Ukuguqulwa kwesifo somdlavuza webele, ukuhlolwa kanye nokwelapha
I-tumor grade yiyodwa yezinto eziningi ezizovela embikweni wakho wezokwelapha. Le datha iyasiza udokotela wakho anqume ngemithi ephumelelayo kakhulu yomphumela omuhle kakhulu. Umdlavuza wesibeletho uhanjiswa usebenzisa isimiso se-Bloom-Richardson. Nansi okudingeka ukwazi.
Izinto Ezithinta Ukwelashwa Nemiphumela
Uma ngabe unesifo sokubeletha sebele futhi uthola ukuthi unesifo somdlavuza webele , uzodinga ukwazi ukuthi iziphi izindlela zokwelashwa ezikuhle kakhulu kuwe, nokuthi yikuphi okuzokwenza ube khona. Isibikezelo indlela yodokotela wakho yokusho umphumela wakho omuhle emva kokuqeda ukwelashwa. Kunezici eziningi ezibhekwayo ekwenzeni izinqumo eziqondile zokuthola ukwelapha nokuphathwa kokwelapha - uhlobo lomdlavuza wesifuba , ubukhulu besisu , isigaba , isimo se-recemor receptor , ukubandakanyeka kwe-lymph node , kanye nebanga lesisu.
Uhlelo lwe-Bloom-Richardson Yokubamba
Kunezinhlelo eziningi ezihlukene zokufaka umdlavuza. Uhlelo lweBloom-Richardson lisetshenziselwa ukufaka umdlavuza wesifuba, futhi lunesilinganiso se-1 - 3. I-pathologist izothatha isampula yezicubu ezivela ku-tumor yakho, futhi uyihlole ngaphansi kwe-microscope. Amangqamuzana amathumba afana namaseli avamile anikwa ibanga eliphansi, kuyilapho labo ababukeka bengavamile kunikezwa ibanga eliphezulu. Izicubu eziphezulu kakhulu zikhula ngokushesha, zisakazeka (imetastatic) , futhi zinobudlova. Ukwazi ibanga lakho le-tumor kusiza udokotela wakho anqume ukuthi yiziphi izindlela zokwelapha okungcono kakhulu kuwe.
Inqubo Yokubamba Ukuthutha
I-pathologist ibuka amaseli we-tumor futhi ihlola izici ezintathu ezincane:
- ukwakheka kwe-tumor tile (amaphesenti omdlavuza owakhiwa izakhiwo ezibulalayo)
- umsebenzi we-tumor mitotic (isilinganiso sesigaba se-cell)
- ibanga le nyukliya (usayizi weseli nokufana)
Isici ngasinye sitholwe ngesilinganiso se-1 - 3.
Izilinganiso zesici seselula
Isifo sezokwelapha sizokwazisa ukubaluleka kwesici ngasinye samaseli, esekelwe emsebenzini wawo. Yile ndlela amazinga angase aqondwe ngayo:
Isici sesici 1: Ukunciphisa izinga lokukhula kwamaseli
Isici sesici 2: Izinga eliphezulu lokukhula kweseli
Isici sesici 3: Izinga lokukhula kwamaseli okusheshayo
Izibalo ezifakiwe zihlanganisa amaBanga amathathu
Amaphuzu azo zonke izici ezintathu afakwe ndawonye inani eliphakathi kuka-3 no-9.
Chofoza etafuleni ngakwesobunxele ukuze ukwandise bese ubona ukuthi Isici Sinikeza Ukuqhathaniswa Nokuhlukunyezwa kwamaBanga. Ibanga 1 liyinto encane kakhulu, kanti iBanga lesi-3 yilona uhlobo lwesifo esibi kakhulu.
Ukwenza iMathe
Nasi isibonelo. Uma isisu sesinezici zesici:
Ukwakhiwa kwe-Tubule: 1
Umsebenzi weMitotic: 2
Ibanga le nyukliya: 2
Sengeza u-1 + 2 + 2 = 5, okunikezwa i- Grade 1 , uhlobo oluthile olushubile, oluthile oluhlukumezayo.
Izicubu ezinikezwa izinga eliphezulu futhi eziqukethe amaseli afile (necrosis) zingase ziphinde zibuyele emuva kokwelashwa. Amathumba aphezulu aphezulu azophathwa kabi kakhulu kunama-tumor aphansi.
> Imithombo:
> National Cancer Institute. I-Tumor Grade: Imibuzo nezimpendulo. Kubuyekezwe: 05/19/2004.
> Registry Cancer Registry. Umqulu I: Amazinga Okudatha Ne Data Data. I-Bloom-Richardson Ibanga le-Cancer Breast Kubuyekezwa ngoMeyi 2007.