I-Skin Patch Isebenza njenge-Dopamine Agonist, Kungathi Kungabangela U-Rashes
Isiqephu se-Neupro imithi yokwelapha, edayiswa ngaphansi kwegama elivamile le-rotigotine transdermal, elisetshenziselwa isikhumba futhi lingasetshenziswa ukuphatha izimpawu zesifo sikaParkinson kanye nesifo sezinyawo ezingenalutho (RLS) noma isifo se-Willis-Ekbom. Isiqephu se-Neupro sisebenza kanjani? Yimiphi eminye imiphumela emibi neyingozi? Funda mayelana nokusetshenziswa kwe-Neupro ukuphatha lezi zimo ze-neurological and sleep, kuhlanganise nezindleko, ukubeka indawo, nokuxwayisa.
Ukusebenzisa i-Neupro Patch yokuphatha ukuphumula kwama-Syndrome
I-Neupro iyi-patch ye-prescription engasetshenziselwa ukuphatha isifo sika-Parkinson futhi ihlolisise ukuze ibe ne-severe RELS syndrome. Isifo sikaParkinson sibonakala ngokuphumula, ukuqina noma ukuqina, ukuhamba kancane, nokungazinzi okulandelayo okuholela ekuweni. I-RLS iqukethe ukuzwa okungakhululekile noma okungavumelani okuhlotshaniswa nesifiso sokuhambisa lokho okwenzeka kaningi uma ulala phansi kusihlwa. Ukuhamba kwezimpawu kusikhulula lesi senzo esingakhululekile. Ngalinye yalezi zimo ezihlukile kubangelwa ukungajwayelekile okuhlobene ne-dopamine.
I-Neupro Patch isebenza kanjani?
Isiqephu se-Neupro sisebenza ngokugqugquzela i-dopamine receptors emzimbeni. Iyaziwa ngokuthi i-non-ergot dopamine agonist. I-dopamine ingenye yama-neurotransmitters, noma izithunywa zamakhemikhali, ngaphakathi kwamangqamuzana angamazinyo ebuchosheni nasesimisweni sezinzwa zomzimba. Njengoba okuthiwa i-dopamine agonist, i-Neupro ithuthukisa umsebenzi walawa maseli abalulekile.
Ubani Okungafanele Asebenzise I-Neupro Patch?
Kunezimo ezithile lapho ama-patches ka-Neupro kufanele asetshenziswe ngokuqapha noma cha. Akufanele isetshenziswe esimisweni se-psychosis. Kufanele isetshenziswe kuphela ngokuqapha uma uthola uketshezi kwi-sulfite. I-Neupro inekhono lokusebenzisana neminye imithi, ikakhulukazi leyo engase icindezele amazinga okuqonda.
Kufanele uxoxe ngokusetshenziswa kwawo kanye nokukwazi ukuxhumana neminye imithi yakho nodokotela wakho. Ukusetshenziswa kotshwala kufanele kugwenywe ngokusetshenziswa kwe-Neupro. Ukuqapha okuqhubekayo kuyadingeka ekubhekaneni nesifo senhliziyo kanye nezinye izinkinga zokulala ezandisa ingozi yokulala ngokweqile emini. Njengoba kungase kubangele ukuvuvukala ezinyaweni noma emilenzeni njengomphumela ohlangothini, i-Neupro akufanele isetshenziswe yilabo abangase babe engozini yokugcina amanzi. Ukuphepha kwe-Neupro ekukhulelwe nasekunceliseni akuziwa.
Yiziphi Imiphumela Ezingavamile Ezihlanganiswa Ne-Neupro Patch?
Njengazo zonke izidakamizwa, kukhona okungenzeka kube nemiphumela emibi kakhulu ngokusetshenziswa kwekhasi le-Neupro. Nakuba ungenakulindela ukuthi ube nemiphumela emibi kakhulu-futhi cishe ngeke uhlangabezane nanoma yikuphi-okunye okwejwayelekile okungahle kwenzeke ngokusebenzisa Neupro kufaka:
- Ukusabela kwesithombeni endaweni yesicelo se-patch (okuthinta u-37% ngonyaka ongu-1)
- Ukulala noma ukukhathala
- Ukuvuvukala (i-edema ye-Peripheral)
- Ukudabuka noma ukuhlanza
- Isisu esibuhlungu
- Ukulahlekelwa kwesifiso
- Isizungu
- Izinwele
- Ukuqwashisa noma ukuphazamiseka kokulala
- Ukuphunga
- Izinguquko ezibonakalayo
- Ukubomvu (i-Erythema)
- Ubuhlungu obuhlangene noma ama-muscle spasms
- Ukuqokwa
- Umfutho wegazi ophezulu (i-Hypertension)
- Amaphupho angavamile
- Ukutheleleka okuphezulu kokuphefumula (njengemvula evamile)
- Ukuziphatha okucindezelayo (njengokuthenga okungalawulwa noma ukugembula)
- Ingozi yesifo ivuselelwe noma i- augmentation (ethinta 13%)
Ekulingweni kweminyaka emihlanu yeziguli ezingu-295 ezisetshenziswa ngeNeupro, 57% ukwelashwa okuyeke. Kulesi sifundo, ama-30% ayeke ukusetshenziswa ngenxa yemiphumela emibi futhi abangu-11% bayeka ukusebenzisa le patch ngenxa yokungabi nzuzo. Uma ukhathazekile ngomphumela ongase ube nomphumela, kunconywa ukuba uxhumane nodokotela wakho odokotela ngokushesha.
