Imithombo, Ukusetshenziswa, Nezinzuzo Zokuba Khona
I-Strontium iyinhlangano yamakhemikhali kuthiwa inikeza izinzuzo eziningi zezempilo. Ngokwezici ezifana ne-calcium, i-strontium ivame ukutholakala nemithi ehlukile njengendlela yokwelapha ngokwemvelo yokwelashwa kwe- osteoporosis .
Imithombo
Kutholakala ngefomu lokuxhaswa, i-strontium itholakala emanzini olwandle (futhi, futhi, ezindaweni zokudla zasolwandle nemifino yasolwandle). I-strontium ingatholakala nangokolweni kakolweni, imifino ehlathini, ubisi lonke, inyama, nezinkukhu.
Izinzuzo ezingenzeka
1) I-osteoporosis
Ekucwaningweni kwelabhuthrikhi, ososayensi bathole ukuthi i-strontium ranelate (uhlobo lwe-strontium ebhalisiwe njengesidakamizwa somuthi emazweni amaningi) lingasiza ekwandiseni ukwakhiwa kwethambo ngokukhuthaza ukukhula kwama-osteoblasts (uhlobo lwe-cell-forming cell).
Ngaphezu kwalokho, ucwaningo lwama-laboratory lubonisa ukuthi i-strontium ranelate ingasiza ekuvikeleni ekuhlukunyekeni kwethambo (inqubo eyaziwa ngokuthi "ukubuyisela amathambo"). Njengoba i-bone resorption idlala indima ebalulekile ekusungulweni kwe-osteoporosis, kucatshangwa ukuthi ukuvimbela ukuguqulwa kwamathambo ngokusetshenziswa kwe-strontium ranelate kungasiza ukunciphisa ingozi ye-osteoporosis kanye / noma usizo ekwelapheni kwe-osteoporosis.
Kuze kube manje, izilingo eziningi zokwelashwa ekusetshenzisweni kwe-strontium zixilisa ukwelashwa nokuvimbela ukugaya i-osteoporosis zigxile kubesifazane besimo se-postmenopausal. Ngenxa yokuthi ukwehla kokuphathelene nokunqamuka kokunqamuka kwamantombazane emazingeni e-estrogen kuhlobene kakhulu nokwanda kwethambo, ama-postmenopausal abesifazane abhekana nengozi yokugula i-osteoporosis.
Ukubuyekezwa kocwaningo olwenziwe ngo-2006 olwanyatheliswa ku- Cochrane Database of Reviews Systematic , ososayensi babheka idatha kusuka ekuvivinyweni kwemitholampilo (okungenani ngonyaka owodwa) ukuthi kuqhathaniswa ne-strontium eqhubekela phambili endaweni ye-placebo emiphumeleni yayo empilweni yamathambo kuma-postmenopausal abesifazane. Ukuhlaziya ukufundwa okuvela ezifundweni ezine ezihlangabezane nenqubo yokubuyekeza, ososayensi bathola ukuthi i-strontium ranelate ibonakala ukunciphisa ukuhlukana kweziguli ze-postmenopausal osteoporosis futhi kwandise isibalo samaminerali esitokisini kuma-postmenopausal abesifazane abane-osteoporosis noma abangenayo i-osteoporosis.
Ukuqaphela ukuthi ukusetshenziswa kwe-strontium ranelate kungabangela isifo sohudo, abalobi bokubuyekeza bacela ucwaningo olwengeziwe emiphumeleni engaba khona ye-strontium ranelate.
2) i-osteoarthritis
Kunobunye ubufakazi bokuthi i-strontium ingabasiza abantu abane- osteoarthritis . Isibonelo, isifundo se-2011 eshicilelwe encwadini yeCommmacteric sithole ukuthi i-strontium ranelate ingasiza ekunciphiseni ukuqhubeka kwe-osteoarthritis.
Lesi sifundo sasihlanganisa nabesifazane abangu-2,617 abaxoshwa ngemuva kwe-postmenopausal abane-osteoporosis (abanye babo babenomlando we-osteoarthritis). Izinyanga ezingu-36, amalungu okutadisha athatha noma yi-strontium ranelate noma i-placebo. Ekuhloliseni kwabo ukufundwa kokufundwa, abacwaningi baphetha ngokuthi i-strontium ranelate yasiza ukuvikela ukuhlukana kwe-cartilage (isici esibalulekile se-osteoarthritis).
