Iningi labantu liphendukela kumithi ephezulu kakhulu lapho bebhekana nokuhlasela okunzima kwe- migraine noma ikhanda lokuhlukunyezwa kohlobo lwezinkinga . Lokhu kunengqondo, njengoba imithi engaphezu kwemithi efana ne-Tylenol (i-acetaminophen) kanye ne-nonsteroidal anti-inflammatories (ama-NSAID afana ne-ibuprofen noma i-aspirin) ayatholakala kalula, angabizi, futhi awadingi ukuvakasha kukadokotela. Kukhona izifundo zesayensi ezisekela inzuzo nokuphepha kwazo ekuphatheni i-epradic migraine noma inhlobonhlobo yekhanda lokuhlukumezeka.
Lokho kusho ukuthi, lapho usebenzisa indawo yekhemisi yangakini, cishe uye waphawula ukubuyisela ubuhlungu obuningi bokuthi ubuhlungu be-migraines nobuhlungu bekhanda-u-Excedrin. I-analgesic enhlanganisela equkethe iTylenol (i-acetaminophen), i-aspirin, ne-"agent-open" ye-caffeine.
Ngalokho, ungase uzibuze ukuthi i-Excedrin ihle yini (noma ingcono kakhulu) kuneTylenol yodwa, i-aspirin yedwa, noma ibuprofen yedwa ekunciphiseni ikhanda kanye nemigraines.
Ake sihlole lo mbuzo ngemininingwane eminingana, ngoba impendulo ayiyona eqondile njengoba ungayilindela. Ngamanye amazwi, kukhona ukuphakama nokunciphisa ukucubungula lapho ukhetha i-Excedrin njengemithi yakho "yokuhamba" yezinkinga zekhanda noma izinkinga ze-migraines.
I-Upside
Esifundweni sokubuyekezwa ku -Journal of Headache and Pain, inhlanganisela ye-caffeine ene-analgesic efana ne-Tylenol (i-acetaminophen), i-aspirin (i-acetylsalicylic acid), ne-ibuprofen, yayiphumelele kakhulu ekwelapheni imishanguzo yezinhlanzi nokuhlukunyezwa, uma kuqhathaniswa ne- imithi ye-analgesic yedwa.
Kodwa-ke, ungase umangale uma ufunda ukuthi i-caffeine, ngokwayo, akuyona inhlanzi yokuphumula. Kunalokho, kwandisa umphumela we-analgesics, njenge-aspirin ne-Tylenol, futhi yenza lokhu ngokuthuthukisa ukungena kwabo ngaphakathi kwamanzi.
Ucwaningo lubonisa umphumela wokunyuka kwe-caffeine kubonakala ngamanani angu-130mg noma ngaphezulu ezinhlokweni ezinhlobonhlobo zezintambo kanye no-100mg noma ngaphezulu ku-migraine.
Njengoba imithi eline-caffeine ene-over-counter iqukethe ama-64 kuya ku-65mg we-caffeine (kufaka phakathi i-Excedrin), sicela uqaphele ukuthi kuzodingeka uthathe amaphilisi amabili e-Excedrin ukuze uthole inzuzo ye-caffeine (okuyisilinganiso esivamile).
Njengebhonasi eyengeziwe, kufanelekile ukuphawula ukuthi ukuhlunga ikhanda e-caffeine ekhanda ikhanda kungaba neminye imisebenzi. I-caffeine iyishukumisayo, okusho ukuthi kuthuthukisa isimo sengqondo, ukuqapha, ukuphathwa kolwazi, ukuqwashisa, ukunakekelwa, kanye nesikhathi sokuphendula.
Ngakho uma uzizwa ukhathele kakhulu noma ucindezelekile ngekhanda lakho, i-Excedrin kungenzeka inganciphisi nje ubuhlungu bakho kodwa ikusize uzizwe unamandla.
Ukwengeza, i-caffeine ithuthukisa i-motility ye-gastric (ukunyakaza ngokomzimba kokudla ngendlela yakho yokugaya). Lokhu kungasisiza ikakhulukazi ama-migraineurs, njengoba umuthi wesisu wesisu unganciphisa ngesikhathi sokuhlasela kwe-migraine, okuholela ekufusweni kwe- nausea kanye / noma nokuhlanza .
I-Downside
Ukunakekelwa kwezokwelapha ngokuvamile akumnyama futhi kumhlophe. Ngamanye amazwi, ubuciko obuyinkimbinkimbi, njengoba akuwona wonke umzimba womuntu nomlando wezokwelapha okufanayo. Ukuze uqinisekise ukuthi imithi ethile ilungile kuwe, kubalulekile ukuba ukhulume kuqala nodokotela wakho.
Okuqhamuka uma udla imishanguzo
Enye indlela yokuthatha i-Excedrin esikhundleni se-Tylenol, i-aspirin, noma i-ibuprofen yedwa ukuthi ungathola imiphumela emibi evela ku-caffeine.
Imiphumela emibi kakhulu yilezi:
- Isisu esibuhlungu
- Isizungu
- Ukwesaba
- I-nausea
Lokho kusho ukuthi lemiphumela emibi ngokuvamile ilula futhi ihlala isikhathi esifushane. Noma kunjalo, uma ungavumi ukubekezelela indebe enamandla yekhofi noma ungene emhlanganweni futhi ukhathazekile ngokuthola kancane, I-Excedrin kungenzeka ukuthi ayiyona into enhle kakhulu ngaleso sikhathi.
