I-Vitamin B9 nayo ibizwa nangokuthi i-folic acid noma i-folate. Ngokuvamile, i- folate yileli gama le-vitamin B9 elitholakala ngokwemvelo ekudleni, kuyilapho i- folic acid igama le-supplement synthetic elongezwa ekudleni nasevithamini.
Inani elilinganayo le-folic acid liye laphakanyiswa ukuba kuvinjelwe ukukhubazeka kokuzalwa njenge- spina bifida . Kodwa, wayazi yini ukuthi ukuthola i-folate ngokwanele kuhlotshaniswe nenengozi enciphise yokuthuthukisa u-dementia?
Ucwaningo
Ucwaningo olwenziwe lubandakanye abantu abangu-166: abangu-47 kubo abatholwa ukuthi bane- Alzheimer's , 41 abane- dementia ye-vascular and 36 nge-diagnosis ye- dementia . Ukwengeza, abantu abangu-42 ababengenakho ukukhubazeka kwengqondo nabo babandakanywa esifundweni. Abacwaningi balinganisa amazinga omuntu ngamunye abahlanganyeli futhi, ngemva kokubukeza imiphumela, bathola ukuthi abantu abane-dementia babe namazinga aphansi kakhulu e-folic acid uma kuqhathaniswa nalabo abangenayo i-dementia. Imiphumela yayifana nalezi zinhlobo ezintathu ze-dementia ezifakwe kulolu cwaningo.
Ucwaningo lwesibili lubuyekeze izifundo eziningi zocwaningo futhi lwaphetha ngokuthi amazinga aphansi e-folic acid ayecacile ahlotshaniswa nokuba khona kokubili ukukhubazeka okunengqondo nokucushwa kwengqondo.
Ucwaningo lwesithathu olugxile kuphela kwabesifazane bathola ukuthi amazinga aphansi e-folic acid ahlotshaniswa nengozi ephezulu yokukhubazeka okungacabangi.
Ingabe Ukwengeza I-Folic Acid Ekudleni Kakho?
Mhlawumbe, nakuba imiphumela engapheli kuze kube manje.
Olunye ucwaningo olubandakanya abantu abadala abadala abangu-900 abahlala emakhaya abo bathola ukuthi ukwesekwa isikhathi eside ngevithamini B12 kanye nokukhumbuza i- folate inkumbulo .
Esinye isifundo esasihilela ukuphatha i-folic acid kuma-rats sathola ukuthi inkumbulo yesikhathi esifushane neyesikhathi eside yenze ngcono. (Kungakhathaliseki ukuthi lokhu kuzohunyushwa kubantu akuziwa.)
Kodwa-ke, ezinye izifundo azitholanga umehluko omkhulu ekuqaphelweni kwabantu abadliwa yi-folic acid. Ngokusobala, ucwaningo oluningi luyadingeka kule ndaba.
Iziphetho
Abantu abanezilinganiso ezifanele ze-folate ngokuvamile banengozi engezansi yokuwohloka komqondo. Nakuba kungacacile ukuthi i-folic acid supplementation izokwehlisa ingozi, ukudla okunempilo (kufaka phakathi imifino eluhlaza emifino ejwayelekile ngokwemvelo) ibuye ihlotshaniswe nengozi enciphise yokugula komqondo.
Imithombo:
Ukuhlola Okudala Okucwaninga. 2015 Jul; 22: 9-19. Ukuqoqa nokuguga: Ukusebenza ngokukhubazeka okunengqondo, ukucindezeleka komqondo nokucindezeleka. http://www.ncbi.nlm.nih.gov/pubmed/25939915
I-Alzheimer's and Dementia. 2005 Jul; 1 (1): 11-18. Inengozi yokunciphisa isifo se-Alzheimer ngokudla okuphezulu: I-Baltimore Longitudinal Study of Aging. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375831/
I-American Journal of Nutrition Clinic. 2012 Jan; 95 (1): 194-203. I-oral folic acid ne-vitamin B-12 ukwesekwa ukuvimbela ukwehla kwengqondo kubantu abadala abadala abahlala emphakathini abanezimpawu ezicindezelayo - i-Beyond Aging Project: isilingo esilawulwa ngokungahleliwe. http://www.ncbi.nlm.nih.gov/pubmed/22170358
I-Cochrane Database yezibuyekezo zesistimu. 2008 Okthoba 8; (4): CD004514. I-folic acid ene-vitamin B12 noma engenayo yokuvimbela nokwelashwa kwabantu asebekhulile nabomisiwe. http://www.ncbi.nlm.nih.gov/pubmed/18843658
Journal of Iranian of Basic Medical Science. 2012 Nov; 15 (6): 1173-9. Imemori nokuthuthukiswa kwezimoto ngcono nge-folic Acid supplementation kuma-rats angamadoda amadala enempilo. http://www.ncbi.nlm.nih.gov/pubmed/23653847
Journal of the Academy of Nutrition and Dietetics. 2015 Feb; 115 (2): 231-41. I-Folate, i-vitamin B-6, kanye nokukhubazeka kokungenwa kwengqondo nokunakekelwa kwengqondo nokukhathazeka okungenzeka ku-Study's Memory Initiative. http://www.ncbi.nlm.nih.gov/pubmed/25201007
Izikhungo zezempilo zikazwelonke. Ifolda. NgoDisemba 14, 2012. https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/
I-polski merkuriusz lekarski: inhlangano i-Polskiego Towarzystwa iLekarskiego. 2013 Oct; 35 (208): 205-9. [Ukubaluleka kobuciko be-folic acid ku-pathogenesis ye-vascular, mixed mix and Alzheimer's disease dementia]. http://www.ncbi.nlm.nih.gov/pubmed/24340890