Ukwelapha Izinkinga Zase-Urinary Ekusebenziseni Kwesilisa Ngokobulili
Kunezidakamizwa eziningi ezisetshenziselwa urology , okhethekile kwezokwelapha okubhekene nezifo zesigqila samadoda nabesilisa kanye nesistimu yokuzala yesilisa. Lezi zidakamizwa zingahle ziphulwe ngokwemisebenzi yazo yesenzo kanye nomsebenzi wezinto eziphilayo ezibhekiswe kuzo.
Amakilasi ajwayelekile kakhulu okushiwo izidakamizwa ku-urology afaka:
- I-Alpha blockers esebenza ngokusihlisa imisipha entanyeni yentambo ukuze kuthuthuke ukugeleza kwamanzi
- I-5-alpha inhibitors evimbela ukukhiqizwa kwe-hormone ethile yesilisa ehambisana nokukhulisa i-prostate
- I-Anticholinergics eyancipha ukunciphisa isisindo futhi ukwandisa ikhanda lesikhumba kubantu abanesisindo esingenamandla
Izidakamizwa zingasetshenziselwa ngokwazo noma ngezokwelapha ezihlangene. Ezinye izinkampani zokwelapha ziye zadala nezidakamizwa ezimbili-inye-nye njengeDuodart ehlanganisa i-blocker ye-alpha ne-5-alpha inhibitor.
I-Alpha Blockers
I-Alpha blockers, ebizwa ngokuthi i-alpha-adrenergic antagonist, isetshenziselwa urology ukuphatha ukwanda okungeyona umdlavuza we-prostate gland (eyaziwa nge- benign prostatic hyperplasia, noma i-BPH ). Benza kanjalo ngokuvimbela i-hormone i-norepinephrin ekunqandeni imithwalo ethile ebushelelezi nemithambo yegazi. Ngokwenza kanjalo, lesi sidakamizwa singathuthukisa ukugeleza kwamanzi kumadoda amadala anezinkinga ze-prostate.
Ama-Alpha blockers okwamanje avunyelwe ukwelashwa kwe-BPH afaka:
- I-Cardura noma i-Cardura XL (doxazosin)
- I-Flomax (i-tamsulosin)
- I-Hydrin (i-terazosin)
- Uroxatral (alfuzosin)
Amanye ama-blockers e-alpha atholakalayo ekufomeni okwesikhashana kanye nesikhathi eside. Izidakamizwa ezinomsebenzi zisebenza ngokushesha, kodwa imiphumela yazo iphela amahora ambalwa. Izinguqulo ezinde isikhathi eside zingathatha isikhathi eside ukusebenza, kodwa imiphumela yazo ihlala isikhathi eside. Ukuzikhethela kokubunjwa kuxhomeke kakhulu ekuqotheni kwe-BPH.
Ngokusobala, i-alpha blockers ingabangela ugozi, ikhanda, i-postural hypotension (umfutho wegazi ophansi uma uma), noma ukubuyisela emuva ukujula (isimo lapho isithombo senziwa khona esikhwameni).
5-Alpha Inhibitors
I-5-alpha inhibitors, eyaziwa nangokuthi i-5-alpha reductase inhibitors, isebenza ngokuvimbela ukuguqulwa kwe-testosterone ku-dihydrotestosterone, i-hormone ehambisana no-BPH no-baldness wesilisa. Ama-inhibitors ama-5 anqunyelwe ukwelapha okungapheli kwe-BPH futhi angathatha izinyanga eziyisithupha ngaphambi kokuba imiphumela izwe ngokugcwele.
I-5-alpha inhibitors okwamanje evunyelwe ukwelashwa kwe-BPH yilezi:
- I-Avodart (i-dutasteride)
- Propecia noma i-Proscar (i-low-and-high-dose finasteride, ngokulandelana)
Njengesigaba samachidakamizwa, ama-5-alpha inhibitors angabangela ukulahlekelwa kwe-libido, ukungabi namandla, noma ukubuyisela kabusha i-ejaculation.
Anticholinergics
Izidakamizwa ze-anticholinergic zivimbela isenzo se-neurotransmitter yamakhemikhali, esaziwa ngokuthi i-acetylcholine, esithumela izibonakaliso ebuchosheni obangela izinqamuzana ezingavamile zesisu. Ngokwenza kanjalo, izidakamizwa zinganciphisa izimpawu zesisindo esingenakuthola lapho abantu bazizwa sengathi badinga ukuchama ngisho nalapho isilonda singagcwele.
Phakathi kwama-anticholinergics okwamanje avunyelwe ukwelashwa kwesinye isinye sikhambi:
- I-Detrol (tolterodine)
- I-Enablex (darifenacin)
- Oxytrol noma Ditropan XL (oxybutynin)
- I-Regurin ne-Sanctura (i-trospium chloride)
- I-Toviaz (i-fesoterodine)
- I-Vesicare (i-solifenacin)
I-Anticholinergics ingabangela umlomo owomile, ukuqothulwa, umbono obonakalayo, nokushaya kwenhliziyo okusheshayo (tachycardia).
Ezinye izidakamizwa ezisetshenziswa ku-Urology
Njengoba okukhethekile kuhlanganisa kokubili ukwelashwa kokuvuthwa kwamadoda kanye namadoda, izazi ze-urologists zithembela ku-armory yemithi yokwelapha ukuze ziphathe izimo ezinjenge- cancer yomzimba , izifo zokungcolisa umchamo (UTIs), ukungasebenzi kwe-erectile (ED) , i-hypogonadism (ukukhiqizwa okuphansi kwe-testosterone) , nesifo se-Peyronie (isimo esiboniswa ukulungiswa okubukhali, okubuhlungu).
Ukuze uthole urologist ofanelekayo eduze kwakho, thintana nenkampani yakho yomshuwalense ohlwini lwabahlinzeki abavunyiwe noma ubuze udokotela wakho wokunakekela oyinhloko ngokudluliselwa. Ungabheka iziqinisekiso ze-urologist kanye nesitifiketi ngokusebenzisa iBhodi yaseMelika yezokwelapha (ABMS) kanye namawebhusayithi ahlukahlukene wokubukeza udokotela .
> Umthombo:
> Hanno, P .; I-Guzzo, T .; Malkowicz, P. et al. (2014) I- Penn Clinical Manual of Urology: I-Expert Online (Okwesibili Ed.) Philadelphia, Pennsylvania: Saunders. I-ISBN-13: 978-1455753.