Yini Okufanele Ngiyizi Ngayo?
I-Aniracetam wuhlobo lwe-nootropic, isigaba semithi esetshenziswa ukuthuthukisa ukusebenza kobuchopho. Nakuba i-aniracetam iyatholakala njengemithi yesidakamizwa eYurophu, okwamanje ayinakulawulwa e-United States.
Ukusetshenziswa kwe-Aniracetam
Njengoba zibizwa ngokuthi izidakamizwa ezihlakaniphile, i-aniracetam isetshenziselwa imithi yokwelapha ukuze ikhulise imemori, ithuthukise ukuhlushwa, futhi ikhulise ukuphazamiseka kwengqondo.
Ngaphezu kwalokho, i-aniracetam ngezinye izikhathi isetshenziselwa lezi zimo ezilandelayo:
- Isifo se-Alzheimer's
- ukunakekelwa kwephutha lokungaboni kahle
- ukukhathazeka
- ukucindezeleka
- ukugula okuhambayo
- ukuphazamiseka kokulala
I-Aniracetam iphinde ibekwe njenge-agent anti-aging.
Izinzuzo ze-Aniracetam
Nakuba izilingo ezincane zemitholampilo ziye zahlolwa imiphumela yezempilo ye-aniracetam, izifundo eziningi zokuqala zibonisa ukuthi i-aniracetam inganikeza izinzuzo ezithile zezempilo.
Embikweni oshicilelwe encwadini ye- CNS Izidakamizwa Zezidakamizwa ngo-2002, isibonelo, abaphenyi bahlaziya ucwaningo olutholakalayo mayelana nokusetshenziswa kwe-aniracetam ekwelapheni izimpikiswano zesishukela se-central (CNS) nezifo. Ukubheka okufundwayo kwizifundo ezisekelwe ezilwaneni, abacwaningi bathola ukuthi i-aniracetam ibonisa isithembiso ekuphathweni kwezimo ezifana ne-posttraumatic disorder disorder, ukunakekelwa kokulahlekelwa ukucindezeleka kokugula, i-autism, nokuphazamiseka kokulala. Kodwa-ke, abalobi bombiko babika ukuthi okwamanje "akukho bufakazi obukholisayo" bokusebenza kwe-aniracetam ekwelapheni noma yimiphi yalezi zimo kubantu.
Nakhu ukubuka okunye okutholakele okuyisisekelo kusuka kwizifundo ezitholakalayo ku-aniracetam:
1) Ukukhathazeka
I-Aniracetam ingasiza ekwelapheni ukukhathazeka kokukhathazeka, ngokwe-2001 eyanyatheliswa kuyi- European Journal of Pharmacology . Ekuhlolweni kwamagundane, abacwaningi bathola ukuthi i-aniracetam ingasiza ekunciphiseni ukukhathazeka ngokuthinta ama-neurotransmitter amaningana (isigaba samakhemikhali ahilelekile ekuthwaleni imiyalezo esuka kumangqamuzana omzimba kuya kwamanye amaseli).
2) Ukucindezeleka
I-Aniracetam ingase ibe nemiphumela efana ne-anti-depressant-like, isifundo se-2001 esivela encwadini ethi Psychopharmacology sikhuthaza . Ekuvivinyweni kwamagundane, ososayensi bathole ukuthi i-aniracetam ingasiza ekuvuseleleni ukudluliswa kwe-dopamine (i-neurotransmitter evame ukutholakala emazingeni aphansi kubantu abanokucindezeleka).
3) Ukukhubazeka kwengqondo
Izifundo eziningana zokuqala zibonise ukuthi i-aniracetam ingaba yinzuzo ethile kubantu abanokukhubazeka kwengqondo. Isibonelo, isifundo se-2012 eshicilelwe ku- CNS Neuroscience & Therapeutics sathola ukuthi ukwelapha abantu asebekhulile nge-aniracetam unyaka kwaholela ekuthuthukiseni okuphawulekayo emsebenzini wokuzicabangela. Kubandakanya abantu abadala abangama-276 abanenkinga yokucabanga, isifundo sathola nokuthi i-aniracetam yayinemiphumela enenzuzo emzimbeni nasenhlalakahle yomzwelo.
Ngaphezu kwalokho, isifundo esisekelwe emagatsheni eshicilelwe ku- Psychiatry and Clinical Neurosciences ngo-2000 sathola ukuthi i-aniracetam ingasiza ekuphatheni ukuphazanyiswa kokulala okuhambisana nokuhlolelwa komqondo .