I-Caffeine Paradox
Nakuba i-caffeine inganciphisa i-migraines ne-head-type-headaches, izifundo zibonise ukuthi i-caffeine ihlobene nokuthuthukiswa kwe-migraines kanye nokuguqulwa kusuka ku-episodic kuya ku-migraines engapheli (i-migraines engu-15 noma ngaphezulu ngenyanga) -ukuphazamiseka okushiya abaningi bethu .
Ngaphezu kwalokho, ukuhoxiswa kwe-caffeine kungabangela izinhlungu futhi kuholele ekunciphiseni umsebenzi wokuqonda, ukuhlanza inhlanzi nokuhlanza (konke esikhathini esifushane). Nakuba, esikhathini eside, (futhi hhayi ukucindezela isithombe), ukuqeda i-caffeine cishe kuyasiza kubantu abanekhanda.
Ekugcineni, uma uzwela nge-caffeine, bese ufaka i-Excedrin kumkhuba wakho kungenzeka ukuthi akusiyona inketho engcono kunazo zonke "yokuya ekhanda".
Bheka Udokotela Wakho Wokunakekela Okuyinhloko
Kungcono ukuza nesiphakamiso nodokotela wakho wokunakekelwa okuyinhloko noma ochwepheshe bekhanda mayelana nokuthi imiphi imithi engaphezu kwamakhomitha ongayithatha uma uhlakulela ikhanda. Lokhu kungukuthi nakuba iTylenol, i-Excedrin, ne-NSAID zitholakala ngaphandle kwemithi kadokotela, aziphephile kuwo wonke umuntu.
Ngokwesibonelo, ama-NSAID kufanele asetshenziswe kuphela ngaphansi kokuqondiswa okudokotela udokotela uma une-asthma noma izinso, izinhliziyo, noma izinkinga zesibindi. Ukwengeza, ama-NSAID angabangela ukucasuka kwesisu nokuphuma kwegazi ngakho akufanele asetshenziswe abantu abasebenzisa imishanguzo yegazi noma abantu abanomlonda wesisu.
I-aspirini, futhi, noma imikhiqizo equkethe i-aspirin (njenge-Excedrin), akumele iwanikwe izingane, njengoba zingandisa ingozi yengane yokuthuthukisa isifo esibi esibizwa ngokuthi i- Reye's syndrome .
Ngaphezu kwalokho, imithi engaphezu kwe-counter ingase ihlanganyele nemithi yakho yesiguli. Yingakho kubalulekile ukwazisa udokotela wakho yonke imithi oyithathayo, kubandakanya noma yiziphi amavithamini noma izithako.
Okokugcina, imishanguzo eminingi engaphezu kwele-counter iqukethe iTylenol (i-acetaminophen) , njengemithi ebanda futhi yebo, i-Excedrin. Udokotela wakho angenza isiqiniseko sokuthi awukhohlisi ku-Tylenol okuyinto engathà sina futhi kungaholela ekuhlulekeni kwesibindi .
Izwi elivela
Ngesikhathi ucwaningo lubonisa ukuthi ama-analgesics aqukethe i-caffeine afana ne-Excedrin asebenza ngokuphumelelayo ekunciphiseni imishanguzo ye-migraines nezinkinga zokuhlukumezeka kunokuba uthathe iTylenol, aspirin, noma ibuprofen yedwa, okungenzeka ukuthi akunjalo kuwe. Ekugcineni, uthembela emathunjini wakho futhi wenze okukusebenzelayo (nge "OK" ngudokotela wakho).
Okokugcina, kungakhathaliseki ukuthi usebenzise imishanguzo engaphezu kweyiphi, qaphela ukuba uyibeke ezinsukwini ezingaphansi kwezinsuku ezimbili ukuya kwezintathu ngesonto. Ngale ndlela ungagwema imithi yokwelapha ngokweqile , lapho umuntu eqala ikhanda elikhukhumezayo-i-double whammy, kanye nenkinga ekhanga kakhulu ukuphatha.
> Imithombo:
> Derry CJ, uDerry S, Moore RA. I-caffeine njenge-adjuvant e-analgesic yezinhlungu ezinzima kubantu abadala. I-Cochrane Database Syst Rev. 2014 Dec 11; (12): CD009281.
> Lee MJ, Choi HA, Choi H, Chung CS. Ukwehla kwe-caffeine kuthuthukisa ukwelashwa okujulile kokufudumala: isifundo esisekelwe emtholampilo esingaba khona. I-J Headache Pain. 2016; 17 (1): 71. i-doi: 10.1186 / s10194-016-0662-5.
> Lipton RB, Diener HC, Robbins MS, Garas SY, Patel K. Caffeine ekulawuleni iziguli ezinezinwele. I-J Headache Pain. 2017; 18 (1): 107. i-doi: 10.1186 / s10194-017-0806-2.
> Ngaphambi kukaJJ, uCodispoti JR, Fu M. Uhlolo olulawulwa ngokungahleliwe, olulawulwe nge-placebo lwe-acetaminophen ukwelashwa kwekhanda le-migraine. Izinwele . 2010; 50 (5): 819-833. i-doi: 10.1111 / j.1526-4610.2010.01638.x.
> Taylor FR. (2017). Inhlobonhlobo yezintambo ezinhlobonhlobo kubantu abadala: Ukwelashwa okunamandla. U-Swanson JW, u-ed. Kusesikhathini. Waltham, MA: UpToDate Inc.