Noma kunjalo bekungabaza, kodwa kungase kudingeke ukudubula ngaphansi kokunakekelwa udokotela
I-Melatonin iyi-hormone ekhishwe yi-pineal gland-i-teeny gland etholakala ngaphakathi kobuchopho bakho. Nakuba i-melatonin idlala indima eminingi, iyaziwa kakhulu ngendima yayo ekulawuleni ukulala / ukuhamba kwayo.
Ucwaningo seluthole ukuxhumana phakathi kwamazinga aphansi we-melatonin nemigraines . Ngokuqondile, abantu abane-migraine abangapheli bathole ukuthi banamazinga aphansi e-melatonin kunelabo abane-migraines episodic.
Ngaphezu kwalokho, izifundo zithole umehluko kumazinga e-melatonin kuma-migraineurs ngokususelwa ekuhlaselweni kwawo-amazinga aphansi e-melatonin ezinsukwini zokuhlaselwa kwe-migraine uma kuqhathaniswa nezinsuku ezingenayo i-migraines.
Ngenxa yalokhu okutholwe, abacwaningi sebeqalile ukubona ukuthi ukuxhaswa kwe-melatonin kungasiza ekuvimbeleni imithi.
I-Melatonin ku-Migraine Prevention
Ngo-2016 isifundo esisodwa ku- Journal of Neurology, Neurosurgery & Psychiatry , abahlanganyeli abangaba ngu-180 abane-migraine babengahlelekile ukuthola i-3mg i-melatonin, iphilisi ye-placebo, noma i- amitriptyline engu- 25mg njalo kusihlwa ngaphambi kokulala. Abahlanganyeli balandelwe amasonto angu-12. Imiphumela yathola ukuthi i-melatonin yayingcono kune-placebo futhi ifana ne-amitriptyline ekuvimbeleni ukuhlaselwa kwe-migraine. Ngaphezu kwalokho, i-melatonin yayibekezelela kangcono kune-amitriptyline, okusho imiphumela embalwa embi (njengokulala).
Enye isifundo sokusekela kwaba isifundo sezindiza sika-2016 ku- Functional Neurology.
Kulolu cwaningo, abahlanganyeli abangamashumi amane nanye abanezinkinga eziphuthumayo ezinhlobonhlobo ze-tension noma i-migraine bathatha i-melmeniy ye-4mg ngomlomo ngamaminithi angu-30 ngaphambi kokulala njalo kusihlwa izinyanga eziyisithupha.
Imiphumela yathola ukuthi kunokuncipha okukhulu kwenani lezinsizwa kanye nemigqa emva kwezinyanga eziyisithupha zokwelapha, uma kuqhathaniswa nesisekelo sokuqala (ngaphambi kokuqala i-melatonin).
Kubalulekile ukuqaphela nakuba lokhu kukhulunywa okushiwo ku- Functional Neurology kuyisifundo somqhubi. Lokhu kusho ukuthi kwakungekho iqembu lokulawula, ngakho abahlanganyeli babeyazi ukuthi bathatha i-melatonin. Ngamanye amazwi, umphumela we-placebo ungase udlale indima lapha.
Futhi, akuwona wonke ucwaningo oye wabonisa inzuzo ekunciphiseni i-migraines ne-supplementation ye-melatonin. Isibonelo, ngo-2010 isifundo se- Neurology , abahlanganyeli abangu-46 abane-migraine babenomsebenzi wokuthola iphilisi ye-placebo noma i-2mg ye-melatonin ekhulisiwe ngaphambili ngaphambi kokulala amasonto angu-8.
Imiphumela yabonisa ukuthi ngenkathi i-melatonin nephilisi ye-placebo zombili zenza ukuncipha kwemigraines, kwakungekho nhlobo phakathi kwalaba ababili. Ngamanye amazwi, i-melatonin ayitholakalanga ukuthi ingcono kune-placebo.
Abanye ochwepheshe bangase bathi lolu cwaningo lunezinamba ezimbalwa, okufaka phakathi isikhathi esifushane (amaviki ayisishiyagalombili) futhi ngaphezulu kunomphumela we-placebo okwakulindeleke ocwaningweni.
Ngakho-ke, Ingabe i-Melatonin isebenza ekuvimbeleni ama-Migraines?
Kunzima ukusho ngokuqinisekile ngoba izifundo zisebenzise ukulinganisa okuhlukene kwe-melatonin (2mg ngokumelene no-3mg kuya kwe-4mg), ukwakheka okuhlukile (ukukhululwa okusheshayo nokukhipha okwesikhashana) kanye nezikhathi ezihlukile (izinyanga ezimbili kuya kwezinyanga ezintathu kuya kweziinyanga ezingu-6).
Ngaphezu kwalokho, ochwepheshe abazi kahle ukuthi i-melatonin ixhunyaniswa kanjani ngqo ne-migraines. Abaningi bacabanga ukuthi ukwesekwa kwe-melatonin kuthuthukisa ubuthongo, futhi ukulala okungalaleli noma ukulala ngokwanele kuwumkhuba ovamile we-migraine trigger .
Lokhu kusho konke, kuyilapho kudingwa izifundo ezengeziwe ukuze kukhishwe indima ye-melatonin ekuvimbeleni kwe-migraine, ungamangali uma udokotela wakho ekunika ukulungele ukuzama i-melatonin ebusuku.
I-edge of melatonin itholakala ngaphezu kwe-counter, engabizi futhi ngokuvamile ibekezelela. Ukuphazamiseka ukuthi ngenxa yokuthi i-melatonin iyisibonelelo, ayilawulwa yi-FDA.
Kungase kubangele ukukhathala komngane kanye nesizungu futhi uhlanganyele neminye yemithi yakho.
Izwi elivela
Nakuba idatha yesayensi isekela indima ye-melatonin ekuvimbeleni i-migraine akuyona enamandla njengoba ochwepheshe bengathanda, i-melatonin ingadinga ukudubula. Yiqiniso, njenganoma isiphi isisetshenziswa, i-vitamin, noma imithi, kubalulekile ukuthatha kuphela i-melatonin ngaphansi kokuqondiswa kukadokotela wakho.
> Imithombo:
> Alstadhaug KB, Odeh F, Salvesen R, Bekkelund SI. I-prophylaxis ye-migraine ne-melatonin: isilingo esilawulwa ngokungahleliwe. I-Neurology . 2010 Okthoba 26; 75 (17): 1527-32.
> Bougea A, Spantideas N, Lyras V, Avramidis T, Thomaidis T. Melatonin 4mg njengendlela yokwelashwa kwe-prophylactic yamakhanda oyinhloko: isifundo somqhubi. Funct Neurol . 2016 Jan-Mar; 31 (1): 33-7.
> I-Gelfand AA, i-Goadsby PJ. Indima ye-melatonin ekwelapheni ukukhathazeka okungenhloko kwekhanda. Izinwele . 2016 Sep; 56 (8): 1257-66.
> Goncalves AL, Martini Ferreira A, Ribeiro RT, uZukerman E, Cipolla-Neto J, Peres MF. Isivivinyo somtholampilo esingaguquguquki siqhathanisa ne-melatonin 3mg, i-amitriptyline 25mg ne-placebo yokuvimbela i-migraine. J Neurol Neurosurg Psychiatry . 2016 Oct; 87 (10): 1127-32.
> Masruha MR et al. Amazinga e-Urinary 6-sulphatoxymelatonin acindezelekile ekuguleni okungapheli nokuncintisana okuningana. Izinwele . 2010 Mar; 50 (3): 413-9.