I-Picamilon iyisithako sokudla esenziwe ngokuhlanganiswa kwe-niacin (eyaziwa nangokuthi i-vitamin B3) ne- gamma-aminobutyric acid (i-GABA) . Ngezinye izikhathi okubizwa ngokuthi i-nicotinoyl-GABA, i-picamilon ithengiswa njengesidakamizwa somuthi eRussia.
I-Niacin yaziwa ngokukhuthaza ukukhuliswa kwemithambo yegazi, kuyilapho i-gamma-aminobutyric acid idlala indima ebalulekile ekulawuleni umsebenzi wesistimu wezinzwa.
I-amino acid etholakala ngokwemvelo emzimbeni wakho, i-GABA isebenza njenge-neurotransmitter (uhlobo lwekhemikhali elibhekene nokwenza ulwazi kusuka kwesinye iseli kuya kwesinye). Ucwaningo lubonisa ukuthi abantu abanezinkinga ezithile zempilo yengqondo (njengokucindezeleka okukhulu nokukhathazeka) kungenzeka kube namathuba amaningi okuba namazinga aphansi e-GABA.
Ukusetshenziswa
I-Picamilon ivame ukubizwa ngokuthi "izidakamizwa ezihlakaniphile," isigaba semithi esetshenziselwa imithi yokwelapha ukuthuthukisa ukusebenza kobuchopho. Ngaphezu kwalokho, kusho picamilon ukusiza ukuphatha lezi zimo ezilandelayo:
- Ukukhathazeka (kubandakanya ukukhathazeka komphakathi)
- Ukucindezeleka
- Umfutho wegazi ophezulu
- I-Migraine
Abanye abaxhasi bezokwelapha abathile bathi i-picamilon ingasiza ekuvuseleleni imemori, ukuthuthukisa isimo sengqondo, nokuvikela isifo so-Alzheimer.
Izinzuzo
Kuze kube manje, ezimbalwa izifundo zesayensi ziye zahlola imiphumela yezempilo ye-picamilon. Kodwa-ke, olunye ucwaningo lokuqala lubonisa ukuthi i-picamilon inganikeza izinzuzo ezithile.
Isibonelo, isifundo esisekelwe esigodini esakhishwa yi-Kiev's Institute of Biochemistry ngo-1998 sinqume ukuthi i-picamilon ibonisa isithembiso sokwelashwa nokuvinjelwa kwesifo sofuba sikashukela (isimo esibonakaliswe umonakalo wezinzwa obangelwa ukuphakama kwesifo sikashukela- ehambisana namazinga ehukela egazini).
Kodwa-ke, okwamanje kuntuleka kwemiphumela yokuhlolwa kwe-clinic yokuhlolwa kwe-picamilon ngokumelene nesifo senhliziyo yesifo sikashukela.
Ngaphezu kwalokho, isifundo se-2010 eshicilelwe encwadini yeRussia, i- Experimental and Clinical Pharmacology ithole ukuthi i-picamilon ingasiza ukuvikela ngokumelene ne-hypokinesia. Ekuhlolweni kwamagundane, abalobi besifundo bathola ukuthi umjovo we-picamilon usize ukubuyisela inombolo yezilwane ye-GABA receptors (isigaba sama-molecule esabela ku-GABA).
Isimo esimakwe ngokunyakaza komzimba, i-hypokinesia ngezinye izikhathi ihlotshaniswa nesifo sikaParkinson nezinye izinkinga zezinzwa.
Amapulangwe
Ngenxa yokuntuleka kocwaningo, kuncane okuyaziwa ngokuphepha kokusetshenziswa okuvamile kwe-picamilon. Kodwa-ke, kunokukhathazeka okuthile ukuthi i-picamilon ingabangela imithwalo yemiphumela emibi, efana nokukhanda ngamakhanda, ukuxubha, nesicashu. I-Picamilon ingaxhumana nemithi ethile, njenge-benzodiazepines.
