Ingabe ulambile, ukhathele noma ucindezelekile? Ingabe bewazi ukuthi kukhona i-hormone noma ukungalingani kwe-hormone ngemuva kwalowo mzwa?
Amakhomoni amakhemikhali akhiqizwa umzimba wakho. Benza njengezithunywa ezisiza ukulawula nokuqondisa ukuthi umzimba wakho usebenza kanjani futhi uphendula imvelo yakho. Unezinhlayiya ezikhethekile emzimbeni wakho okhiqiza futhi ukhululeke ama-hormone uma usho uphawu lobuchopho bakho.
Futhi une-receptors ekhethekile ye-hormone emzimbeni wakho owamukela le miyalezo yamakhemikhali. I-hormone ehilelekile ekukhiqizeni kanye nokuthuthukiswa kwezitho zakho zobulili kuthiwa amahomoni ocansi.
Kwabesifazane, i-hormone enkulu ye-sex is estrogen.
Akuyona nje i-Estrogen eyodwa kuphela
Umzimba wakho uveza izinhlobo ezintathu ze-estrogen . Ngesikhathi sokuphila kwakho, inani lalezi zi-estrogens ezahlukene zizoshintsha.
- I-Estradiol (E2) : I-Estradiol yi-estrogen enkulu emzimbeni wakho phakathi neminyaka yakho yokubeletha. Lesi yisikhathi esivela nje ngaphambi kwesikhathi sakho sokuqala kuze kube sesikhathini sakho sokugcina noma esikhathini sokuphela kwesikhathi. Phakathi nalesi sikhathi, inani elilinganiselwe le-estradiol egazini lakho legazi lingaphezulu kunezinye izinhlobo ze-estrogen. I-Estradiol nayo inomthelela oqine kakhulu kwi-estrogen ye-hormone receptors yomzimba wakho. I-Estradiol ikhiqizwa emaqanda akho. Inani le-estradiol elikhiqizwa ama-ovari wakho lihluka ngaphezu komjikelezo wakho wenyanga ukuya esikhathini . Nakuba iningi le-estradiol yakho ikhiqizwa i-ovary yakho, inani elincane likhiqizwa kolunye uhlobo lwe-estrogen, estrone.
- I-Estrone (E1): I-Estrone iyinhlobo yesibili ejwayelekile ye-estrogen eyenziwa ngumzimba wakho ngesikhathi sokubeletha. Ibuye ibe nomthelela obuthakathaka kune-estradiol emzimbeni womzimba we-estrogen ekhethekile ye-hormone receptors. I-Estrone ngokuyinhloko isenziwa kolunye uhlobo lwe-hormone yezocansi emzimbeni wakho obizwa ngokuthi i-androgens. Inqubo ekhethekile ye-biochemical ebizwa ngokuthi i-aromatization ishintsha i-androgen ibe yi-estrone. Le nqubo iyenzeka ikakhulukazi emzimbeni wakho we-adipose noma ama-fat cells nasesiswini sakho. Isamba esincane kuphela se-estrone sikhiqizwa i-ovary yakho. Ngesikhathi sokuya esikhathini, uma ama-ovaries akho ayeka ukukhiqiza ama-hormone, i-estrone yilona uhlobo olulodwa lwe-estrogen olukhiqizwa umzimba wakho.
- I-Estriol (E3): I- Estriol ivame ukubizwa nge-estrogen yokukhulelwa. Ikhona kuphela esincane kakhulu-esingaqondakali-inani elingaphakathi kwegazi lakho uma ungakhulelwe. Kuzo zonke izinhlobo ze-estrogen, kunomthelela obuthakathaka emitholampilo ye-estrogen yomzimba wakho. Nakuba zonke izinhlobo zamazinga e-estrogen zanda uma ukhulelwe, amazinga e-estriol akhula kakhulu. I-placenta inesibopho sokukhuphuka okuphawulekayo ekukhiqizweni kwe-estriol ngesikhathi sokukhulelwa. I-Estrogen idlala indima ebalulekile ekukhulelweni, ekukhuthazeni ukukhula komntwana kanye nentuthuko ekulungiseleleni amabele akhokhelo.
Umsebenzi We-Estrogen Emzimbeni Wakho
Inendima yayo njenge-hormone enkulu emzimbeni wakho, i-estrogen yenza izinto ezibaluleke kakhulu ngisho noma ungakhulelwe. Njenge-hormone, i-estrogen (ikakhulukazi i-estradiol) yenza izingxenye zomzimba wakho ezine-estrogen ezithile ze-hormone receptors. Nazi ezinye izinto ezibalulekile i-estrogen ehilelekile emzimbeni wakho:
Ukuthuthukiswa ngokocansi: I- Estrogen inesibopho sokukhula nokuqhubeka nokuthuthukiswa kwe-anatomy yakho yokuzala kuhlanganise nesiswini sakho nesisu. Kubuye kube nesibopho ekuthuthukiseni amabele akho nokukhula kwezinwele zakho ze-pubic kanye ne-armpit ngesikhathi sokukhulelwa.
Ngokubili lezi zinguquko zikhomba ukufika okuzayo kwesikhathi sakho sokuya esikhathini esiqala ukuqala kweminyaka yakho yokubeletha.
