Cishe amaphesenti angu-16 alabo abane-Down syndrome nabo bane-celiac.
Abantu abanesifo se-Down syndrome, isifo esijwayelekile sezakhi zofuzo, bathambekele ekuhlakuleleni isifo se-celiac emazingeni angaphezulu kwalabo bantu abaningi. Empeleni, isifo se-celiac singathinta abantu abangu-16 kubo bonke abantu abayi-100 abane-Down syndrome.
Kungani lokhu kwenzeka? Ngeshwa, odokotela abaqiniseki. Kodwa ukuxhumana okuqinile phakathi kwalezi zimo ezimbili kuyinto abazali nabazinakekeli babantu abane-Down syndrome okudingeka bayiqonde, ukuze bakwazi ukubuka izimpawu zesifo se-celiac bese behlola ukufaneleka okufanele kwenziwe , uma kunesidingo.
I-Down Syndrome Ingozi Nezinkinga Zezempilo
I-Down syndrome ibangelwa inkinga ngezakhi zakho zofuzo. Wonke umuntu unezinhlangothi ezingu-23 zezinhlobo zomzimba (uthola isigamu sezinyanga ezimbili kusuka kumama wakho nengxenye eyodwa koyihlo), kodwa abantu abanesifo se-Down syndrome banezinto ezakhiwe ngokwezakhi zofuzo kwelinye elilodwa lezakhi zofuzo: umbhangqwana wesibili. Lokhu kuholela ekutheni izakhi zofuzo zibiza ngokuthi "i-trisomy 21," igama lobuchwepheshe le-Down syndrome.
Lezo zinto ezengeziwe zofuzo zingavela ku-iqanda lomama wakho noma ubaba kababa, futhi ingozi ye-Down syndrome ikhuphuka ngenkathi unina (mhlawumbe ubaba, nakuba kungabikho bonke abacwaningi abathatha lo mbono). Cishe eyodwa kuzo zonke izingane ezingu-700 ezazalwa e-United States unyaka ngamunye-cishe izinkulungwane ezingu-6 000 ezinganeni-ine-Down syndrome.
Abantu abane-Down syndrome banezici zobuso ezihlukile , kufaka phakathi amehlo a-almond, ama-small ears kanye nomlomo, nekhanda elincane elivame ukuba libhebhe ngemuva.
Futhi bangaba nezwi elincane le-muscle, futhi bavame ukubhekana nezinkinga zezempilo ezivela embonweni nasekulahlekelweni kwezindlebe kuya ezintweni zenhliziyo. Bonke abantwana kanye nabantu abadala abane-Down syndrome banezinhlobo ezithile zokukhubazeka kwengqondo, nakuba izinga lalezi zingashintsha kakhulu kusuka komunye nomuntu.
Izinkinga nezinhlelo zokugaya ukudla nazo zivamile kulabo abane-Down syndrome.
Izingane ezizalwa nge-Down syndrome kungenzeka zingenalo i-anus egcwele ngokugcwele (okungalungiswa ngokuhlinzwa ngemuva kokuzalwa). Amaphesenti angu-5 ukuya ku-15 amaphesenti alabo abanesifo se-Down syndrome nabo bangase babe nesimo esibizwa ngokuthi yi-Hirschsprung, okwenzeka lapho intombazane enkulu ingasebenzi kahle. Lokhu kungase kudinge ukuhlinzwa ukuze kususwe ingxenye yezinambuzane ezinkulu ezingasebenzi.
Isifo Celiac: Esinye isimo se-Genetic
Njengesifo se-Down syndrome, isifo se-celiac yisimo sezakhi zofuzo -kukhulunywa, kudingeka ube okungenani oyedwa "isifo sofuba se-celiac" ukuthuthukisa isimo. Kodwa-ke, kunezinye izici ezihilelekile, ezinye zazo abazingakaboni. Akuwona wonke umuntu onjalo okuthiwa "izifo zesifo se-celiac" eziphethwe yisifo se-celiac.
