Ama-cereamide ayinhlobo lamafutha atholakele ngokwemvelo ku- stratum corneum , ungqimba lwangaphandle lwesikhumba. Kanye ne-cholesterol namafutha ama-acids mahhala (ezinye izinhlobo ezimbili zamafutha ezitholakala ngokwemvelo esikhumbeni sakho), ama-ceramide asiza ukugcina amangqamuzana esikhumba ndawonye. I-ceramide ibalulekile ekusebenzeni okujwayelekile kwesendlalelo somgoqo wesikhumba futhi udla indima ebalulekile ekusizeni isikhumba sakho sigcine umswakama.
Njengamazinga e-ceramide ehla ngokuguga okuvamile, isikhawulo sesikhumba singaphazanyiswa, okuholela ekubomvu, ekomile nasekucaseni isikhumba.
Ukusetshenziswa kwama-Ceramide
Uma isetshenziswe ngqo esikhumbeni ngezilonda neminye imikhiqizo ye-skincare, i-ceramide kuthiwa iyasiza ekubuyiseleni isikhala sesikhumba, usizo ekwelapheni izimo zesikhumba ezifana ne- eczema ne- psoriasis , ukuthuthukisa isikhumba esomile, nokunciphisa ukubukeka kwemigqa emihle nezinye izimpawu yokuguga.
Izinzuzo zamaCeramide
Nakhu ukubuka okunye okufundwayo okufundwayo ekusetshenzisweni kwama-ceramide ngezinkinga zesikhumba:
I-Eczema
Eyaziwa nangokuthi i-atopic dermatitis, i-eczema yisimo esibangela isikhumba ukuba sithukuthele futhi sishaye. Ucwaningo lubonisa ukuthi abantu abane-eczema bangaba namazinga aphansi ama-ceramide engqimba ephezulu yesikhumba sabo. Ezinye izifundo zibonisa ukuthi ukusetshenziswa kwemikhiqizo ye-skincare equkethe i-ceramide kungase kuthuthukise izimpawu ze-eczema.
Ngokwesibonelo, ngocwaningo luka-2016, abacwaningi bathola ukuthi ukhilimu oqukethe i-ceramide ne-magnesium kuthuthukise isikhumba se-hydration futhi kunciphisa ubukhulu bezilonda zesikhumba (isikhumba esomile, esinyanyisiwe noma isikhumba) kubantu abane-dermatitis emnene kuya eyingqayizivele, uma kuqhathaniswa ne-hydrocortisone ukhilimu kanye ukhilimu obandayo ovame ukusetshenziswa.
I-Psoriasis
I-Psoriasis iphinde ihlotshaniswe namazinga aphansi ama-ceramide ezinsikeni zesikhumba (ephakanyisiwe, ama-red patches ahlanganiswe nezikali), okuholela ekusebenzeni okungavinjelwe kwesikhumba. Ucwaningo olunyatheliswa ku- Dermatologic Therapy ngo-2015 lwahlola ukusebenza kwe-linoleic-acid-ceramide moisturizer ngokuhambisana ne-corticosteroid yama-topical (uma kuqhathaniswa ne-corticosteroid ye-topical yedwa) kubantu abane-psoriasis.
Ngemuva kwezinyanga eziyisishiyagalolunye zokwelapha, ubukhulu bezimpawu zancipha kulabo abasebenzisa i-linoleic-acid-ceramide moisturizer.
Isikhumba esikhulayo
I-Ceramide ingasiza ekuvikeleni isikhumba esomile esihlobene nokuguga, ngokusho kocwaningo olwanyatheliswa kuyi- International Journal of Immunopathology and Pharmacology . Ekuvivinyweni kwabesifazane abangu-20 abanempilo, abalobi bezocwaningo banquma ukuthi ukusebenzisa ukhilimu onamakhemikhali kusize ukuthuthukisa umsebenzi wokuvimbela isikhumba nokwandisa ukumelana nesifo esikhulayo esikhulayo.
I-Skin Irritation
Ama-ceramide angasiza ukuvikela isikhumba kwezinye izinto ezicasulayo, isifundo esashicilelwe kuyi- International Journal of Dermatology sikhombisa. Ekuhlolweni okubandakanya abesifazane abanesikhumba esinempilo, abacwaningi bathole ukuthi ukusebenzisa uketshezi olunamanzi e-ceramide esikhumbeni kwasiza ukuthuthukisa umsebenzi wokuvimbela isikhumba, ukwandisa isikhumba se-skin, nokuvikela ukucasuka okubangelwa ukuvezwa kwe-lauryl sulfate, i-synthetic chemicals etholakala emanzini amaningi omuntu siqu- imikhiqizo yokunakekelwa.
