Indima Yegazi Elimhlophe Ekukhiqizeni I-Histamine
I-Basophils ingenye yezinhlobo ezingavamile zezingqamuzana zegazi ezimhlophe ezikhonza njengengxenye yesistimu yethu yomzimba . Babala ngamaphesenti ayisithupha kuphela amangqamuzana egazi amhlophe okwamanje badlala indima ebalulekile ekuvikeleni komzimba kwangaphambili.
Ama-Basophil enza imisebenzi eminingana ebalulekile. I-heparin eyenza ukuthi igazi lingavali ngokushesha futhi lingadla "izidumbu" nge-process ebizwa nge-phagocytosis.
Kodwa mhlawumbe indima ebaluleke kunazo zonke abayidlalayo ekusebenziseni okuthile okuvuthayo, ikakhulukazi leyo ehilela ukugula.
Ama-Basophil no-Allergies
Ama-Basophil ayingxenye yesimiso sokuvikela amasosha omzimba esiyingozi esiholela ekuphenduleni okungenasici kunoma yini umzimba okubheka ukuthi iyingozi. Ngokungafani nokuzivikela okuthintekayo, okuyinto eyenza impendulo ehlosiwe, imiphumela yokuzivikela yangasese ekuhlaselweni okujwayelekile. Uma kwenzeka lokhu, umzimba ungathola ukuvuvukala, uhlobo lokuzivikela okuvame ukuveza ukuvuvukala, ubuhlungu, umkhuhlane kanye nokukhathala.
Ngaphezu kwalokhu, ama-basophil akhiqiza into ebizwa ngokuthi i-histamine ebangela ukuthi imithwalo yegazi ihlaziye ukuze kuvumele ukuba amasosha omzimba avikelekile esiteshini sokutheleleka.
Kodwa lesi akusona isikhathi kuphela lapho ama-histamine akhiqizwa khona. Lapho umzimba uthola izifo ezithile, isimiso somzimba sokuzivikela singakwazi "ukuphendula ngaphezulu" futhi senze ukukhululwa kwama-histamine, okubangele ukuvuvukala, ukunyundela, nezinkinga zokuphefumula esizihlanganisa nezifo.
Ukuhlangana Phakathi Kwase-Basophil ne-Asthma Izimpawu
Inombolo ye-basophil egazini ingahluka. Uma izinombolo ziphansi kakhulu, sisho ukuthi lowo muntu une-basopenia. Uma uphakeme kakhulu, lowo muntu une-basophilia. I-Basophilia inokukhathazeka ngokukhethekile kubantu abane-asthma njengoba ukwanda kwezinombolo ze-basophil kungashintsha ekukhiqizeni okwandiswa kwama-histamine.
Ngokuvamile, i-basophilia ingavamile kodwa umuntu angase avele kubantu abanezifo ezithile ze-bacterial or viral, isifo sikashukela, isifo samathambo, i-eczema, noma i-hypothyroidism. Ngenxa yokwanda kwezinombolo zamaseli, i-basophilia ingase ihlotshaniswe nokuwohloka kwezimpawu kubantu abane-asthma. Lezi zingabandakanya:
- Ukuvuvukala okukhulu kwemaphaphu
- Ukwehliswa kwamapayipi emoyeni (i- bronchoconstriction ), okwenza kube nokushisa, ukuqina kwesifuba nokuphefumula
- Ukwenziwa ngokweqile kwe-mucus, okwenza ukukhwehlela nokuvimbela ukuphefumula
I-Basophilia ibuye ibonakale kuleso sifo njenge-atopic dermatitis, isifo sofuba esiswini (IBD), i-hemolytic anemia, i-lemonemia engavamile, nesifo se-Hodgkin.
Indima ye-Basophils ekuphatheni i-Asthma
Nakuba kungabonakali ukuthi yiyiphi indima, uma ikhona, ukuhlolwa kwe-basophil emtholampilo (BAT) kungase kutholakale ekuxilongweni noma ngesifo se-asthma. Kodwa-ke, kubonisa isidingo sokucwaninga okuqhubekayo ukuze kuqondwe izindlela ze-molecular of asthma kanye ne-allergies. Ngokwenza kanjalo, izindlela zokwelapha ezintsha nezindlela zokwelapha zingase zenziwe (kufaka phakathi izindlela zokwehlisa impendulo ye-basophil-histamine).
Lokho esikwaziyo yilokhu: ngokuphathwa okufanele nokuqapha okuqhubekayo impilo yomuntu, izimpawu eziqhubekayo ze-asthma zinganciphisa noma zivinjelwe.
Ngokuphambene nalokho, i- asthma engalawulwa kahle (ebangelwa ukulingana okunganele noma ukwelashwa okungalungile) kungabangela umonakalo ongapheli ngisho nangokonakalisa umonakalo.
Ekugcineni, indlela engcono kakhulu yokwandisa ukwelashwa kwe-asthma ukugcina impilo enhle , futhi lokho kuhlanganisa ukuvakashelwa njalo kudokotela wakho.
> Imithombo:
> Hoffmann, J .; I-Knol, E .; UFerrer, uL .; et al. "Izinzuzo Nezidingo Zesivivinyo SaseBasophil Clinic (BAT)." Imibiko Yezifo Zezifo Eziphuthumayo Nama-Asthma . 2016: 16 (8): 56.
> Siracusa, M .; Kim, B .; I-Spergel, J .; kanye nama-Artis, D. "Ama-Basophils nokuvuvukala kwe-allergenic." I-Journal Yokuzifola Kwegazi Ne-Immunology Yezokwelapha . 213. 132 (4): 789-801.