Kubalulekile ukukhumbula ukuthi ama-supplements awazange ahlolwe ukuphepha kanye nezondlo zokudla ngokuvamile azihambisani nomthetho. Kwezinye izimo, umkhiqizo ungase ulethe ukulinganisa okungafani nesilinganiso esicacisiwe semifino ngayinye. Kwezinye izimo, umkhiqizo ungangcoliswa nezinye izinto ezifana nezensimbi. Futhi, ukuphepha kwezidakamizwa kwabesifazane abakhulelwe, omama abahlengikazi, izingane, nalabo abanezimo zezokwelapha noma abaphuza imishanguzo azange zisungulwe.
Ezinye izindlela
Uma ufuna ukuthuthukisa ukusebenza kobuchopho, iningi lemithi yokwelapha ingase isebenze njengenye indlela eya ku-picamilon. Isibonelo, ama-fatty acids ama-omega-3 atholakale ukuthuthukisa umsebenzi wokuqonda, ukulondoloza inkumbulo, nokuvikela ukucindezeleka nesifo se-Alzheimer. Kutholakale ngokwemvelo ekudleni okufana namafutha e-flaxse kanye nezinhlanzi ezinamafutha (kuhlanganise i-saumon, i-sardine, i-tuna, i-mackerel, ne-herring), i-omega-3 fatty acids nayo ithengiswa ngefomu lokufaka isicelo.
Kukhona nobufakazi bokuthi ezinye izindlela zokwelapha ezingase zenzeke zingasiza ekwandiseni amazinga e-GABA ebuchosheni. Isibonelo, ucwaningo lokuqala luveza ukuthi amakhambi afana neva ne- valerian angakhuphula amazinga we-GABA ngokugqugquzela ukukhiqizwa kwe-GABA noma ngokunciphisa ukuhlukana komzimba we-GABA. Ngaphezu kwalokho, ucwaningo oluthile lubonisa ukuthi ukwenza i-yoga kungasiza ukwandisa amazinga e-GABA akho, futhi futhi, ngcono isimo sengqondo nokunciphisa ukukhathazeka.
Lapho Uzoyithola khona
Etholakala kakhulu ukuthengwa ku-intanethi, i-picamilon ithengiswa kwezinye izindawo zokuthengisa izidakamizwa.
Izwi elivela
Ngenxa yokucwaninga okulinganiselwe, kusheshe kakhulu ukutusa i-picamilon njengokwelashwa kwanoma yisiphi isimo.
Kumele kuqashelwe ukuthi ukuphatha isimo nge picamilon nokugwema noma ukubambezela ukunakekelwa okujwayelekile kungaba nemiphumela emibi kakhulu. Uma ucabangela ukusebenzisa i-picamilon ngesimo (njengesifo esiphakeme segazi noma isifo se-Parkinson), thintana nodokotela wakho ngaphambi kokuthatha lesi sidakamizwa, njengoba kungase kungalungile noma kuphephile kubantu abanezimo ezithile, njengomdlavuza.
Imithombo
Kuchmerovskaia TM, Parkhomets PK, Donchenko GV, Obrosova IG, Klimenko AP, Kuchmerovskiĭ NA, Pakirbaeva LV, Efimov AS. "Ukulungiswa kwe-neuropathies yesifo sikashukela esebenzisa i-aldose reductase inhibitors ne-pikamilon." I-Vopr Med Khim. 1998-Nov-Dec; 44 (6): 559-64.
I-Apipian VP, i-Balian LS, i-Zakarian NA. "Imiphumela ye-nootropics ekushintsheni okulinganiselwe ku-rat ye-cerebral cortex ye-GABA (A) ye-receptor eyinkimbinkimbi ngaphansi kwezimo ze-hypokinesia zokuhlola." Eksp Klin Farmakol. 2010 Jul; 73 (7): 13-5.
Ukuziphendulela: Ulwazi oluqukethwe kule sayithi luhloswe ngezinjongo zemfundo kuphela futhi aluthathi iseluleko, ukuxilongwa noma ukwelashwa ngudokotela olayisensi. Akuhloselwe ukumboza zonke izinyathelo zokuqapha, ukusebenzisana kwezidakamizwa, izimo noma imiphumela emibi. Kufanele ufune ukunakekelwa okusheshayo kwezokwelapha kunoma yiziphi izinkinga zezempilo bese uthintana nodokotela wakho ngaphambi kokusebenzisa enye imithi noma wenze ushintsho ohlelweni lwakho.