Ubani owayengu-Alois Alzheimer?
I-Alois Alzheimer yilowo ohlonishwayo ngokuthola isifo se-Alzheimer ngo-1906.
U-Alois wazalwa ngo-June 14, 1864 ku-Edward no-Therese Alzheimer. Umndeni wabo wawuhlala eningizimu yeJalimane. Ngemva kokuphothula iziqu ngesidakamizwa sakhe sezokwelapha, i-Alzheimer yathatha isikhundla esibhedlela se-Community for Patient Mental and Epileptic ngo-1888.
Ngo-1902, yena nosebenza naye, u-Emil Kraepelin, bathatha isikhundla kwiRoyal Psychiatric Clinic yaseYunivesithi yaseMunich.
Izifo Zama-Alzheimer zaziwa kanjani?
Omunye weziguli zika-Alzheimer wayenguwesifazane ogama lakhe lingu-Auguste D, owayebekwe esibhedlela kusukela ngo-1901. Wayeneminyaka engu-51 ubudala futhi wabonisa izimpawu zokudangala kwengqondo , kuhlanganise nokulahleka kwememori , ukuphazamiseka , ukuphazamiseka , ukudideka, ukucabangela nokuhlukumeza . U-Alzheimer wamphatha futhi wabhala izimpawu zakhe ngokujula, kanye nezingxoxo zakhe naye. Uphawula ukuthi ngesikhathi esisodwa lapho u-Auguste engakwazi ukubhala kahle into ethile, wathi, "Ngizilahlekile."
Emva kuka-Auguste washona ngo-1906 eneminyaka engama-55 ubudala, i-Alzheimer yacela ukuba ubuchopho bakhe buhanjiswe kuye ukuze ahlolisise. Lapho efunda, wathola ukuthi iqukethe izici esizicabanga manje njengeziphawu zezifo ze-Alzheimer's, ikakhulukazi umakhi we-amyloid plaque kanye nama- neurofibrillary tangles .
Ubuchopho bakhe babuye babonisa i- cerebral atrophy, okunye okutholayo okufana nesifo se-Alzheimer's.
Kuyathakazelisa ukuthi kwakungakaze kube ngo-1995 ukuthi sithole amarekhodi wezokwelapha e-Alzheimer ekuboniseni ukunakekelwa kuka-Auguste D. nezingxoxo naye, kanye nesampula yamathisini akhe obuchopho. Amanothi akhe asinikeze ukuqonda okungaphezulu kokucwaninga kwe-Alzheimer futhi wavumela ososayensi ukuba baqinisekise ngokuqondile ubuchopho bashintsha ukuthi wayechazile enkulumweni yakhe.
I-Alzheimer yafa ngo-December 19, 1915. Wayeneminyaka engu-51 kuphela ubudala futhi wafa ngenxa yokutheleleka enhliziyweni yakhe.
Izifo Zama-Alzheimer Zithola Kanjani Igama Lalo?
Ngo-1906, i-Alois Alzheimer yanikeza inkulumo echaza izimpawu zika-Auguste kanye nezinguquko azibona ebuchosheni bakhe emva kokufa kwakhe. Ngo-1907, le nkulumo ishicilelwe. Kodwa-ke, akuzange kuthiwe nge-Alzheimer kuze kufike ngo-1910 lapho u-Emil Kraepelin, osebenza naye i-Alzheimer, ebhala ngendaba ka-Auguste D encwadini yesifo sengqondo futhi waqala ukuchaza ngokuthi "isifo se-Alzheimer."
Qaphela Inothi Nge-Alois Alzheimer
Ngokuthakazelisayo, ngo-1884 lapho i-Alzheimer eneminyaka engu-20 ubudala, wayebandakanyeka enkambeni yesango futhi uhlangothi lwakhe lwesobunxele lwahlukunyezwa inkemba. Kusukela ngaleso sikhathi, wayeqaphele ukuba abe nehlangothini elifanele lobuso bakhe oboniswe ezithombeni.
Olunye Umnikelo We-Alzheimer kuya Sayensi Nezokwelapha
I-Alzheimer yayiyingqayizivele kule nkathi ngezizathu eziningana.
Okokuqala, wayengusosayensi omuhle kakhulu, ethatha amanothi eningiliziwe futhi esebenzisa amasu okucwaninga yakamuva. Ngaphezu kokuthola isifo se-Alzheimer, ucwaningo lwakhe lwaluhlanganisa nokuthola okuqondile ukuguqulwa kobuchopho esifundeni sikaHuntington , i- arteriosclerosis kanye nesithuthwane .
I-Alzheimer nayo ibaluleke kakhulu ekukhulumeni nasekuxoxiseni ngeziguli zakhe ngesikhathi odokotela abaningi behlanganyela kancane kakhulu nalabo abakhathalelayo.
I-Alzheimer nayo ihlonishwa ngokusebenzisa izinqubomgomo ekukhoselweni kokuvimbela iziguli . Wayefuna ukuthi abasebenzi bakhe baphathe iziguli ngendlela engumuntu, bahlanganyele futhi baxoxe njalo nabo, futhi banikezele ngamanzi okugeza. Esikhathini esidlule, iziguli ezisekhoselweni zathola ukunakekelwa okuncane, futhi igumbi lokuzihlukanisa lalisetshenziswa njalo. Ngale ndlela, i-Alzheimer yenza isandla esikhulu ezweni lezokwelapha ngokuthinta ukuthi odokotela babheka kanjani futhi baphatha iziguli njengabantu ngabanye.
Imithombo:
I-Alzheimer's Association. Izinyathelo Ezinkulu Ezicwaningweni Ze-Alzheimer's and Brain Research. Ifinyelele ngoJanuwari 31, 2016. http://www.alz.org/research/science/major_milestones_in_alzheimers.asp
Izifo Zama-Alzheimer International. I-Alois Alzheimer. Ifinyelele ngoJanuwari 31, 2016. http://www.alz.co.uk/alois-alzheimer
Izingxoxo ku-Neuroscience Clinic. 2003 Mar; 5 (1): 101-108. Ukutholakala kwesifo se-Alzheimer. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181715/
Journal of Medical Biography. 2011 Feb; 19 (1): 32-3. I-Alois Alzheimer (1864-1915) kanye ne-Alzheimer syndrome. http://www.ncbi.nlm.nih.gov/pubmed/21350079
I-Lancet. UMnyango WezeMpilo. Auguste D nesifo so-Alzheimer. Vol 349 • Meyi 24, 1997. http://alzheimer.neurology.ucla.edu/pubs/alzheimerLancet.pdf
I-University of Rochester Medical Centre. Umlando. Ifinyelele ngoJanuwari 31, 2016. https://www.urmc.rochester.edu/alzheimers-care/history.aspx