I-hypothalamus yingxenye ebalulekile yesistimu yakho ye-neuroendocrine. Ilawula ukuxhumana phakathi kwesistimu yakho yokukhiqiza i-endocrine noma i-hormone kanye nezingxenye ezithile zesistimu yakho yezinzwa. I-hypothalamus yakho inesibopho sokukhiqiza i-hormone edala ukuqala komjikelezo wakho wokuya esikhathini.
Uphi i-Hypothalamus?
Uma udweba umugqa phakathi kwamashiya akho emuva ngqo enkabeni yobuchopho bakho uzothola isakhiwo se-pea esibizwa nge-hypothalamus.
Lokho okuyingxenye yobuchopho ayinakho ngobukhulu okwenzelwe ukusebenza.
Iyini i-Hypothalamus?
Cabanga nge-hypothalamus njenge "smart system control system" yomzimba wakho. Umthwalo wayo oyinhloko ukugcina umzimba wakho usebenza kahle futhi uzinzile. I-hypothalamus ilawula futhi iqondisa okuningi kwemisebenzi yakho yokuzibophezela yomzimba njengomthetho wokushisa, indlala, ukoma, ukulala nokuzizwa. Ngokwenza ngokuphendula okuvela ebuchosheni nakwezinye izikhungo zokukhiqiza i-hormone emzimbeni, i-hypothalamus ilungisa ibhalansi yangaphakathi yomzimba noma i-homeostasis.
Olunye umsebenzi obalulekile we-hypothalamus ukulawula igundane le- pituitary . I-hypothalamus ikhiqiza izinto ezibizwa ngokuthi ukukhulula ama-hormone asebenze i-pituitary gland ukukhuthaza ezinye izingxenye zokukhiqiza ze-hormone zomzimba wakho njenge-thyroid kanye ne- ovary . Ngokulawula ukukhululwa kwama-hormone, i-hypothalamus nayo ihileleke ngokuqondile nomzimba wakho wokukhula komzimba, ukukhula, ukushayela ucansi, kanye nokujikeleza kwakho kokuya esikhathini.
Ukulawula Ukuhamba Kwesikhashana
I-hypothalamus yakho ikhiqiza ihomoni ebizwa nge-GnRH noma i-gonadotropin ekhulula i-hormone. Ngaphansi kwezimo ezijwayelekile, umzimba wakho ukhulula i-GnRH ngendlela ephathekayo. Lokhu kukhululwa okuyisisusa kubangelwa ukuthi i-pituitary gland iqondise ukukhululwa kwamanye ama-hormone amabili okuthiwa i-FSH noma i-follicle evuselela i-hormone ne-LH noma i-hormone yokuqondisa.
I-FSH nayo ikhuthaza i-ovary ukukhiqiza i-estrogen ne-LH igqugquzela i-ovary ukukhiqiza i-progesterone. Izinguquko ezishintshashintshayo zama-hormone zithinta umjikelezo wakho wokuya esikhathini ohlanganisa kokubili ukuvota futhi uma kungekho ukukhulelwa noma ukukhulelwa kwenzeka, ukuya esikhathini noma isikhathi sakho.
Lapho Izinto Zihamba Ngalungile
Njengoba i-hypothalamus iyinhlangano yokulawula yokujikeleza kokuya esikhathini, izimo ezithile eziphazamisa ukulinganisela komzimba futhi ziphazamise ukusebenza kahle kwe-hypothalamus nazo zingaphazamisa umjikelezo wakho wokuya esikhathini. Lapho ukukhululwa kwe-GnRH kungenzeki ngendlela evamile ye-pulsatile, i-FSH ne-LH ayitholakali kahle nge-pituitary gland. Ngaphandle kokugqugquzela kula ma-hormone, ama-ovari awakhiqizi i-estrogen ne-progesterone ne-ovulation ayikho. Ngaphandle kokuvuthwa, akukho ukuya esikhathini.
Ithimba lobuchwepheshe lokulahlekelwa isikhathi sakho i-amenorrhea noma ngokoqobo ngaphandle kokuphuma kwegazi. Uma ulahlekelwa isikhathi sakho ngoba i-hypothalamus yakho ayisebenzi ngendlela evamile ibizwa ngokuthi i-hypothalamic amenorrhea. Izimbangela ezivamile ze-hypothalamic amenorrhea zihlanganisa:
- ukucindezeleka kwengqondo
- ukucindezeleka ngokomzimba
- isifo esingapheliyo
- ukuzivocavoca ngokweqile
- ukulahlekelwa kwesisindo ngokweqile
I-amenorrhea ye-hypothalamic iyimbangela evamile yezikhathi ezingekho.
Kuncike ekutheni ubude nokucindezeleka emzimbeni wakho ungaphuthelwa isikhathi esithile noma ungayeka ukuya esikhathini.
Ukulawula Isikhungo Solawulo
Ukuqonda ukubaluleka kokukhululwa kwe-GnRH okuphakathi kwalabo abacwaningi be-hypothalamus abaholele ukuthuthukisa uhlobo lwemithi eyenza ukukhiqizwa kwama-ovaries okwesikhashana kwe-estrogen ne-progesterone. Ukugcina izinga elijwayelekile le-GnRH ekusakazweni kwegazi linciphisa ukukhululwa kwe-pshitary ye-FSH ne-LH ephikisana nokukhiqiza ukukhiqizwa kwama-ovarian we-estrogen ne-progesterone. Leli klasi lemithi eyaziwa ngokuthi i-gonadotropin-ekhulula i-hormone agonists ihlanganisa i-leuprolide acetate noma i-Lupron ne-goserelin acetate noma i-Zoladex.
Le mithi inendima ebalulekile ekwelapheni izimo eziningana zokubeletha njenge-uterine fibroids ne-endometriosis.
Izwi elivela
Ngezinye izikhathi ulahlekelwa yisikhathi sakho kungase kube nje impendulo evamile yomzimba wakho ekucindezelekeni. Kodwa ukulahlekelwa isikhathi sakho ikakhulukazi izinyanga ezimbalwa ezilandelanayo kungaba uphawu lwezinkinga ezingaphansi noma ukungalingani emzimbeni wakho.
Njengoba njalo, uma ubhekana nezinkinga ezinomjikelezo wakho wokuya esikhathini sicela uxoxisane nomhlinzeki wakho wezempilo.
Kubuyekezwe ngu: Andrea Chisholm MD
> Umthombo:
> I-Reed BG, i-Carr BR. Umjikelezo Ojwayelekile Wokuhamba Kwesimiso Nokulawulwa Kwe-Ovulation. [Kubuyekezwe ngo-2015 Meyi 22]. Ku: De Groot LJ, Chrousos G, Dungan K, et al., Abahleli. I-Endotext [I-intanethi]. South Dartmouth (MA): MDText.com, Inc .; 2000-.Itholakala kusuka: https://www.ncbi.nlm.nih.gov/books/NBK279054/