Umjikelezo wakho wokuya esikhathini: Inhloso esemqoka yokujikeleza kokuya esikhathini ukulungiselela umzimba wakho ukukhulelwa. Uma ungakhulelwa ngesikhathi somjikelezo wanyangazonke, isibeletho sakho sibeka umgqa wayo futhi uthola isikhathi sakho. I-Estrogen yi-hormone ephathekayo yokwakha ububanzi besikhumba sakho njalo ngenyanga ukulungiselela ukukhulelwa.
Ukuthuthukiswa kwamathambo nempilo: I- Estrogen inendima ebalulekile ekuthuthukiseni kahle amathambo akho. Ibuye ilandise ukubuyiswa kwamathambo emathanjeni akho omdala futhi ivikela ukulahleka kwethambo.
Ngesikhathi sokuya esikhathini, uma amazinga e-estrogen ewa, kukhona ukwanda okuphawulekayo ekulahlekelweni kwethambo ngoba umphumela wokuzivikela wesonto womzimba wakho ulahlekile. Lokhu kwanda okukhulu ekulahlekelweni kwethambo kungabangela ukuba i- osteoporosis , okukubeka engozini enkulu yokuqhekeka kwe-hip.
Impilo yenhliziyo: I- Estrogen isiza ukuvikela isifo senhliziyo. I-Estrogen yenza izinto eziningi ezinhle emzimbeni wakho ukusiza ukugcina imithwalo yegazi yakho iphilile, kuhlanganise nokunciphisa ukuvuvukala nokulawula amazinga akho e-cholesterol. Ukubambisana ndawonye, umphumela omuhle we-estrogen ekuvinjweni kwesifo senhliziyo kubalulekile kubesifazane besandulela. Ngesikhathi sokumisa esikhathini, lapho umphumela wokuzivikela we-estrogen ususile, kunokwanda okuqhubekayo kwesifo senhliziyo kwabesifazane . Kakhulu kangangokuthi imbangela ehamba phambili yokufa kwabesifazane base-US ivela ezinkingeni zesifo senhliziyo.
Ukuphathwa kwemizwa : I- Estrogen inomphumela omuhle ebuchosheni bakho. Kucatshangwa ukuthi imiphumela ye-estrogen indlela izakhiwo zakho zobuchopho ezixhunyiwe ngayo, ukuthi amangqamuzana akho obuchopho akhuluma kanjani, ngisho nokuma kobuchopho bakho. I-Estrogen nayo inendima enkulu emoyeni wakho. Unomthelela omkhulu kunomunye wamakhemikhali akho ebuchopho okuthiwa i-serotonin. I-Serotonin yikhemikhali yokulinganisela kwemizwa ebuchosheni bakho. Kuvela ukuthi i-estrogen ikhuthaza ukwenziwa kwe-serotonin ebuchosheni bakho. Lokhu kusho ukuthi izinga lakho le-estrogen liphansi kakhulu izinga lakho le-serotonin lizokwehla futhi. Umphumela walokhu kubaluleke kakhulu kwabanye besifazane. Kucatshangwa ukuthi lehla ehlobene ne-estrogen ehlobene nokukhiqizwa kwe-serotonin inomthelela ekucindezelekeni kokuthunyelwa komzimba nokuxoshwa kwamadoda.
Izwi elivela
I-Estrogen iyi-hormone ebaluleke kakhulu kwabesifazane. Akukona nje ukuma isibalo sakho futhi kuthinte umjikelezo wakho wokuya esikhathini, futhi kukunika amandla okuba nezingane futhi ngisho nokuncelisa izingane. Ngaphandle kwalezi zinto eziyingqayizivele zezinsikazi, yenza okuningi ngemuva kwezigcawu ukusebenza ukuze kugcine umzimba wakho uphelele futhi unempilo.
Ngezinye izikhathi empilweni yakho lapho amazinga e-estrogen wakho engalingani, cishe ngeke uzizwe uthanda wena. Phakathi neminyaka yakho yokuzala, izinguquko esikhathini sakho ziyisikhombisa esihle sokungalingani kwe-estrogen okungenzeka. Ukunqamuka kwesikhashana kanye nokuguqulwa kwe-menopausal kunezikhathi zokuchasisa kwe-estrogen ukungalingani. Qinisekisa ukuxoxa nganoma yiziphi izinguquko emjikelezweni wakho wokuya esikhathini nomhlinzeki wakho wezempilo. Ukuqonda ama-hormone akho kuzokusiza uphile kahle kuzo zonke izigaba zokuphila kwakho.
> Imithombo:
> Barth, C., Villringer, A., & Sacher, J. (2015). Ama-hormone e-sex asithinta ama-neurotransmitter futhi ahlele ubuchopho besifazane omdala phakathi nezinkathi zokuguquguquka kwe-hormonal. Imingcele e-Neuroscience , 9 , 37. http://doi.org/10.3389/fnins.2015.00037
> Pérez-López, FR, Larrad-Mur, L., Kallen, A., Chedraui, P., & Taylor, HS (2010). Ukwahluka Kwesilisa Ngesifo Sezinhliziyo: Izithonya Ze-Hormonal and Biochemical. Isayensi Yokuzala (Izinkulungwane Zama-Oaks, Calif.) , 17 (6), 511-531. http://doi.org/10.1177/1933719110367829
> Shapiro, M. (2012). Ukunqamuka kwesikhashana > ukujwayela >: Umhlahlandlela womtholampilo, umagazini we-4. I-Canadian Family Physician , 58 (9), 989.