Ukuqonda izimbangela, Impact, kanye nokwelapha
I-Vitamin D iyisisindo esibalulekile sezempilo yethambo, i-calcium balance, nokusebenza komzimba- kodwa ngokuvamile kubonakala sengathi iphansi kubantu abaningi abane-HIV. Ngenkathi izizathu zalokhu zingaba ziningi, kucacile ukuthi ukutheleleka nge-HIV, futhi kuqobo, kubangele kulokhu futhi ukuthi ukulahlekelwa okuqhubekayo kungaba nomthelela omubi empilweni yakho yesikhathi eside.
Sitholaphi i-Vitamin D yethu?
I-Vitamin D ingenye yamavithamini amanama omzimba omzimba.
Ngokungafani namanye amavithamini, atholakale emithonjeni embalwa yokudla - njengezinhlanzi ezithile nokudla okuqinisiwe, njengobisi nezinhlamvu. Iningi lamavithamini D lenziwa emzimbeni wethu ngemva kokushiswa kwelanga.
Lapho isikhumba senyama yethu sibhekene nemisebe yelanga yelanga, i-molecules efana ne-cholesterol ikhishwa egazini, yenza indlela eya esibindi. Ngesinye isibindi esesibindi, siphenduka sibe yi- 25-hydroxyvitamin D. Le moleksi iyahamba iya ezinso lapho iguqulwa ibe yi- 1,25 dihydroxyvitamin D , ifomu elisebenzayo lamavithamini D.
Umuntu angathola futhi i-Vitamin D ezivela ezakhiweni, njenge-vitamin eyodwa noma njengengxenye ye-multivitamin. Kukhona nemigomo ye-vitamin D enikezwe iziguli ezithile ezinezifo ezibabeka phambili ukuba babe namazinga aphansi e-vitamin D.
Kungani Abantu Beba I-Vitamin D Abenele?
Kunezizathu eziningi zokuthi kungani umuntu engase abe nokutholakala kwe-vitamin D. Kwabanye abantu, izifo ezithile zixhunyaniswa nesimo, njengezibindi nesifo sezinso - ngoba isibindi nezinso zezinso zibalulekile ekutheni umzimba usebenzise u-vitamin D emzimbeni.
Izifo ze-Celiac , noma ezinye izifo ezivimbela ukumunwa okufanele kwevithamini D emanzini, zingabangela nokuntuleka kwe-vitamin D.
Abantu abathola ukukhanya okuncane kwelanga kanye / noma ukudla okunomsoco omncane ku-vitamin D bangase bathuthukise nokuntuleka kwe-vitamin D. Lokhu kuvame kakhulu kubantu asebekhulile abahlala emakhaya asebekhulile.
Ukukhuluphala kanye nemithi ethinta indlela i-vitamin D eyenziwa ngayo emzimbeni, njengemithi ethile yokulwa ne-anti-seizure , ingase ibe nomuntu obhekene nokuntuleka kwe-vitamin D.
Kuyini ukuxhumeka phakathi kwe-HIV ne-Vitamin D?
Ngokwesifundo se-2012 ku- Journal of Antimicrobial Chemotherapy, abantu abangaphezu kwamaphesenti angu-85 abantu abanesandulela ngculaza banamazinga aphansi e-vitamin D - isizathu esiqondile sokuthi kungani leli phesenti liphakeme kakhulu.
Ngaphezu kwalokho, kukhona ubufakazi besayensi obonisa ukuthi imithi ethile ye-antiretroviral, iphazamisa indlela i-Vitamin D eyenziwa ngayo emzimbeni. Lokhu kungabangela ukutholakala kwevithamini D kubantu abanesandulela ngculaza.
Kulawa, uSustiva (efavirenz) uthathwa njengomsolwa oyisisulu, kanye nanoma iyiphi imithi yokuhlanganisa (isib. I-Atripla) equkethe i-efavirenz. Njengamanje, akekho omunye umuthi we-antiretroviral oye wabonisa leli zinga lokuhlangana ne-vitamin D ukuntuleka.
Ukutholakala kweVithamini D kutholakala kanjani futhi kuthathwa kanjani
Ngokulinganisa inani lama-25-hydroxyvitamin D egazini, udokotela anganquma ukuthi umuntu unevithamini D eyanele emzimbeni wakhe.
Ngenhlanhla, kunendlela elula yokubuyisela imithi ye-vitamin D - ngokuthatha izithako ze-vitamin D. Udokotela angakwazi ukubala umthamo owulungele wona - umthamo ovamile owenziwe ngu-50,000 IU we-vitamin D owathathwa ngomlomo kanye ngesonto ngalinye amasonto angu-8.
Ngemuva kokubuyisela izinga le-vitamin D, udokotela uzobeka umthamo we-400 kuya ku-800 IU we-vitamin D3 ethathwe ngomlomo ngosuku. Abanye ochwepheshe basikisela ukuthi amazinga aphezulu kavithamini D adingeka nsuku zonke ukuze alondoloze ibhalansi enempilo.
Ukuphulukiswa kwe-Vitamin D kuvame ukuphakanyiswa lapho amazinga ka-25-hydroxyvitamin D ewela ngaphansi kuka-10 ng / ml.
Kubalulekile ukuqaphela ukuthi nakuba ukutholakala kwe-Vitamin D kuhlobene nokukhanya kwelanga, kubalulekile ukuthi umuntu azivikele emisebeni yelanga elonakalisayo, njengoba kunconywe yi-American Academy of Dermatology.
Ngenzeni?
Lapho uvakashele udokotela wakho ozayo, khuluma naye nge vithamini D.
Qinisekisa ukuthi ukusilela akuyona inkinga kuwe, nokuthi wenza konke okusemandleni akho ukuze ugcine izinga eliphilile lala vithamini ebalulekile.Uma usuvele uthatha noma yiziphi izithako, qiniseka ukuthi uneluleka udokotela wakho ngalokhu, kanye nanoma yikuphi ezinye izidakamizwa, imithi kadokotela noma cha, ungase uthathe.
Imithombo:
I-Allavena C et al. "Imvamisa ephezulu ye-vitamin D enesifo esinegciwane lesandulela ngculazi: imiphumela yezinto ezihlobene ne-HIV nemithi elwa negciwane lesandulela ngculaza". J Antimicrob Chemother. 2012 Sep; 67 (9): 2222-30.
Cannell, JJ, Hollis BW, Zasloff M, Heaney RP. "Ukuxilongwa Nokunakekelwa Kwe-Vitamin D" .Expert Opin Pharmacother2008 Jan; 9 (1): 107-18.
I-Pinzone MR. "Ukuntuleka kweVithamini D ekutheleleni kwegciwane lesandulela ngculazi: isifo esingenakulinganiswa nesingaphansi kwesifo". I-Eur Rev Med Pharmacol Sci. 2013 Meyi; 17 (9): 1218-32.
I-Yin M. "I-Vitamin D, ithambo, ne-HIV." I-Med Okumnandi Kakhulu. 2012 Dec; 20 (5): 168-72.