Ukuqaphela Nokuphatha Lesi Sigaba Sokuchaza Ingculaza
Sibutsetelo
Ekuqaleni kwesifo se-AIDS sokuqala-kuya ngasekupheleni kwawo-1980, umdlavuza wesikhumba ongavamile obizwa ngokuthi i- Kaposi's sarcoma (KS) waba uphawu lokutheleleka nge-HIV. Lokhu, kanye nokulahlekelwa kwesisindo esikhulu, kuchaza lokho abaningi ababhekwa ngokuthi "ukubukeka kwe-AIDS." Sasibukela amafilimu afana neFiladelphia , lapho uhlaka lukaTom Hank oluthile oluthile lwaluthambile khona izilonda ze-KS ezimnyama.
Namuhla, sibona i-KS encane kakhulu kunangaphambili ngenxa yokusetshenziswa kabanzi kwezidakamizwa ze- antiretroviral , kodwa kusekhona into engabonakala emazweni angathuthukile noma kubantu abangaphathwa ngesifo sabo.
I-sarcoma yeCapisi (ebizwa nangokuthi i-Kaposi sarcoma) iyisisu esibangelwa i-herpesvirus yabantu (i-HHV8) ebonakala ngokuyinhloko esikhumbeni nasemlonyeni, kodwa ingathinta nezitho zangaphakathi. I-KS ngokuvamile iveza izindawo ezincane ezinokulimaza ezingenabuhlungu noma ezibuhlungu. Ikakhulukazi ezinyathelweni zokuqala, zivame ukuphutha ngenxa yezivunguvungu ezilula.
Uma kuhlukaniswe isikhumba, i-KS ayibhekwa njengengozi yokuphila. Kodwa-ke, uma izilonda zisakaze emgodleni wamathumbu, amaphaphu, ubuchopho noma ezinye izitho zangaphakathi, zingaba sína futhi zingabulala.
Ukuthutha
I-HHV8 idluliselwa ngoxhumano lobucansi, amathe, ukumpontshelwa igazi, nokuguquka komzimba. "Ukumangaza okujulile" kubhekwa njengendlela ephumelelayo yokudlulisa, nakuba izinga lamadoda angama-gay lingaphezu kwezikhathi eziyisishiyagalombili eziphakeme kunamanye amaqembu abantu.
Izindaba ezinhle ukuthi ngenkathi i-KS ivamile, lesi sibalo sibonakala sinciphile.
Izimpawu Nezibonakaliso
Izilonda ze-KS zivela njengezichaziwe, izindawo ezimnyama esikhumbeni noma ngaphakathi komlomo. Ukubukeka kwabo okunjengobuhlungu ngezinye izikhathi kwenza kube nzima ukubona. Njengoba ziqhubeka, zingaba mnyama futhi zivele njengama-nodules aphakanyisiwe.
Isivivinyo esilula ukuhlukanisa i-KS lesion kusuka kokulimaza ukucindezela indawo ngomunwe munye. Umbala omnyama we-crude uzohamba nomfutho wezinsiza, kepha i-KS lesion ngeke ikwazi.
Kodwa-ke, indlela yodwa yokuthola i-KS ngokucacile ngokwenza i-biopsy. I-biopsy ihlanganisa ukukhishwa kwesampula encane ye-lesion, ehlolwe ngaphansi kwe-microscope.
Uma i-KS isakaze engxenyeni yangaphakathi, ingabonisa ngezindlela eziningana kuye ngokuthi isayithi lokutheleleka.
I-KS yePhuzu lomathumbu:
- Ubuhlungu besisu
- Uhudo
- Ukuvimbela emathunjini
- Ukulahlekelwa kwesisindo
- Nausea / ukuhlanza
- Izitofu zamanzi
- Ukuvuthwa kwegazi
I-KS yendlela yokuphefumula:
- Isikhukhula
- Ubuhlungu besifuba
- Ukuphelelwa umoya
- Ukuphefumula okunzima
- Ukuvinjelwa kwamapulmonary
- Ukushaya igazi
- Ubuhlungu besifuba
Ukwelapha
Ngenkathi i-KS ingakwazi "ukuphulukiswa," ingaphathwa kahle. Ukubuyiselwa kwe-immune function kungaphinde kuguqulwe isimo ngokusebenzisa i- antiretroviral therapy (ART) ngesikhathi sokuxilongwa. Kubantu abanezifo ezithuthukisiwe, kungathatha isikhathi kepha kungavamile ukuthuthukisa isimo kufanele i-ART yansuku zonke ilandelwe.
Uma i-ART kuphela ingayiphatha izilonda, ezinye izindlela zokwelashwa zingasetshenziswa ngokubambisana ne-ART. Lezi zingabandakanya:
- Amakhemikhali e-anti-cancer amakhemikhali asetshenziselwe ukwelapha nokunciphisa izilonda ze-KS, ikakhulukazi lezo zipheshana zokuphefumula nezomathumbu. Imiphumela emibi ingaba nzima, nge-nausea, ukuhlanza, i-anemia, nokulahleka kwezinwele.
- Izilonda zesikhumba eziqhwayo ngokweqile nge-nitrogen enamandla zibhekwa njengeziphumelelayo ngezilonda ezincane, nakuba zingasebenzi kangako ngama-nodules akhukhumezekile.
- Ukukhishwa kokuhlinzwa kwezilonda ngezinye izikhathi kwenziwa, nakuba ngokuvamile kunganconywa njengoba ukubhula kungasakazeka nemiphetho ebonakalayo, ebonakalayo.
Kubalulekile ukuqaphela ukuthi izilonda ze-KS ziphinde zivele, ikakhulukazi kubantu abanegazi elikhulu lokucindezelwa, uma i- ART ingatholakali .
Ukuvimbela
Njengoba kunikezwe indlela yokudlulisela kanye nokuntuleka kwamathuluzi okuhlola i-HHV8, kunendlela encane yokugwema ukutheleleka. Uma kuthiwa, ukuxilongwa kokuqala kanye nokwelashwa kwe-HIV kungaqinisekisa ukuthi izivikeli zomzimba zomuntu zihlala zingaguquki, ngaleyo ndlela ukunciphisa ingozi ye-KS cishe emazingeni anganaki.
Imithombo:
U-Antman, K. noTshints, Y. "I-Kaposi's Sarcoma." I-New England Journal of Medicine. 2002: 342 (14): 1027-1038.
I-Cattelan, A .; I-Calabrò, M .; De Rossi, A .; et al. "Umphumela wesikhathi eside wokutholwa kwengculaza we-Kaposi's sarcoma ngesikhathi kusetshenziswa ukwelashwa kwama-antiretroviral kakhulu." I- International Journal of Oncology. 2005; 27 (3): 779-785.