I-rheumatoid Arthritis nokufa
Ngolunye usuku, ngezwa othile ethi, "Yebo, isifo samathambo asinakubulala." Ngingafuni ukungena engxoxweni eyinde, ehilelekile ngaleso sikhathi, ngathungatha ngokungenakuqondakala, "Empeleni, kunzima kakhulu kunalokho."
I-arthritis ye-rheumatoid ngokuvamile ayibhekwa njengesifo esibulalayo noma esibulalayo. Eqinisweni, kuvame ukubizwa ngokuthi yisifo esingapheli, okusho ukuthi uzoba nakho isikhathi eside sempilo yakho.
Lesi sifo sihlobene nengozi ephezulu yezinkinga ezingase zibulale, noma kunjalo.
I-arthritis ye-rheumatoid ihlotshaniswa nokuphila okunciphise isikhathi eside , ikakhulukazi ngenxa yezinkinga ezingase zikhule. Kulinganiselwa ukuthi isikhathi sokuphila singadliwa iminyaka engaba ngu-10 kubantu abane-arthritis ye-rheumatoid. Ukuvuvukala kwesimiso okuhlobene nesifo samathambo esifubeni kucatshangelwa ukuthi kubangele ukungahambi kahle ngokuphila okuncishisiwe, kanye nokudlala indima ekwandiseni ingozi yokutheleleka okukhulu, isifo senhliziyo, isifo sokuqina kwesifo sofuba, kanye nesifo somzimba-noma yikuphi okungaholela ekufeni kwangaphambi kwesikhathi.
Izifo Zezinhliziyo
Isixhumanisi phakathi kwe- arthritis ye-rheumatoid nokukhula kwesifo senhliziyo isifunde kahle futhi siyaqhubeka nokugxila ocwaningweni. Isifo senhliziyo siyisifo esiyinhloko sokufa phakathi kwegazi elinesifo sofuba. Cishe amaphesenti angu-40 abantu abafa e-rheumatoid arthritis abhekene nemicimbi yezinhliziyo.
Abantu abane-arthritis ye-rheumatoid banezinkinga eziphindwe kabili zokuhlaselwa yinhliziyo noma isifo sokushaya isifo uma kuqhathaniswa nabantu abangenawo isifo samathambo. Ingozi ikhula cishe cishe kathathu kubantu abaye banesifo samathambo iminyaka eyishumi noma ngaphezulu.
Okuthakazelisayo ukuthi, izifo ezivamile ezingozini zesifo senhliziyo azichazi isithombe sonke kubantu abane-arthritis ye-rheumatoid.
Kunezinye izindlela ze-pathogenic (ezibangelwa isifo) ezidlala, ikakhulukazi ezihlobene nokuvuvukala kwesistimu. Izinqubo ezinjalo zingabandakanya i-pro-oxidative dyslipidemia (amazinga angavamile amafutha egazini), ukumelana kwe-insulin, ukufakwa kwesimo segazi, ama-highcytosteine egazini, nemisebenzi ethile yemzimba, njenge-T-cell activation.
Kodwa-ke ezinye iziguli eziphazamisayo-izifo zesifo samathambo asikwazi ukubika izinhlungu zesifuba kunabanye abangenalo i-rheumatoid arthritis. Bajwayele ukuzwa ukungenwa kwe-myocardial infarction (ukushaya kwenhliziyo) noma ukufa okungazelelwe komzimba.
I-Metabolic Syndrome
I-metabolic syndrome , iqoqo lezinkinga zendabuko yemvelo, kuhlanganise nokucindezeleka, ukukhuluphala ngokweqile, ukubekezelelana kwe-glucose, kanye ne-dyslipidemia ivame kakhulu kubantu abane-arthritis ye-rheumatoid. Amakhamera aphezulu okuvuvukala kanye nokusetshenziswa kwe- glucocorticoids kubhekwa njengama-predictors of presence of syndrome ye-metabolic kulabo abane-arthritis ye-rheumatoid.