Isifo se-Celiac futhi siyisimo sokuzimela , okusho ukuthi kuhilela ukuhlaselwa kwesinye somzimba wakho ngokuzivikela komzimba wakho. Uma une-celiac, ukudla ukudla okwenziwe ngenye yezinhlamvu ezintathu ze-gluten-noma i-hare, noma i-rye-kubangela ukuthi isimiso sakho somzimba sokuzivikela sikwazi ukuhlasela nokulimaza amathumbu akho amancane. Lokhu kunciphisa ikhono lakho lokuthola izakhi ezibalulekile ekudleni. Esimweni sayo esinzima kunazo zonke, isifo se-celiac singabangela ukungondleki okungathí sina, i-anemia, kanye nengozi ephakeme ye-lymphoma.
Abantu abane-Down syndrome banengozi enkulu kakhulu yezifo ezizimele ngokujwayelekile, futhi abacwaningi bakholelwa ukuthi amaphesenti angama-16 abantu abane-Down syndrome nabo banesifo se-celiac. Lokhu kuphakeme kakhulu kunezinga elilinganiselwa ku-1% emphakathini jikelele. Ochwepheshe banxusa abazali ukuba babe nezingane ezine-Down syndrome ezihlolwe isifo se- celiac ngokuhlolwa kwegazi okungenamkhawulo phakathi kweminyaka emibili nantathu.
Labo bantwana abanesibuko esihle bazodinga ukuba benze inqubo eyaziwa ngokuthi i-endoscopy ukuze odokotela bakwazi ukubheka ngqo bese beqoqa amasampula emigqa yabo yamathumbu. Lokhu kungase kuzwakale njengento enkulu, kodwa kuyisihluthulelo sokuthola isifo se-celiac esiqinisekisiwe .
Futhi, abazali abaningi abanezingane zabo ezitholile umbiko wokugcina wokugcina ukuthi ingane yabo yahamba ngomkhumbi ngaphandle kwezinkinga, nokuthi yayikudabukisa abazali ikakhulukazi kunabantwana.
Ukuthola Izifo Zama-Celiac Ngaphandle Kwezingane
Ngisho noma ingane yakho ye-Down syndrome iveza okungalungile isifo se-celiac njengengane encane, akufanele uvumele ukuqapha kwakho. Ngisho nabantu asebekhulile baye basanda kutholakala ukuthi bane-celiac , futhi kungenzeka ukuthuthukisa isimo nganoma yisiphi isikhathi. Akuyona nje inkinga yobuntwana.
Izimpawu eziyaziwa kakhulu zesifo se-celiac zibandakanya amanzi ehudo, ukukhathala, ukulahlekelwa isisindo, kanye ne- anemia . Kodwa-ke, abantu abaningi abanalo izimpawu "zakudala", futhi esikhundleni salokho banezimpawu ezingabandakanya ukuqotshwa , ubuhlungu obuhlangene , ngisho nokulahlekelwa izinwele . Izingane ezinesifo se-celiac zingase zikhule kancane kancane kunontanga futhi zingase zibe mfushane njengabantu abadala.
Izinkinga ezinjengokukhathazeka -ukungaphumeleli kokugula nokucindezeleka kungase kuvame kakhulu kubantu abanesifo se-celiac, futhi konke lokhu kungenzeka kubantu abane-Down syndrome, futhi.
Ucwaningo olulodwa oluholwa odokotela baseBoston Children's Hospital, lathola ukuthi imitholampilo ekhethekile ye-Down syndrome ayiphenyi njalo izimpawu zesifo se-celiac, ikakhulu lapho lezo zimpawu zingekho "izimpawu zakudala" ezivame ukuhambisana nesimo. Lelo cwaningo lwakhulume ukuqothulwa nezinkinga zokuziphatha njengezimpawu ezivame ukubikwa ngabanakekeli bezingane ababe behlolwe isifo se-celiac.
Kungenzeka ukuthi ube nesifo se-celiac ngaphandle kwanoma yiziphi izimpawu ezibonakalayo , kodwa amaqembu amabili abacwaningi abathola ukuthi abantu abane-Down syndrome abahlakulela isifo se-celiac cishe kunokuba bangabi nezimpawu ezibonakalayo, ikakhulukazi ukukhula kancane. Eqinisweni, isifundo esisodwa sathola ukuthi izingane ze-Down syndrome ezazisanda kutholakala ukuthi zinesifo se-celiac cishe zingaphansi kwe-10 percentile yokuphakama nesisindo.