3) Igciwane
Ngesinye isikhathi i-Strontium ifakwe njengokwelashwa kwemvelo ngenxa yobuhlungu be-bone obuhlobene nomdlavuza. Kodwa-ke, ngo-2011 ukubuyekezwa kocwaningo okushicilelwe ku- Database Cochrane Yokuhlola Okuhlelekile , abacwaningi bayaqaphela ukuthi okwamanje kunesibalo sobufakazi besayensi ukusekela ukuphumelela kwe-strontium njengokwelashwa ubuhlungu be-bone.
Amapulangwe
I-Strontium ngokuvamile ibhekwa njengokuphephile kubantu abaningi uma idliwe ngamanani ngokuvamile etholakala ekudleni okungenakuhlanjululwa. Kodwa-ke, ukusetshenziswa kwe-strontium supplements kungase kube yingozi kubantu abathile, kuhlanganise nabantu abanenkinga yegazi nabantu abasebenzisa imithi ethile (njenge-nifedipine, isidakamizwa esisetshenziselwa ukuphatha ukucindezeleka kwegazi nokulawula i- angina ).
Ngakho-ke, kubalulekile ukufuna iseluleko sezokwelapha uma ucabangela ukusebenzisa izithako ze-strontium.
Khumbula ukuthi ama-supplements awazange ahlolwe ukuphepha kanye nezindleko zokudla ngokuyinhloko ezingavunyelwe ngokomthetho. Kwezinye izimo, umkhiqizo ungase ulethe ukulinganisa okungafani nesilinganiso esicacisiwe semifino ngayinye. Kwezinye izimo, umkhiqizo ungangcoliswa nezinye izinto ezifana nezensimbi. Futhi, ukuphepha kwezidakamizwa kwabesifazane abakhulelwe, omama abahlengikazi, izingane, nalabo abanezimo zezokwelapha noma abaphuza imishanguzo azange zisungulwe. Ungathola amathiphu engeziwe okusebenzisa izithako lapha .
Ngaphambi kokusebenzisa iStrontium for Health
Nakuba kunobunye ubufakazi bokuthi i-strontium inganikeza izinzuzo ezithile zezempilo, kubalulekile ukubonisana nodokotela wakho ngaphambi kokusebenzisa i-strontium ukuphatha isimo. Ukuzibulala ngokweqile, i-osteoarthritis, noma yimuphi omunye isimo nge-strontium nokugwema noma ukubambezela ukunakekelwa okujwayelekile kungaba nemiphumela emibi.
Imithombo:
U-Alexandersen P, uKarsdal MA, Byrjalsen I, Christianen C. "I-Strontium ithonya elikhulu emadodeni ase-postmenopausal ahlukene ngamazinga e-osteoarthritis." I-Climacteric. 2011, 14 (2): 236-43.
U-O'Donnell S, uCranney A, Wells GA, Adachi JD, uReginster JY. "I-Strontium ixosha ukuvimbela nokwelapha i-postmenopausal osteoporosis." Cochrane Database Syst Rev. 2006 Okthoba 18; (4): CD005326.
I-Roqué I Figuls M, uMartinez-Zapata MJ, Scott-Brown M, u-Alonso-Coello P. "Ama-radioisotopes for ubuhlungu be-bone metastatic." I-Cochrane Database Syst Rev. 2011 Jul 6; (7): CD003347.
Reginster JY. "I-Strontium ixoshwa ekuphefumuleni kwe-osteoporosis." I-Curr Pharm Des. 2002; 8 (21): 1907-16.
Ukuziphendulela: Ulwazi oluqukethwe kule sayithi luhloswe ngezinjongo zemfundo kuphela futhi aluthathi iseluleko, ukuxilongwa noma ukwelashwa ngudokotela olayisensi. Akuhloselwe ukumboza zonke izinyathelo zokuqapha, ukusebenzisana kwezidakamizwa, izimo noma imiphumela emibi. Kufanele ufune ukunakekelwa okusheshayo kwezokwelapha kunoma yiziphi izinkinga zezempilo bese uthintana nodokotela wakho ngaphambi kokusebenzisa enye imithi noma wenze ushintsho ohlelweni lwakho.