Yini Engabangela Ukubhekana Okujulile Ne-Neupro Patch Use?
Ukusabela okujulile kumuthi kungase kwenzeke. Yize lezi zenzeke ngokungajwayelekile, ezinye zezenzo ezingathinta izinkinga zihlanganisa:
- Ukulala ngokungazelelwe iziqephu
- Lightheadedness noma ukuphelelwa amandla
- Ama-hallucinations
- I-Psychosis
- Izinguquko ezibonakalayo
- I-Fibrosis (ukuqina noma ukunqunywa kwezicubu) izinkinga ze-tic
- Ukuguqulwa kokubuyisela (ekufundeni kwesilwane)
- I-neuroleptic syndrome enonya (ekuhoxisweni ngokuzumayo)
Uma ukhathazekile nganoma yikuphi kwalokhu kusabela okujulile, cabangela ukuhlolwa okuphuthumayo futhi unqabe ukusebenzisa imithi ngaphansi kokuqondiswa udokotela.
Ulwazi Olwengeziwe Mayelana Neupro Sebenzisa: Izindleko, Ukubekwa, Nokuqapha
Ukuze ukwelashwa kwe-syndrome engenamilenze engapheli, amanani we-1 mg kuya ku-3 mg asetshenziselwa ukwelashwa. Ngokuvamile, i-dose ephansi iqalile futhi yanda kuphela njengoba kudingeka. Amanani kufanele akhuliswe emva kweviki elilodwa lokusetshenziswa. Uma imithi ivaliwe, amanani kufanele anciphise ngo-1 mg njalo ngelinye ilanga bese ema. Izindleko ziyahlukahluka ngokufaka umshwalense nemanani ekhemisi.
Isiqephu se-Neupro sifakwa esikhumbeni futhi isayithi lokubekwa kufanele lijikelezwe. Kufanele isetshenziswe kanye ngosuku ngosuku. Indawo ngayinye yesicelo kufanele isetshenziswe kanye namaviki amabili ukugwema ukuhlaselwa.
Kukhona abanye okufanele basebenzise i-Neupro ngokuqapha noma cha, njengoba kuchazwe ngenhla. Ukuphepha kwemithi ekukhulelwe nokuncelisa akusiyo kahle. Kubalulekile ukuqapha ukucindezeleka kwegazi lapho uqala noma ukwandisa umthamo wemithi ukugwema ukuphelelwa amandla. Ukuhlolwa kwesikhumba njalo kufanele kwenziwe ukuze kubone noma yikuphi ukuphendula. Njengoba ukusekelwa kwe-patch kuqukethe i-aluminium, kufanele kususwe ngezinqubo zokuphefumula kanye nangesikhathi se- MRI ukugwema ukushisa. Njengoba kuchazwe ngenhla, imithi kufanele ifakwe uma iphelelwa ukugwema imiphumela emibi ekuhoxisweni okuphuthumayo.
Uma unenkinga ekusetshenzisweni kwe-Neupro, kufanele uxhumane eduze nomhlinzeki wakho wezempilo oyilungiselelo noma isazi sokulala esiqinisekisiwe ebhodini .
> Imithombo:
> "Neupro." I-Epocrates Rx Pro. Inguqulo 5.1.2, 2013. Epocrates, Inc. San Mateo, California.
> Oertel W, et al . "Ukuphepha Kwesikhathi Eside Nokusebenza Kwe-R otigotine Transdermal Patch ye-Moderate-to-Serious Idiopathic Restless Legs Syndrome: Isifundo Sokukhuliswa Kwetayiteli Lokuvula Lokungu-5." I-Lancet Neurol 2011; 10: 710-720.