Amapulangwe
I-Aniracetam ingabangela imithwalo yemiphumela emibi, kufaka phakathi ukuleleka , ikhanda , ukukhathazeka, ubuhlungu , i-vertigo, i-nausea, nesifo sohudo .
Ngenxa yokuntuleka kocwaningo, kuncane okuyaziwa ngokuphepha kokusebenzisa i-aniracetam. Kubalulekile ukukhumbula ukuthi ama-supplements awazange ahlolwe ukuphepha kanye nezondlo zokudla ngokuvamile azihambisani nomthetho.
Kwezinye izimo, umkhiqizo ungase ulethe ukulinganisa okungafani nesilinganiso esicacisiwe semifino ngayinye. Kwezinye izimo, umkhiqizo ungangcoliswa nezinye izinto ezifana nezensimbi. Futhi, ukuphepha kwezidakamizwa kwabesifazane abakhulelwe, omama abahlengikazi, izingane, nalabo abanezimo zezokwelapha noma abaphuza imishanguzo azange zisungulwe. Ungathola amathiphu engeziwe okusebenzisa izithako lapha .
Lapho Uzoyithola khona
I-Aniracetam iyatholakala kakhulu ekuthengeni ku-intanethi.
Ukusebenzisa i-Aniracetam yezeMpilo
Ngenxa yokucwaninga okulinganiselwe, kusheshe kakhulu ukutusa i-aniracetam kunoma iyiphi injongo yezempilo. Kubalulekile ukuqaphela ukuthi ukuzitholela isimo esingapheli nge-aniracetam nokugwema noma ukubambezela ukunakekelwa okujwayelekile kungaba nemiphumela emibi.
Uma ucabangela ukusebenzisa i-aniracetam, qiniseka ukuthi uxhumana nodokotela wakho ngaphambi kokuyisebenzisa.
Imithombo
U-Kimura M, Okano S, Inoué S. "Imiphumela ye-aniracetam emaphethweni okulala okungafaneleki ekuguleni okwenziwe yi-rhythm." I-Psychiatry Clin Neurosci. 2000 Jun; 54 (3): 314-6.
I-Koliaki CC, i-Messini C, i-Tsolaki M. "Ukusebenza kahle kwe-aniracetam emtholampilo, njengokuthi i-monotherapy noma ihlangene ne-cholinesterase inhibitors, ezigulini ezinokukhubazeka kwengqondo: ukutadisha okuvulekayo." I-CNS Neurosci Ther. 2012, 18 (4): 302-12.
Li Y, Wang JJ, Cai JX. "I-Aniracetam ivuselela imiphumela yeprotheni ye-amyloid-beta noma iguga ekufakeni uketshezi lwe-membrane fluxum kanye ne-intracellular concentration concentratory in syaptosomes yamagundane." J Neural Transm. 2007; 114 (11): 1407-11.
I-Nakamura K. "I-Aniracetam: inoveli yayo yokwelashwa okungase kube khona ekuhlukuneni okungasebenzi okuyisibindi ngenxa yokutholakala kwemithi yakamuva." I-CNS Drug Rev. 2002 Spring; 8 (1): 70-89.
Nakamura K, Pageswa M. "Imiphumela ye-Aniraolytic ye-aniracetam ezinhlobonhlobo ezintathu ezihlukene zegundane zokukhathazeka kanye nendlela engaphansi kwayo." I-Eur J Pharmacol. 2001 Meyi 18; 420 (1): 33-43.
Nakamura K, Tanaka Y. "Imiphumela efana ne-Anti-stress-like of aniracetam kumagundane asebekhulile nemodi yayo yesenzo." I-Psychopharmacology (i-Berl). 2001 Nov; 158 (2): 205-12.
Ukuziphendulela: Ulwazi oluqukethwe kule sayithi luhloswe ngezinjongo zemfundo kuphela futhi aluthathi iseluleko, ukuxilongwa noma ukwelashwa ngudokotela olayisensi. Akuhloselwe ukumboza zonke izinyathelo zokuqapha, ukusebenzisana kwezidakamizwa, izimo noma imiphumela emibi. Kufanele ufune ukunakekelwa okusheshayo kwezokwelapha kunoma yiziphi izinkinga zezempilo bese uthintana nodokotela wakho ngaphambi kokusebenzisa enye imithi noma wenze ushintsho ohlelweni lwakho.