Ucwaningo olulodwa, olwanyatheliswa kuyi- Journal of Rheumatology ngoJanuwari 2011 lwaluhlolisisa ukuthi iziguli zesifo se-rheumatoid ezingenayo izibonakaliso ezicacile zezifo zenhliziyo zinezifo eziphakeme kakhulu zesifo se-metabolic syndrome.
Isiphetho sasiwukuthi abantu abane-arthritis ye-rheumatoid babenezinga eliphakeme le-syndrome ye-metabolic.
I-aestrosclerosis
Abantu abane-arthritis ye-rheumatoid banesisindo esiphezulu se-atherosclerosis kunalabo abangenayo i-arthritis ye-rheumatoid. I-arthritis ne-rheumatoid arthritis ingabelana ngezindlela ezimbalwa ze-pathogenic, futhi ukuvuvukala kwesistimu kungenzeka phakathi kwabo. Kungase kube nezinqubo zofuzo ezihilelekile. Izinqubo ezizimele ngokuzenzakalelayo zidlala indima kokubili kwesifo se-rheumatoid ne-atherosclerosis, futhi.
Izifo Ezimbi
Iziguli ze-arthritis ze-rheumatoid ziye zaboniswa ukuthi zinengozi enkulu yokutheleleka.
Ngokwesinye isifundo, kwanyatheliswa kuyi- Arthritis ne-Rheumatism , ngo-September 2002, ehlola ukubikezela kokutheleleka kwesifo samathambo, ukukhula kweminyaka, ukubonakaliswa okungeziweko kwesifo samathambo (isib., Izici ngaphandle kokubandakanyeka kokuhlanganyela), ukungahambisani nokusetshenziswa i-corticosteroids yayiyizibikezelo eziqinile zokutheleleka. Ngokuthakazelisayo, ngokusho komphumela wokucwaninga ku-May 2013 Journal of Rheumatology izinga lokutheleleka okuthelelekile ezigulini ze-rheumatoid arthritis kuye kwehla eminyakeni embalwa edlule.
Ukuguqulwa kwamathumbu
Esinye isizathu esibangela ukufa kufana nesifo se-rheumatoid isifo somzimba esiswini . Kuyinto engavamile, kodwa isenzakalo esibi kakhulu uma kwenzeka. Abantu abaphathwa nge-glucocorticoids, izidakamizwa ezingezona ukuvuvukala ( non-steroidal anti-inflammatory drugs ) (NSAIDS) noma abanomlando we- diverticulitis basengozini enkulu yokuthola izinkinga zamathunjini.
> Imithombo:
> Dhawan SS et al. Isifo samathambo nesifo senhliziyo. Imibiko yamanje ye-Atheroclerosis. 2008, 10 (2): 128-33.
> Rosom S et. al. Izinkinga ze-BMC ze-Musculoskeletal: I-Metabolic Syndrome e-Rheumatoid Arthritis: Ucwaningo lokulawula icala. Ngo-Ephreli 26, 2013.
> Crowson CS et al. Ukwanda kwe-syndrome ye-metabolic ehlotshaniswa ne-arthritis ye-rheumatoid ezigulini ezingenalo isifo senhliziyo esisemtholampilo. Journal of Rheumatology January 2011.
> Cavagna l et al. I-arthritis ne-rheumatoid arthritis: okungaphezu kokuhlangana okulula. Abahleli be-Inflammation. 2012; 2012: 147354. Ngo-Septhemba 13, 2012.
> NguMhuircheartaigh et al. Amathrendi ezifo ezibi kakhulu e-rheumatoid arthritis. Journal of Rheumatology. May 2013.
> UDoran MF et al. Izibikezelo zokutheleleka kwi-rheumatoid arthritis. I-arthritis ne-Rheumatism. September 2002.
> Curtis JR et al. Isibalo sezifo zamathumbu phakathi kweziguli ze-rheumatoid arthritis. I-arthritis ne-Rheumatism. February 2011.