Ukuthenga ama-Ceramide
Abaningi be-skincare ochwepheshe batusa ukukhetha imikhiqizo ene-ceramide equkethe i-cholesterol nama-fatty acids mahhala ngesilinganiso esithile. Ucwaningo lubonisa ukuthi kumele kube khona ukulinganisela kwazo zonke izinhlobo ezintathu ukuze umkhiqizo oqukethe i-ceramide usebenze ngokuphulukisa isikhumba.
Ama-massage, ama-creams, ama-lotions, ama-cleaners, nama-formula wokunakekelwa kwesikhumba aqukethe ama-ceramide athengiswa ezindaweni eziningi zokudayisa izidakamizwa nezitolo ezithwala imikhiqizo ye-skincare. Amanye ama-creamide creams nama-moisturizers atholakale ngemithi kadokotela.
Ukuphepha
Ngenkathi ama-ceramide atholakala kabanzi emikhiqizo yokunakekelwa kwesikhumba, asikwazi ngokwanele mayelana nokuphepha kwamakhemikhali e-ceramide athathwa ngomlomo. Amazinga aphezulu egazi ka-ceramide aye ahlanganiswa nezifo eziningi, ezifana nesifo senhliziyo nesifo sikashukela.
Izithako zokudla eziqukethe imithombo yezitshalo ze-ceramide, ezifana ne-konjac, kuthiwa zithuthukisa umsebenzi wokuvimbela isikhumba futhi zisiza ukuphatha izimo ezithile zesikhumba.
Kodwa-ke, okwamanje kuntuleka kocwaningo olusekela isimangalo sokuthi ama-ceramide angaphulukisa isikhumba uma edlalwa efomini lokugcwalisa ngomlomo.
Ungathola amathiphu ekusetshenzisweni izithako lapha , kepha kuze kube yilapho sesiyazi okuningi, izithako ze-ceramide zomlomo kufanele zigweme.
Izwi elivela
Ama-ceramide atholakala eziningana ze-moisturizers nemikhiqizo ye-skincare. Nakuba ucwaningo olwengeziwe luyadingeka empilweni yabo yokuphulukisa ezimweni ezifana ne-psoriasis, ukusebenzisa i-moisturizer nge-ceramide kungasiza ukuhambisa isikhumba esomile nokunciphisa ukuhlobisa okuhambisana nesikhumba esomile.
Uma unesifo sesikhumba, thintana nodokotela wakho we-dermatologist ukuze ubone ukuthi imikhiqizo ye-ceramide yama-topical iyilungele yini uhlobo lesikhumba sakho futhi usizo lokukhetha umkhiqizo.
Ngaphandle kwama-ceramide e-topical, iningi lemikhiqizo yemvelo, njenge- oli yama-neem namafutha we- argan , ingavikela futhi isikhumba esomile futhi ikhuthaze ukuphulukiswa kwezimo ezithile zesikhumba.
> Imithombo:
> Di Marzio L, Cinque B, Cupelli F, De Simone C, Cifone MG, Giuliani M. Ukwandisa amazinga esikhumba-ceramide ezifundeni ezindala ngemuva kwesicelo esifushane se-sphingomyelinase ye-bacterial from Streptococcus thermophilus. I-Int J Immunopathol Pharmacol. 2008 Jan-Mar; 21 (1): 137-43.
> Huang HC, Chang TM. I-Ceramide 1 ne-ceramide 3 isenzo se-synergistically esikhumbeni se-hydration kanye nokulahlekelwa kwamanzi kwe-transepidermal we-sodium lauryl sulfate-isikhumba esicasulayo. Int J Dermatol. 2008 Aug; 47 (8): 812-9.
> Koppes SA, uCharles F, uLammers L, et al. Ukusebenza kwe-Cream equkethe ama-Ceramide ne-Magnesium ekwelapheni kwe-Dermatitis elula yokulinganisa i-Dermatitis e-Atopic: I-Trial-Double blind, Emollient- ne-Hydrocortisone. Acta Derm Venereol. 2016 Nov 2; 96 (7): 948-953.
> Liu M, Li X, Chen XY, Xue F, Zheng J. Topical ukusetshenziswa kwe linoleic acid-ceramide equkethe moisturizer kubonisa izinsiza zokwelashwa kanye nokuvimbela psoriasis vulgaris: isilingo esilawulwa ngokungahleliwe. Dermatol Ther. 2015 Nov-Dec; 28 (6): 373-82.
> Ukuziphendulela: Ulwazi oluqukethwe kule sayithi luhloswe ngezinjongo zemfundo kuphela futhi aluthathi iseluleko, ukuxilongwa noma ukwelashwa ngudokotela ovunyelwe. Akuhloselwe ukumboza zonke izinyathelo zokuqapha, ukusebenzisana kwezidakamizwa, izimo noma imiphumela emibi. Kufanele ufune ukunakekelwa okusheshayo kwezokwelapha kunoma yiziphi izinkinga zezempilo bese uthintana nodokotela wakho ngaphambi kokusebenzisa enye imithi noma wenze ushintsho ohlelweni lwakho.