabi nhlobo ukuhlolwa ukuthola ukuthi imithi iyimbangela ye-eosinophilia yakho. Uma isibalo sakho se-eosinophil sibuyela esimweni esijwayelekile emva kokuyeka imithi, ngokuvamile kubhekwa ukuthi imithi yayiyimbangela.
Yiziphi Izinyathelo Zokwelapha Ze-Eosinophilia?
Ngokufanayo nalokho okuhloswe ngakho okudingekayo, ukwelashwa kunqunywa imbangela ye-eosinophilia. Izinketho zihlanganisa:
- Ukubheka: Uma i-eosinophilia yakho ibumnene, ukubonwa ngama-labs okuphinda kungase kunconywe.
- Uma imithi ibangela isibalo sakho se-eosinophil esiphezulu, singase siphelelwe
- Ukwandisa ukwelashwa kwesifo se-asthma, i-eczema, nesifo somzimba
- Izifo ze-parasite ziphathwa ngemithi ephikisayo.
- I-steroids njenge-prednisone ingase isetshenziselwe ukwelapha i-hypereosinophilic syndromes
Izwi elivela
I-Hypereosinophilia yigama elizwakalayo elizwakalayo. Ngenhlanhla, kubantu abaningi abanalesi simo, sekuyisikhathi eside futhi kudinga ukwelashwa okuncane. Kwabanye, ukuxilongwa kanye nokwelapha kungadinga ukuthunyelwa kuchwepheshe. Uma unenkinga eyengeziwe, qiniseka ukuthi uxoxe nabo nodokotela wakho.
> Umthombo:
> I-Weller PF neKlion AD. Indlela eya kwesiguli nge-eosinophilia engachaziwe. Ku: Phezulu, I-post TW (Ed), UpToDate, Waltham, MA.