Kodwa-ke, olunye ucwaningo lubonisa ukuthi izimpawu ezivamile ze-celiac-i-anemia, isifo sohudo, nokuqothulwa-zikhona njalo kwizingane ze-Down syndrome ngaphandle kwe-celiac. Kungenzeka futhi nalabo abanesifo se-celiac ukuthi benze umsebenzi ophansi we -roid, ongase ube khona lapho kungekho isifo se-celiac kulabo abane-Down syndrome. Ngakho-ke, abacwaningi bathi, abanakekeli nabahlengikazi kudingeka baqaphe futhi bahlole lesi simo.
Kunezinye izindaba ezinhle: isifundo esikhulu esivela eSweden sabonisa ukuthi abantu abanesifo se-Down syndrome nesifo se-celiac abanalo ingozi ephezulu yokufa kunabantu abane-Down syndrome yedwa.
Ukunakekela Umuntu Onesifo Esibucayi
Ngeshwa, okwamanje akakho imithi yokwelashwa yokuphatha imithi ye-celiac. Lokhu kungashintsha esikhathini esizayo, kepha kusukela manje, ukwelashwa okuphela kwesifo se-celiac yikudla okungekho gluten , okuyinto umuntu onama-celiac okumelwe alandele ukuphila.
I-gluten-free diet elula kakhulu ephepheni, kodwa kungaba nzima ekuziphatheni ngoba ukudla okuningi kunezinhlamvu ze gluten. Uma upheka umuntu onesifo se-celiac, udinga ukufunda amalebula ngokucophelela futhi uqaphele ukungcoliswa kwe-gluten ekhishini.
Eqinisweni, imindeni ethile yenza umkhuba wokudla i-gluten-ekhaya ekhaya ukuvikela impilo yelungu ngesifo se-celiac. Ukudla futhi kungaba yinselele, nakuba kutholakala lula ngokusabalalisa kwamamenyu e-gluten mahhala kokudla okusheshayo okuhlukahlukene nokudla okusheshayo kwezinsiza.
Izwi elivela
Uma ingane yakho inesifo se-Down syndrome, ucabangela ushintsho olukhulu njengokudla okungenayo i-gluten kungase kubonakale kunzima kakhulu, ikakhulu uma ingane yakho inezinye izinkinga zempilo ezivamile kulabo abane-Down syndrome. Ukukhulisa umntwana we-Down syndrome noma ukunakekela umuntu omdala kungaba yinselele, futhi ukwengeza imikhawulo ekhethekile yokudla ngeke kusize.
Kodwa kunezindaba ezinhle: asikho isidingo sokunciphisa ingane yakho yamakhukhi, i-pizza, nezinye izintandokazi zezingane, ngoba izinguqulo ezinhle ze-gluten zalezi zonke zokudla ziyatholakala kakhulu. Futhi, uma uke wazi kahle ijika lokufunda elivumile (elivumile ukuthi lihamba) eliza nokudla, cishe uzothola ukuthi lizoba uhlobo lwesibili, futhi ungase ubone ukuthi ezinye zezimpawu zokugaya ingane yakho nezinye izimpawu zithuthuka, futhi.
> Imithombo:
> Ludvigsson JF et al. Izifo ze-Celiac ne-Down Syndrome Ukufa: Isifundo Seqembu Likazwelonke. BMC Pediatrics. 2017 Jan 31; 17 (1): 41.
> National Down Syndrome Society. Ishidi leshidi lamathambo kanye ne-Down Syndrome.
> Mårild K et al. I-Down Syndrome ihlotshaniswa nenengozi ephakeme yezifo ze-Celiac: Isifundo Socwaningo Lwasezwelonke Wonke. I-Journal of Pediatrics. 2013 Jul; 163 (1): 237-42.
> Pavlovic M et al. Ukuhlolwa kwesifo se-Celiac ku-Down Syndrome - Amadalala amadala namasha. World Journal of Clinical Cases. 2017 Jul 16; 5 (7): 264-269.
> Sharr C et al. Ukuthola Izifo Zama-Celiac Ezigulane ezine-Down Syndrome. I-American Journal of Medical Genetics, Ingxenye A. 2016 Dec; 170 (12): 3098-3105.