Izinto Okufanele Uzigweme Uma Unesifo se-G6PD

I-Glucose 6 Ukuntuleka kwe-Phosphate Dehydrogenase (G6PD) yinhlobo ezuzwe njenge- anemia ye-hemolytic, uhlobo lwe-anemia eyenzeka lapho amangqamuzana abomvu egazi ephulwa phansi ngokushesha kunokujwayelekile (lokhu kubizwa ngokuthi i- hemolysis ). Ukuntuleka kwe-G6PD lokhu kwenzeka ngoba wenza inani elincishisiwe le-G6PD, i-enzyme evikela iseli elibomvu legazi kusuka emonakalweni. Ngenhlanhla, iningi labantu abanesifo se-G6PD abanalo izinkinga nsuku zonke. Kodwa-ke, kukhona imithi ethile noma ukudla okwandisa izinga lokuchiyeka kwegazi elibomvu. Ake sibukeze ezinye zezinto ezivamile ezingabangela izinkinga kule disorder yegazi.

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Ama-antibiotics

Abantu abanesifo se-G6PD bangakwazi ukubekezelela ama-antibiotic amaningi kodwa kufanele baqaphele abambalwa abakhethiweyo abangakwazi ukuqala ukuphazamiseka kwegazi elibomvu eliholela ekudleni kwegazi. Ama-antibiotics abizwa ngokuthi "izidakamizwa" kufanele agwenywe. Lezi zinambuzane zijwayele ukusetshenziselwa ukuphatha izifo zesikhumba noma izibilini. Ifomu elivame kakhulu lala ma-antibiotics lihamba ngamagama okuthiwa i-Septra noma i-Bactrim (sulfamethoxazole-trimethoprim).

Amagciwane okuthiwa "quinolone" kufanele futhi agwenywe. Ama-antibiotic amabili avame kakhulu kuleli qembu yi-Cipro (ciprofloxacin) ne-Levaquin (levofloxacin). Lawa ma-antibiotics avame ukusetshenziswa kubantu abadala ukuze baphathe izifo zokugoma kwamagciwane kanye ne-pneumonia. Amanye ama-antibiotic okufanele agwenywe afaka i-nitrofurantoin ne-dapsone.

Ngenhlanhla, kunezinhlobo eziningi zama-antibiotic ukuthi abantu abanokukhubazeka kwe-G6PD bangathatha ngokuphepha. Qinisekisa ukuxoxa ngalokhu nodokotela wakho uma unesifo se-G6PD futhi udinga ukwelashwa kwama-antibiotic.

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Imithi ye-Malaria

I-Primaquine, imithi esetshenziselwa ukuphatha noma yokuvimbela i- malaria , ingabangela izinkinga ze-hemolytic kubantu abane-G6PD ukuntuleka. Ngenxa yalokhu kunzima, kunconywa ukuthi abantu bahlolwe ukulahlekelwa kwe-G6PD ngaphambi kokuthatha i-primaquine. Lokhu kubandakanya ukuncelisa izingane ezinomama omama abazithatha i-primaquine. Ngenhlanhla, ezinye izidakamizwa ezisetshenziselwa ukwelapha i-malaria zibekezelela abantu abaningi abanokuntuleka kwe-G6PD.

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Imithi Esetshenziswa Ekwelashweni Kwemdlavuza

I-Rasburicase imithi esetshenziselwa ukwelapha i-tumor lysis syndrome, ukuxilongwa kwezokwelapha ze-hematologic kansa efana ne-leukemia, akufanele isetshenziswe kubantu abanokuntuleka kwe-G6PD. Ngenxa yengozi, kunconywa ukuthi abantu bahlolwe ngaphambi kokuthola i-rasburicase. Ngokufanayo, i-doxorubicin, uhlobo lwe-chemotherapy olusetshenziselwa ukwelapha izinhlobo eziningi zomdlavuza, lingabangela ukuchithwa kwegazi elibomvu kubantu abanezinhlobo ezithile zokuntuleka kwe-G6PD.

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Aspirin

I-aspirin, ejwayele ukusetshenziselwa ukuphatha ubuhlungu noma ukuvuvukala, kufanele igwenywe. Abanye abantu bathatha i-aspirin nsuku zonke njengengxenye yokwelashwa kwabo. Uma ugwema i-aspirin, kubalulekile ukukhumbula ukuthi itholakala kumaningi ngaphezu kwemithi ephikisana nayo njenge-Anacin, Bufferin, Ecotrin, Excedrin, BC Powders kanye ne-Goody's Powders. Itholakala ku-Pepto-Bismol. Ngokuvamile ezinye phezu kokunciphisa ubuhlungu be-counter counter like acetaminophen noma ibuprofen zibekezelela ngaphandle kwezinkinga.

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Ama-Mothballs

Yebo, abantu basebenzisa ama-mothballs. I-mothballs ingaqukatha ikhemikhali eyaziwa ngokuthi i-naphthalene engabangela i-hemolysis kubantu abanokuntuleka kwe-G6PD. Ama-naphthalene nawo angatholakala ema-fumigants, ikakhulukazi lawo asetshenziselwa ukugcina izinyoka. I-Naphthalene iyisiphunga esinikezwa yizimikhiqizo ukuze ukutholakala kwemvelo kungase kutholakale ngokuvula umoya noma ukuwafaka.

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I-Henna

Kukhona imibiko yenkampani eshicilelwe eveza i-henna (esetshenziselwa ama-tattoos okwesikhashana noma udayisi wezinwele) ibangele izinkinga ze-hemolytic kubantu abanokuntuleka kwe-G6PD. Izinsana ezineminyaka engaphansi kwezinyanga ezimbili zibonakala zingase zikwazi ukubhekana nale mpendulo.

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Ubhontshisi be-Fava

Ukuntuleka kwe-G6PD kuthiwa yi-favism; ikakhulukazi izinhlobo ezinzima kakhulu zokuntuleka kwe-G6PD. Lokhu kungenxa yokuthi ukungenisa ubhontshisi be-fava (owaziwa njengebhontshisi obanzi) kungabangela ukuhlaselwa kwe-hemolytic kwiziguli ezine-G6PD. Abanye basikisela ukuthi zonke izitshalo (njenge-peas, lentils, noma amantongomane) zigwenywe, kodwa noma ngabe lokhu kuyadingeka yini noma cha akuyazi.

Izwi elivela

Uma unesifo se-G6PD, akusho ukuthi awukwazi ukuthatha imithi. Kufanele uqaphele imithi ejwayelekile yokugwema. Lokhu akulona uhlu oluphelele lwezinto abantu abanokukhubazeka kwe-G6PD okufanele bakugweme. Kunezinye izidakamizwa ezibangelwa ukuhlakazeka kwamaseli abomvu uma kuthathwa amanani aphezulu. Ezinye ziqala kuphela izinkinga ezinhlobonhlobo ezithile zokuntuleka kwe-G6PD. Qinisekisa ukuthi uxoxisana nayo yonke imithi yakho entsha nodokotela wakho ukuqinisekisa ukuthi awuphikisiwe kubantu abanesifo se-G6PD.

> Umthombo:
> Luzaatto L no Poggi V. I-Glucose-6-Phosphate Dehydrogenase Ukuntuleka. Ku: Orkin SH, Fisher DE, Ginsburg D, Bheka AT, Lux SE kanye Nathan DG (Eds). I-Hematology ne-Oncology ye-Infancy ne-Childhood (8th ed). I-Philadelphia: Elsevier.